Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jonasz Jeremiasz Weber"'
Autor:
Jonasz Jeremiasz Weber, Maria do Carmo Costa, K. Matthew Scaglione, Sokol V. Todi, Huu Phuc Nguyen
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Externí odkaz:
https://doaj.org/article/b756a0369c9d478a9a21deaf064cac2d
Autor:
Priscila Pereira Sena, Jonasz Jeremiasz Weber, Sercan Bayezit, Rafael Saup, Rana Dilara Incebacak Eltemur, Xiaoling Li, Ana Velic, Jaqueline Jung, Boris Macek, Huu Phuc Nguyen, Olaf Riess, Thorsten Schmidt
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Lysine residues are one of the main sites for posttranslational modifications of proteins, and lysine ubiquitination of the Machado-Joseph disease protein ataxin-3 is implicated in its cellular function and polyglutamine expansion-dependent toxicity.
Externí odkaz:
https://doaj.org/article/ab398446675b41ffa6299a6e3522a89b
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Among posttranslational modifications, directed proteolytic processes have the strongest impact on protein integrity. They are executed by a variety of cellular machineries and lead to a wide range of molecular consequences. Compared to other forms o
Externí odkaz:
https://doaj.org/article/d73f02fd395b4896a1b7ffd8fc9ceb68
Autor:
Libo Yu-Taeger, Arianna Novati, Jonasz Jeremiasz Weber, Elisabeth Singer-Mikosch, Ann-Sophie Pabst, Fubo Cheng, Carsten Saft, Jennifer Koenig, Gisa Ellrichmann, Taneli Heikkinen, Mahmoud A. Pouladi, Olaf Riess, Huu Phuc Nguyen
Publikováno v:
Cells, Vol 11, Iss 23, p 3779 (2022)
Body weight (BW) loss and reduced body mass index (BMI) are the most common peripheral alterations in Huntington disease (HD) and have been found in HD mutation carriers and HD animal models before the manifestation of neurological symptoms. This sug
Externí odkaz:
https://doaj.org/article/182d9543377f43cc8144fbbfc702c74e
Autor:
Stefanie Nicole Hayer, Yvonne Schelling, Jeannette Huebener-Schmid, Jonasz Jeremiasz Weber, Stefan Hauser, Ludger Schöls
Publikováno v:
Stem Cell Research, Vol 30, Iss , Pp 171-174 (2018)
A skin biopsy of a patient with spinocerebellar ataxia type 3 (SCA3, also known as Machado-Joseph disease (MJD)) caused by a CAG trinucleotide repeat expansion in the ATXN3 gene, was used to generate an induced pluripotent stem cell line, HIHCNi002-A
Externí odkaz:
https://doaj.org/article/abf89968d65f486d89c08f12dea60aa6
Autor:
Huu Phuc Nguyen, Jeannette Hübener, Jonasz Jeremiasz Weber, Stephan Grueninger, Olaf Riess, Andreas Weiss
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62043 (2013)
Spinocerebellar Ataxia Type 3 (SCA3), also known as Machado-Joseph disease, is an autosomal dominantly inherited neurodegenerative disease caused by an expanded polyglutamine stretch in the ataxin-3 protein. A pathological hallmark of the disease is
Externí odkaz:
https://doaj.org/article/af7c6bade86045dbbdeae5a70561c91e
Autor:
Jonasz Jeremiasz Weber, Stefanie Cari Anger, Priscila Pereira Sena, Rana Dilara Incebacak Eltemur, Chrisovalantou Huridou, Florian Fath, Caspar Gross, Nicolas Casadei, Olaf Riess, Huu Phuc Nguyen
Publikováno v:
A: Pathogenic mechanisms.
Autor:
Libo Yu-Taeger, Arianna Novati, Jonasz Jeremiasz Weber, Elisabeth Singer-Mikosch, Ann-Sophie Pabst, Carsten Saft, Jennifer König, Gisa Ellrichmann, Taneli Heikkinen, Mahmoud A Pouladi, Olaf Riess, Huu Phuc Nguyen
Publikováno v:
A: Pathogenic mechanisms.
Autor:
Jonasz Jeremiasz Weber, Stefanie Cari Anger, Priscila Pereira Sena, Rana Dilara Incebacak Eltemur, Chrisovalantou Huridou, Florian Fath, Caspar Gross, Nicolas Casadei, Olaf Riess, Huu Phuc Nguyen
Publikováno v:
Cellular and Molecular Life Sciences. 79
Spinocerebellar ataxia type 17 (SCA17) is a neurodegenerative disease caused by a polyglutamine-encoding trinucleotide repeat expansion in the gene of transcription factor TATA box-binding protein (TBP). While its underlying pathomechanism is elusive
Autor:
Jonasz Jeremiasz Weber
Together with cancer and cardiovascular disorders, neurodegenerative diseases such as Alzheimer and Parkinson disease are an increasingly important medical issue for the aging society of the 21st century. Multiple factors such as environmental influe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581acd1ccdf5fd5df068b8c31047a7a3