Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jonas Muehle"'
Autor:
Ching-Ju Tsai, Jacopo Marino, Ricardo Adaixo, Filip Pamula, Jonas Muehle, Shoji Maeda, Tilman Flock, Nicholas MI Taylor, Inayatulla Mohammed, Hugues Matile, Roger JP Dawson, Xavier Deupi, Henning Stahlberg, Gebhard Schertler
Publikováno v:
eLife, Vol 8 (2019)
One of the largest membrane protein families in eukaryotes are G protein-coupled receptors (GPCRs). GPCRs modulate cell physiology by activating diverse intracellular transducers, prominently heterotrimeric G proteins. The recent surge in structural
Externí odkaz:
https://doaj.org/article/e771e8ad582e45b493b49c84fa5cd9a3
Autor:
Tobias Weinert, Steffen Bruenle, Tim Tetaz, Przemyslaw Nogly, Andreas Kuglstatter, Alain Gast, Jean-Marie Vonach, Antonia Furrer, Joerg Standfuss, Chia-Ying Huang, Jonas Muehle, Daniel Mattle, Kathrin Jaeger, Noemi Haenggi, Takuya Miyazaki, Roger J. P. Dawson, Joerg Benz, Martin Weber, Wolfgang Guba, Markus G. Rudolph
Publikováno v:
Cell
Cell, 178 (5)
Cell, 178 (5)
Summary The CC chemokine receptor 7 (CCR7) balances immunity and tolerance by homeostatic trafficking of immune cells. In cancer, CCR7-mediated trafficking leads to lymph node metastasis, suggesting the receptor as a promising therapeutic target. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28a91b1d91b07c85b130b9ef54eb1c38
https://pubmed.ncbi.nlm.nih.gov/31442409
https://pubmed.ncbi.nlm.nih.gov/31442409