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pro vyhledávání: '"Jonason Yang"'
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100156- (2020)
Summary: Patient-derived xenografts (PDXs) are the most valuable tool for preclinical drug testing because they retain the genetic diversity and phenotypic heterogeneity of the original tumor. Acute myeloid leukemia (AML) remains difficult to engraft
Externí odkaz:
https://doaj.org/article/336f987c4cac4686917f8e814354334b
Acute myeloid leukemia (AML) is a difficult-to-treat blood cancer. A major challenge in treating patients with AML is relapse, which is caused by the persistence of leukemia stem cells (LSCs). Self-renewal is a defining property of LSCs and its dereg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20306f00c77ec0e76ab127cb85d6e2a7
http://www.intechopen.com/articles/show/title/self-renewal-pathways-in-acute-myeloid-leukemia-stem-cells
http://www.intechopen.com/articles/show/title/self-renewal-pathways-in-acute-myeloid-leukemia-stem-cells
Autor:
Nunki Hassan, Franklin Chen, Jonason Yang, Jayvee Datuin, Lucie Gaspard-Boulinc, Jenny Y. Wang, Hangyu Yi
Publikováno v:
Blood. 136:31-31
Acute myeloid leukemia (AML) is a heterogenous malignancy, where the persistence of chemo-resistant leukemia stem cells (LSCs) contributes to disease relapse. We have previously demonstrated the clinical significance of WNT/β-catenin signaling in dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0c330747f9c3bb9922335ee73d37fe8
https://doi.org/10.1182/blood-2020-142389
https://doi.org/10.1182/blood-2020-142389