Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Jonas S. Erjefält"'
Autor:
Michiko Mori, Carl-Magnus Clausson, Caroline Sanden, Jimmie Jönsson, Cecilia K. Andersson, Premkumar Siddhuraj, Medya Shikhagaie, Karolina Åkesson, Anders Bergqvist, Claes-Göran Löfdahl, Jonas S. Erjefält
Publikováno v:
Journal of Innate Immunity, Pp 1-16 (2022)
Contrasting the antigen-presenting dendritic cells (DCs) in the conducting airways, the alveolar DC populations in human lungs have remained poorly investigated. Consequently, little is known about how alveolar DCs are altered in diseases such as chr
Externí odkaz:
https://doaj.org/article/6fe66d1a35964280b316a4eea1622255
Autor:
Laurits Frøssing, Ditte K. Klein, Morten Hvidtfeldt, Nicolai Obling, Gunilla Telg, Jonas S. Erjefält, Uffe Bodtger, Celeste Porsbjerg
Publikováno v:
ERJ Open Research, Vol 9, Iss 2 (2023)
Background Type 2 (T2) high asthma is recognised as a heterogenous entity consisting of several endotypes; however, the prevalence and distribution of the T2 biomarkers in the general asthma population, across asthma severity, and across compartments
Externí odkaz:
https://doaj.org/article/ae664511f5b442cab827ec26286a8394
Autor:
Lloyd Tanner, Jesper Bergwik, Ravi K. V. Bhongir, Manoj Puthia, Pernilla Lång, Mohamad N. Ali, Charlotte Welinder, Patrik Önnerfjord, Jonas S. Erjefält, Lena Palmberg, Göran Andersson, Arne Egesten
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionDuring airway infection, upregulation of proinflammatory cytokines and subsequent immune cell recruitment is essential to mitigate bacterial infection. Conversely, during prolonged and non-resolving airway inflammation, neutrophils contri
Externí odkaz:
https://doaj.org/article/2ee8d6efa52445b69b6dfca1ea9deb16
Autor:
Jonas S. Erjefält, Natália de Souza Xavier Costa, Jimmie Jönsson, Olga Cozzolino, Katia Cristina Dantas, Carl-Magnus Clausson, Premkumar Siddhuraj, Caroline Lindö, Manar Alyamani, Suzete Cleusa Ferreira Spina Lombardi, Alfredo Mendroni Júnior, Leila Antonangelo, Caroline Silvério Faria, Amaro Nunes Duarte-Neto, Renata Aparecida de Almeida Monteiro, João Renato Rebello Pinho, Michele Soares Gomes-Gouvêa, Roberta Verciano Pereira, Jhonatas Sirino Monteiro, João Carlos Setubal, Ellen Pierre de Oliveira, Jair Theodoro Filho, Caroline Sanden, Jamie M. Orengo, Matthew A. Sleeman, Luiz Fernando Ferraz da Silva, Paulo Hilário Nascimento Saldiva, Marisa Dolhnikoff, Thais Mauad
Publikováno v:
EBioMedicine, Vol 83, Iss , Pp 104229- (2022)
Summary: Background: Severe COVID-19 lung disease exhibits a high degree of spatial and temporal heterogeneity, with different histological features coexisting within a single individual. It is important to capture the disease complexity to support p
Externí odkaz:
https://doaj.org/article/19c5eb08a3f74639b055f0a03c0a2cf5
Autor:
Premkumar Siddhuraj, Jimmie Jönsson, Manar Alyamani, Pavan Prabhala, Mattias Magnusson, Sandra Lindstedt, Jonas S. Erjefält
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundThe mast cell-specific metalloprotease CPA3 has been given important roles in lung tissue homeostasis and disease pathogenesis. However, the dynamics and spatial distribution of mast cell CPA3 expression in lung diseases remain unknown.Meth
Externí odkaz:
https://doaj.org/article/b5251dc1c6f449df8535c21b9ec69627
Autor:
Lloyd Tanner, Jesper Bergwik, Andrew B. Single, Ravi K. V. Bhongir, Jonas S. Erjefält, Arne Egesten
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background and aim: Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease causing irreparable scarring of lung tissue, with most patients succumbing rapidly after diagnosis. The mevalonate pathway, which is involved in the regulation of c
Externí odkaz:
https://doaj.org/article/7030ce1199044af699e4c22048a05f5e
Autor:
David Lamb, Dorothy De Sousa, Karsten Quast, Katrin Fundel-Clemens, Jonas S. Erjefält, Caroline Sandén, Hans Jürgen Hoffmann, Marc Kästle, Ramona Schmid, Kevin Menden, Denis Delic
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-14 (2021)
Abstract Background RORγt is a transcription factor that enables elaboration of Th17-associated cytokines (including IL-17 and IL-22) and is proposed as a pharmacological target for severe asthma. Methods IL-17 immunohistochemistry was performed in
Externí odkaz:
https://doaj.org/article/4625d57e20204c418b1d262620920965
Autor:
Vibeke Backer, Ditte K. Klein, Uffe Bodtger, Kerstin Romberg, Celeste Porsbjerg, Jonas S. Erjefält, Karsten Kristiansen, Ruiqi Xu, Alexander Silberbrandt, Laurits Frøssing, Morten Hvidtfeldt, Nicolai Obling, Linnea Jarenbäck, Abir Nasr, Ellen Tufvesson, Michiko Mori, Matilde Winther-Jensen, Lisa Karlsson, Ulf Nihlén, Thomas Veje Flintegaard, Leif Bjermer
Publikováno v:
European Clinical Respiratory Journal, Vol 7, Iss 1 (2020)
Background: The BREATHE study is a cross-sectional study of real-life patients with asthma and/or COPD in Denmark and Sweden aiming to increase the knowledge across severities and combinations of obstructive airway disease. Design: Patients with susp
Externí odkaz:
https://doaj.org/article/eb34065c2d264af9adb56290a0fe1ac1
Autor:
Medya Mara Shikhagaie, Åsa K. Björklund, Jenny Mjösberg, Jonas S. Erjefält, Anne S. Cornelissen, Xavier Romero Ros, Suzanne M. Bal, Jasper J. Koning, Reina E. Mebius, Michiko Mori, Melanie Bruchard, Bianca Blom, Hergen Spits
Publikováno v:
Cell Reports, Vol 18, Iss 7, Pp 1761-1773 (2017)
Here, we characterize a subset of ILC3s that express Neuropilin1 (NRP1) and are present in lymphoid tissues, but not in the peripheral blood or skin. NRP1+ group 3 innate lymphoid cells (ILC3s) display in vitro lymphoid tissue inducer (LTi) activity.
Externí odkaz:
https://doaj.org/article/aa25019afd43430bba29f05387ad8fb5
Autor:
Premkumar Siddhuraj, Carl-Magnus Clausson, Caroline Sanden, Manar Alyamani, Mohammad Kadivar, Jan Marsal, Joanna Wallengren, Leif Bjermer, Jonas S. Erjefält
Publikováno v:
Cells, Vol 10, Iss 2, p 309 (2021)
The mast cell granule metalloprotease CPA3 is proposed to have important tissue homeostatic functions. However, the basal CPA3 mRNA and protein expression among mast cell populations has remained poorly investigated. Using a novel histology-based met
Externí odkaz:
https://doaj.org/article/5a2dd8db6b124a78ab10f34bb979d477