Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Jonas Vikeså"'
Autor:
Daniela Castanotto, Xiaowei Zhang, Jacqueline Rüger, Jessica Alluin, Ritin Sharma, Patrick Pirrotte, Lars Joenson, Silvia Ioannou, Michael S. Nelson, Jonas Vikeså, Bo Rode Hansen, Troels Koch, Mads Aaboe Jensen, John J. Rossi, Cy A. Stein
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 23, Iss , Pp 63-75 (2021)
The androgen receptor (AR) plays a critical role in the development of prostate cancer (PCa) through the activation of androgen-induced cellular proliferation genes. Thus, blocking AR-mediated transcriptional activation is expected to inhibit the gro
Externí odkaz:
https://doaj.org/article/05d438d8c2914f6a92b4a9a5650737aa
Autor:
Lars Jønson, Jan Christiansen, Thomas V.O. Hansen, Jonas Vikeså, Yohei Yamamoto, Finn C. Nielsen
Publikováno v:
Cell Reports, Vol 7, Iss 2, Pp 539-551 (2014)
Summary: The IMP3 RNA-binding protein is associated with metastasis and poor outcome in human cancer. Using solid cancer transcriptome data, we found that IMP3 correlates with HMGA2 mRNA expression. Cytoplasmic IMP3 granules contain HMGA2, and IMP3 d
Externí odkaz:
https://doaj.org/article/6e89700f7646480cb5c1d54eec67e9c6
Autor:
Signe Tang Karlsen, Troels Koch, Jonas Vikeså, Morten Lindow, Pia Særmark, Lykke Pedersen, Peter Hagedorn
Publikováno v:
Molecular Therapy. Nucleic Acids
Well-validated strategies for discovering potent and efficacious antisense oligonucleotides are central to realize the full therapeutic potential of RNA therapy. In this study, we focus on RNA targets where the same sequence of 16-20 nt is found in s
Autor:
Ritin Sharma, Jessica Alluin, Silvia Ioannou, Lars Joenson, Troels Koch, Patrick Pirrotte, Mads Jensen, Xiaowei Zhang, Jonas Vikeså, Bo Hansen, Daniela Castanotto, Michael S. Nelson, Cy A. Stein, John J. Rossi, Jacqueline Rüger
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 23, Iss, Pp 63-75 (2021)
Molecular Therapy: Nucleic Acids, Vol 23, Iss, Pp 63-75 (2021)
The androgen receptor (AR) plays a critical role in the development of prostate cancer (PCa) through the activation of androgen-induced cellular proliferation genes. Thus, blocking AR-mediated transcriptional activation is expected to inhibit the gro
Publikováno v:
Clinical Case Reports
Key Clinical Message Hematology analyzers sometimes generate spurious results. A patient had EDTA-induced pseudothrombocytosis and platelet agglutination in citrate blood samples. This case verifies that addition of 1% paraformaldehyde to the citrate
Publikováno v:
The Laryngoscope. 127:E201-E208
Objectives/Hypothesis The function of the human endolymphatic sac (ES) has been enigmatic for decades. Hypotheses include controlling endolymphatic fluid homeostasis and inner ear immunological defense. Additionally, several studies indicate a possib
Autor:
Hannah Pendergraff, Christian Weile, Jonas Vikeså, Charlotte Øverup, Troels Koch, Steffen Schmidt, Marie W. Lindholm
Publikováno v:
Nucleic Acid Therapeutics
Methods for the quantification of antisense oligonucleotides (AONs) provide insightful information on biodistribution and intracellular trafficking. However, the established methods have not provided information on the absolute number of molecules in
Autor:
Jonas Vikeså, Christina Kjær, Tina Binderup, Andreas Kjaer, Birgitte Federspiel, Lennart Friis-Hansen, Kristina B V Døssing, Michael D. Culler, Ulrich Knigge
Publikováno v:
Genes
Genes, Vol 9, Iss 7, p 337 (2018)
Volume 9
Issue 7
Døssing, K B V, Kjær, C, Vikeså, J, Binderup, T, Knigge, U, Culler, M D, Kjær, A, Federspiel, B & Friis-Hansen, L 2018, ' Somatostatin analogue treatment primarily induce miRNA expression changes and up-regulates growth inhibitory miR-7 and miR-148a in neuroendocrine cells ', Genes, vol. 9, no. 7, 337 . https://doi.org/10.3390/genes9070337
Genes, Vol 9, Iss 7, p 337 (2018)
Volume 9
Issue 7
Døssing, K B V, Kjær, C, Vikeså, J, Binderup, T, Knigge, U, Culler, M D, Kjær, A, Federspiel, B & Friis-Hansen, L 2018, ' Somatostatin analogue treatment primarily induce miRNA expression changes and up-regulates growth inhibitory miR-7 and miR-148a in neuroendocrine cells ', Genes, vol. 9, no. 7, 337 . https://doi.org/10.3390/genes9070337
Somatostatin (SST) analogues are used to control the proliferation and symptoms of neuroendocrine tumors (NETs). MicroRNAs (miRNA) are small non-coding RNAs that modulate posttranscriptional gene expression. We wanted to characterize the miRNAs opera
Publikováno v:
The Laryngoscope. 125:E269-E275
Objectives/Hypothesis The purpose of the present study is to explore, demonstrate, and describe the expression of genes related to the innate immune system in the human endolymphatic sac. It is hypothesized that the endolymphatic sac has a significan
Publikováno v:
Otologyneurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 38(5)
INTRODUCTION Recent studies suggest that the human endolymphatic sac (ES) may have multiple functions, including an ion-transport capacity comparable to the kidney, an immunological capacity and a possible natriuretic capacity. Further, there have be