Výsledky vyhledávání - "Jonas Stanke"

Analysis of 4 Single-Nucleotide Polymorphisms in Relation to Cervical Dysplasia and Cancer Development Using a High-Throughput Ligation-Detection Reaction Procedure

Autor: Ursula Schiller, Thomas Bergmann, Andreas M. Kaufmann, Corinna Hoffmann, Achim Schneider, Miriam Schuetz, Hans Lehrach, Helmut von Keyserling, Jonas Stanke, Andreas Dahl

Publikováno v: International Journal of Gynecologic Cancer. 21:1664-1671

BackgroundHost genetic characteristics and environmental factors may correlate with risk for cervical cancer development. Here we describe a retrospective screening study for single nucleotide polymorphisms (SNPs) in genetic markersTP53, MTHFR, CYP1A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b197e03b1b3f022c7332deff87e8f514
https://doi.org/10.1097/igc.0b013e31822b6299

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A flow cytometry-based assay to assess minute frequencies of CD8+ T cells by their cytolytic function

Autor: Jonas Stanke, Corinna Hoffmann, Andreas M. Kaufmann, Stefan Stevanovic, Ulrike Erben, Achim Schneider, Guenter Cichon, Helmut von Keyserling

Publikováno v: Journal of Immunological Methods. 360:56-65

Limited sample size and low sensitivity of currently used functional assays challenge direct analysis of cytotoxic CD8+ T lymphocyte activity to quantify antigen-specific immunity after infection or vaccination. Our flow cytometry-based assay reprodu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfd4ad2f97ebdcfabbbc744f8127a5a0
https://doi.org/10.1016/j.jim.2010.06.005

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Combining T-cell Vaccination and Application of Agonistic Anti-GITR mAb (DTA-1) Induces Complete Eradication of HPV Oncogene Expressing Tumors in Mice

Autor: Corinna Hoffmann, Günter Cichon, Jonas Stanke, Andreas M. Kaufmann, Achim Schneider, Christoph Loddenkemper

Publikováno v: Journal of Immunotherapy. 33:136-145

We generated an adenovirus-based T-cell vaccine (Ad-p14) that reliably elicits T-cell responses to human papillomavirus (HPV) oncogenes of the 2 most common high-risk HPV serotypes. The artificial gene used to create the vaccine comprising 415 aa (12

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d69a52ac93f881da71d627c364e4b4
https://doi.org/10.1097/cji.0b013e3181badc46

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Regulatory (FOXP3+) T cells as target for immune therapy of cervical intraepithelial neoplasia and cervical cancer

Autor: Udo Baron, Harald Stein, Corinna Hoffmann, Sven Olek, Achim Schneider, Christoph Loddenkemper, Andreas M. Kaufmann, Joerg-Peter Ritz, Jochen Huehn, Günter Cichon, Dirk Nagorsen, Jonas Stanke

Publikováno v: Cancer Science. 100:1112-1117

Regulatory (FOXP3+) T cells (Tregs) comprise a subpopulation of CD4+ T cells that suppress autoreactive immune cells, thereby protecting organs and tissues from autoimmunity. Tregs have also been detected in human malignancies and their depletion or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1beabd861050eb88fb141eceb00437f
https://doi.org/10.1111/j.1349-7006.2009.01153.x

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A Dnmt2-like protein mediates DNA methylation inDrosophila

Autor: Jonas Stanke, Frank Lyko, Dirk Stach, Natascha Kunert, Joachim Marhold

Publikováno v: Development. 130:5083-5090

The methylation status of Drosophila DNA has been discussed controversially over a long time. Recent evidence has provided strong support for the existence of 5-methylcytosine in DNA preparations from embryonic stages of fly development. The Drosophi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16619f31edaeee77514ef4203eb4c958
https://doi.org/10.1242/dev.00716

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Creation and characterization of a xenograft model for human cervical cancer

Autor: Corinna, Hoffmann, Christopher, Bachran, Jonas, Stanke, Sefer, Elezkurtaj, Andreas M, Kaufmann, Hendrik, Fuchs, Hendrick, Fuchs, Christoph, Loddenkemper, Achim, Schneider, Günter, Cichon

Publikováno v: Gynecologic oncology. 118(1)

Objective Most of primary human cancer tissues show effective engraftment and proliferation after transplantation onto Scid mice. However xenotransplantation of vital specimens of cervical carcinoma has not been successful in the past, also the gener

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c08f1beb2ae495db7a5432e186ece4b
https://pubmed.ncbi.nlm.nih.gov/20441999

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Corrigendum to 'Creation and characterization of a xenograft model for human cervical cancer' [Gynecologic Oncology 118 (2010) 76–80]

Autor: Hendrik Fuchs, Christopher Bachran, Andreas M. Kaufmann, Sefer Elezkurtaj, Günter Cichon, Corinna Hoffmann, Achim Schneider, Christoph Loddenkemper, Jonas Stanke

Publikováno v: Gynecologic Oncology. 119:604

Corrigendum to “Creation and characterization of a xenograft model for human cervical cancer” [Gynecologic Oncology 118 (2010) 76–80] Corinna Hoffmann , Christopher Bachran , Jonas Stanke , Sefer Elezkurtaj , Andreas M. Kaufmann , Hendrik Fuchs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::da8062a6d8cea3f872dbc7b961d147bf
https://doi.org/10.1016/j.ygyno.2010.08.029

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