Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jonas Weidenhausen"'
Autor:
Xiaodi Gong, Jean-Baptiste Boyer, Simone Gierlich, Marlena Pożoga, Jonas Weidenhausen, Irmgard Sinning, Thierry Meinnel, Carmela Giglione, Yonghong Wang, Rüdiger Hell, Markus Wirtz
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113768- (2024)
Summary: The ribosome-tethered N-terminal acetyltransferase A (NatA) acetylates 52% of soluble proteins in Arabidopsis thaliana. This co-translational modification of the N terminus stabilizes diverse cytosolic plant proteins. The evolutionary conser
Externí odkaz:
https://doaj.org/article/ff204367416745e1aad4c13986b70397
Publikováno v:
PLoS ONE, Vol 19, Iss 9, p e0307850 (2024)
DNMT1 is an essential DNA methyltransferase that catalyzes the transfer of methyl groups to CpG islands in DNA and generates a prominent epigenetic mark. The catalytic activity of DNMT1 relies on its conformational plasticity and ability to change co
Externí odkaz:
https://doaj.org/article/b789a589554c4fb09c86f2d0df3d1315
Autor:
Leo Kiss, Tyler Rhinesmith, Jakub Luptak, Claire F. Dickson, Jonas Weidenhausen, Shannon Smyly, Ji-Chun Yang, Sarah L. Maslen, Irmgard Sinning, David Neuhaus, Dean Clift, Leo C. James
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract TRIM proteins are the largest family of E3 ligases in mammals. They include the intracellular antibody receptor TRIM21, which is responsible for mediating targeted protein degradation during Trim-Away. Despite their importance, the ubiquitin
Externí odkaz:
https://doaj.org/article/9847497c03534f53b81f80ff92484d91
Autor:
Jonas Weidenhausen, Jürgen Kopp, Carmen Ruger-Herreros, Frank Stein, Per Haberkant, Karine Lapouge, Irmgard Sinning
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10805 (2022)
Most eukaryotic proteins are N-terminally acetylated by a set of Nα acetyltransferases (NATs). This ancient and ubiquitous modification plays a fundamental role in protein homeostasis, while mutations are linked to human diseases and phenotypic defe
Externí odkaz:
https://doaj.org/article/12a2f9b3048246f18b3f5c4e19ac4273
Autor:
Leo Kiss, Tyler Rhinesmith, Claire F Dickson, Jonas Weidenhausen, Shannon Smyly, Jakub Luptak, Ji-Chun Yang, Sarah L Maslen, Irmgard Sinning, David Neuhaus, Dean Clift, Leo C James
TRIM proteins are the largest family of E3 ligases in mammals. They include the intracellular antibody receptor TRIM21, which is responsible for mediating targeted protein degradation during Trim-Away. Despite their importance, the ubiquitination mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ff087e88dc61ef593889cbe848b8038
https://doi.org/10.1101/2022.06.29.498105
https://doi.org/10.1101/2022.06.29.498105
Autor:
Pavlína, Miklánková, Eric, Linster, Jean-Baptiste, Boyer, Jonas, Weidenhausen, Johannes, Mueller, Laura, Armbruster, Karine, Lapouge, Carolina, De La Torre, Willy, Bienvenut, Carsten, Sticht, Matthias, Mann, Thierry, Meinnel, Irmgard, Sinning, Carmela, Giglione, Rüdiger, Hell, Markus, Wirtz
Publikováno v:
Science advances. 8(24)
In humans, the Huntingtin yeast partner K (HYPK) binds to the ribosome-associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::16228f889ba2c21d1dea4ac3987e1fe2
https://pubmed.ncbi.nlm.nih.gov/35704578
https://pubmed.ncbi.nlm.nih.gov/35704578
Autor:
Eric Linster, Willy V. Bienvenut, Markus Wirtz, Carmela Giglione, Thierry Meinnel, Jürgen Eirich, Jonas Weidenhausen, Iris Finkemeier, Ruediger Hell, Jean-Baptiste Boyer, Iwona Stephan, Irmgard Sinning, Laura Armbruster, Annika Brünje
Publikováno v:
Plant Physiology
Plant Physiology, 2020, 182 (2), pp.792-806. ⟨10.1104/pp.20.00222⟩
Plant Physiology, American Society of Plant Biologists, 2020, 182 (2), pp.792-806. ⟨10.1104/pp.20.00222⟩
Plant Physiology, American Society of Plant Biologists, 2020, 183 (4), pp.1502-1516. ⟨10.1104/pp.20.00222⟩
Plant Physiology, 2020, 183 (4), pp.1502-1516. ⟨10.1104/pp.20.00222⟩
Plant Physiology, 2020, 182 (2), pp.792-806. ⟨10.1104/pp.20.00222⟩
Plant Physiology, American Society of Plant Biologists, 2020, 182 (2), pp.792-806. ⟨10.1104/pp.20.00222⟩
Plant Physiology, American Society of Plant Biologists, 2020, 183 (4), pp.1502-1516. ⟨10.1104/pp.20.00222⟩
Plant Physiology, 2020, 183 (4), pp.1502-1516. ⟨10.1104/pp.20.00222⟩
International audience; N a-terminal acetylation (NTA) is a prevalent protein modification in eukaryotes. In plants, the biological function of NTA remains enigmatic. The dominant N-acetyltransferase (Nat) in Arabidopsis (Arabidopsis thaliana) is Nat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::663735bded8b6880418d43a13bcd856e
http://hdl.handle.net/20.500.12278/113192
http://hdl.handle.net/20.500.12278/113192
Autor:
Jonas Weidenhausen, Jürgen Kopp, Karine Lapouge, Markus Wirtz, Irmgard Sinning, Laura Armbruster
Publikováno v:
Structure. 29:413-425.e5
The majority of eukaryotic proteins is modified by N-terminal acetylation, which plays a fundamental role in protein homeostasis, localization, and complex formation. N-terminal acetyltransferases (NATs) mainly act co-translationally on newly synthes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c96023bfe2ff242e0fc253573b02ef0c
https://doi.org/10.1016/j.str.2020.12.004
https://doi.org/10.1016/j.str.2020.12.004