Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jonas N. Conde"'
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Zika virus (ZIKV) is a mosquito-borne Flavivirus that persistently infects patients; enters protected brain, placental, and testicular compartments; is sexually transmitted; and causes fetal microcephaly in utero. ZIKV persistently infects h
Externí odkaz:
https://doaj.org/article/e1a38e62ea284c6d9cf58f84f02ed407
Autor:
Jonas N. Conde, Grace E. Himmler, Megan C. Mladinich, Yin Xiang Setoh, Alberto A. Amarilla, William R. Schutt, Nicholas Saladino, Elena E. Gorbunova, Daniel J. Salamango, Jorge Benach, Hwan Keun Kim, Erich R. Mackow
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Powassan virus (POWV) is an emerging tick-borne Flavivirus that causes lethal encephalitis and long-term neurologic damage. Currently, there are no POWV therapeutics, licensed vaccines, or reverse genetics systems for producing infectious PO
Externí odkaz:
https://doaj.org/article/f22f350794334089a5acab753f02c7f9
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT Zika virus (ZIKV) is a neurovirulent flavivirus that uniquely causes fetal microcephaly, is sexually transmitted, and persists in patients for up to 6 months. ZIKV persistently infects human brain microvascular endothelial cells (hBMECs) tha
Externí odkaz:
https://doaj.org/article/e2203bc96adf4cccaa9074acf66d0e75
Autor:
Megan C. Mladinich, Grace E. Himmler, Jonas N. Conde, Elena E. Gorbunova, William R. Schutt, Stella Tsirka, Hwan Keun Kim, Erich R. Mackow
Powassan viruses (POWV) are emergent tick-borne flaviviruses that cause severe neurologic disease in humans. Subcutaneous inoculation of C57BL/6 mice with POWV (strain LI9) resulted in overt brain damage resembling spongiform encephalitis. Noting hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::108cc95fbb8f39c430a18fd11a502881
https://doi.org/10.1101/2023.05.11.540417
https://doi.org/10.1101/2023.05.11.540417
Publikováno v:
Methods in Molecular Biology ISBN: 9781071618783
A growing body of evidence demonstrates that endothelial cells (ECs) play a prominent role in immune-enhanced pathology seen in dengue virus (DENV) infection that might contribute to vascular permeability and hemorrhagic manifestations in severe deng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f7c8a82580e00c3b33f2232b4239fba
https://doi.org/10.1007/978-1-0716-1879-0_13
https://doi.org/10.1007/978-1-0716-1879-0_13
Autor:
Jonas N. Conde
Publikováno v:
Methods in Molecular Biology ISBN: 9781071618783
Yeast two-hybrid (Y2H) systems are one of the principal choices for identifying novel binary protein-protein interactions (PPIs). Since its development, it has contributed for the discovery of several PPIs between pathogens and host, allowing not onl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6322dc595bf5426bd95d63957d79a9fd
https://doi.org/10.1007/978-1-0716-1879-0_9
https://doi.org/10.1007/978-1-0716-1879-0_9
Autor:
Jonas N. Conde, Grace Himmler, William R. Schutt, Hwan Keun Kim, Nicholas Saladino, Santiago Sanchez-Vicente, Elena E. Gorbunova, Jorge L. Benach, Erich R. Mackow, Megan C. Mladinich
Publikováno v:
J Virol
Powassan viruses (POWVs) are neurovirulent tick-borne flaviviruses emerging in the Northeastern U.S., with a 2% prevalence in Long Island (LI) deer ticks (Ixodes scapularis). POWVs are transmitted in as little as 15 minutes of a tick bite, and enter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3292be9ab9872c57d3e713de5b458b66
https://doi.org/10.1101/2021.09.30.462684
https://doi.org/10.1101/2021.09.30.462684
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
mBio
mBio
Zika virus (ZIKV) is a neurovirulent flavivirus that uniquely causes fetal microcephaly, is sexually transmitted, and persists in patients for up to 6 months. ZIKV persistently infects human brain microvascular endothelial cells (hBMECs) that form th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd20379bf509055d895feec3261e344
https://doi.org/10.1128/mbio.01962-21
https://doi.org/10.1128/mbio.01962-21
Autor:
Pedro Henrique Carneiro, Richard J. Kuhn, Diego Allonso, Diego R. Coelho, Ronaldo Mohana-Borges, Michael White-Dibiasio, Lucas Mendes-Monteiro, Thu Minh Cao, Iamara da Silva Andrade, Jonas N. Conde
Publikováno v:
J Virol
Dengue is a mosquito-borne infectious disease highly endemic to tropical and subtropical countries. Symptomatic patients can rapidly progress to severe conditions of hemorrhage, plasma extravasation and hypovolemic shock that leads to death. Severe d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df487ed4b054a078b8096c20a6893b1f
https://doi.org/10.1128/jvi.01974-20
https://doi.org/10.1128/jvi.01974-20
Autor:
Leda R. Castilho, Luciana Conde, Alberto Nobrega, Jonas N. Conde, Bruno Maia, Andre M. Vale, Ronaldo Mohana-Borges, Cecilia B. Cavazzoni, Renata G. F. Alvim, Heitor A. Paula Neto, Tostes C V Lucas, Gabriel D. Victora, Iranaia Assunção-Miranda, Rômulo L. S. Neris, Tulio M. Lima, Vicente B. T. Bozza, Diego R. Coelho, Luka Mesin, Jonatan Ersching, Ariën Schiepers
Publikováno v:
The Journal of experimental medicine. 218(9)
Besides antigen-specific responses to viral antigens, humoral immune response in virus infection can generate polyreactive and autoreactive antibodies. Dengue and Zika virus infections have been linked to antibody-mediated autoimmune disorders, inclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::714d76100d14bbec5671e39ba7711872
https://pubmed.ncbi.nlm.nih.gov/34319348
https://pubmed.ncbi.nlm.nih.gov/34319348