Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Jonas Nørskov Søndergaard"'
Autor:
Christian Sommerauer, Carlos J Gallardo-Dodd, Christina Savva, Linnea Hases, Madeleine Birgersson, Rajitha Indukuri, Joanne X Shen, Pablo Carravilla, Keyi Geng, Jonas Nørskov Søndergaard, Clàudia Ferrer-Aumatell, Grégoire Mercier, Erdinc Sezgin, Marion Korach-André, Carl Petersson, Hannes Hagström, Volker M Lauschke, Amena Archer, Cecilia Williams, Claudia Kutter
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 4, Pp 374-402 (2024)
Abstract Sex-based differences in obesity-related hepatic malignancies suggest the protective roles of estrogen. Using a preclinical model, we dissected estrogen receptor (ER) isoform-driven molecular responses in high-fat diet (HFD)-induced liver di
Externí odkaz:
https://doaj.org/article/ee239cfd60044f218b6abfe27eac0000
Autor:
Thuy T. Luu, Jonas Nørskov Søndergaard, Lucía Peña-Pérez, Shabnam Kharazi, Aleksandra Krstic, Stephan Meinke, Laurent Schmied, Nicolai Frengen, Yaser Heshmati, Marcin Kierczak, Thibault Bouderlique, Arnika Kathleen Wagner, Charlotte Gustafsson, Benedict J. Chambers, Adnane Achour, Claudia Kutter, Petter Höglund, Robert Månsson, Nadir Kadri
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Natural killer (NK) cells play roles in viral clearance and early surveillance against malignant transformation, yet our knowledge of the underlying mechanisms controlling their development and functions remain incomplete. To reveal cell fate-determi
Externí odkaz:
https://doaj.org/article/c1dc67fc499e4b4183fc91fffcbae0a1
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2021)
Bile acids (BAs) are detergents essential for intestinal absorption of lipids. Disruption of BA homeostasis can lead to severe liver damage. BA metabolism is therefore under strict regulation by sophisticated feedback mechanisms. The hormone-like pro
Externí odkaz:
https://doaj.org/article/bf1434f27a7b424984f966e3381b9cf2
Autor:
Jonas Nørskov Søndergaard, Simon J. van Heeringen, Maaike W. G. Looman, Chunling Tang, Vassilis Triantis, Pauline Louche, Eva M. Janssen-Megens, Anieta M. Sieuwerts, John W. M. Martens, Colin Logie, Hendrik G. Stunnenberg, Marleen Ansems, Gosse J. Adema
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Dendritic cell (DC)-based immunotherapy makes use of the DC’s ability to direct the adaptive immune response toward activation or inhibition. DCs perform this immune orchestration in part by secretion of selected cytokines. The most potent anti-inf
Externí odkaz:
https://doaj.org/article/ddbaab4a79cd4ec38bc9f51fd0f60db0
Autor:
Jeppe Madura Larsen, Daniel Bisgaard Steen-Jensen, Janne Marie Laursen, Jonas Nørskov Søndergaard, Hanieh Sadat Musavian, Tariq Mahmood Butt, Susanne Brix
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31976 (2012)
Recent studies using culture-independent methods have characterized the human airway microbiota and report microbial communities distinct from other body sites. Changes in these airway bacterial communities appear to be associated with inflammatory l
Externí odkaz:
https://doaj.org/article/65a2169ee5674451902e4aaa0c92da4f
Autor:
Jonas Nørskov Søndergaard, Christian Sommerauer, Ionut Atanasoai, Laura C Hinte, Keyi Geng, Giulia Guiducci, Lars Bräutigam, Myriam Aouadi, Lovorka Stojic, Isabel Barragan, Claudia Kutter
Publikováno v:
Gut. 71:2081-2092
ObjectiveTo better comprehend transcriptional phenotypes of cancer cells, we globally characterised RNA-binding proteins (RBPs) to identify altered RNAs, including long non-coding RNAs (lncRNAs).DesignTo unravel RBP-lncRNA interactions in cancer, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1f4d82fbf398e766ca8a7985cc3b40c
https://doi.org/10.1136/gutjnl-2021-325109
https://doi.org/10.1136/gutjnl-2021-325109
Autor:
Jonas Nørskov Søndergaard, Janyerkye Tulyeu, Ryuya Edahiro, Yuya Shirai, Yuta Yamaguchi, Teruaki Murakami, Takayoshi Morita, Yasuhiro Kato, Haruhiko Hirata, Yoshito Takeda, Daisuke Okuzaki, Shimon Sakaguchi, Atsushi Kumanogoh, Yukinori Okada, James Badger Wing
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Sex-biased humoral immune responses to COVID-19 patients have been observed, but the cellular basis for this is not understood. Using single-cell proteomics by mass cytometry, we find disrupted regulation of humoral immunity in COVID-19 patients, wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ce9d3d552024841a13275c2c268e80e
https://doi.org/10.1073/pnas.2217902120
https://doi.org/10.1073/pnas.2217902120
Autor:
Takehito, Yokoi, Mari, Murakami, Takako, Kihara, Shigeto, Seno, Mitsuru, Arase, James Badger, Wing, Jonas Nørskov, Søndergaard, Ryuichi, Kuwahara, Tomohiro, Minagawa, Eri, Oguro-Igashira, Daisuke, Motooka, Daisuke, Okuzaki, Ryota, Mori, Atsuyo, Ikeda, Yuki, Sekido, Takahiro, Amano, Hideki, Iijima, Keiichi, Ozono, Tsunekazu, Mizushima, Seiichi, Hirota, Hiroki, Ikeuchi, Kiyoshi, Takeda
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 120(1)
T cells differentiate into highly diverse subsets and display plasticity depending on the environment. Although lymphocytes are key mediators of inflammation, functional specialization of T cells in inflammatory bowel disease (IBD) has not been effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f31a34c7e8286a28199d60924528b9a1
https://pubmed.ncbi.nlm.nih.gov/36574662
https://pubmed.ncbi.nlm.nih.gov/36574662
Autor:
Keyi Geng, Lara G. Merino, Linda Wedemann, Aniek Martens, Małgorzata Sobota, Yerma P. Sanchez, Jonas Nørskov Søndergaard, Robert J. White, Claudia Kutter
Publikováno v:
Genome research. 32(10)
The CRISPR-Cas9 system is widely used to permanently delete genomic regions via dual guide RNAs. Genomic rearrangements induced by CRISPR-Cas9 can occur, but continuous technical developments make it possible to characterize complex on-target effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a0959d5f4abe066c7ef5419c92a8b4d
https://pubmed.ncbi.nlm.nih.gov/36180232
https://pubmed.ncbi.nlm.nih.gov/36180232
Autor:
Maaike W. G. Looman, Marleen Ansems, Vassilis Triantis, Renske J.E. van den Bijgaart, Gosse J. Adema, Chunling Tang, Jonas Nørskov Søndergaard
Publikováno v:
Developmental Biology, 463, 2, pp. 101-109
Developmental Biology, 463, 101-109
Developmental Biology, 463, 101-109
Contains fulltext : 220386.pdf (Publisher’s version ) (Open Access) Loss of expression of the transcription regulator DC-SCRIPT (Zfp366) is a prominent prognostic event in estrogen receptor-positive breast cancer patients. Studying the inherent lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd6a6d101b264140c912aa49025fdb84
https://doi.org/10.1016/j.ydbio.2020.05.001
https://doi.org/10.1016/j.ydbio.2020.05.001