Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jonas M. la Cour"'
Autor:
Jonas M la Cour, Pernille Winding Gojkovic, Sophie E B Ambjørner, Jonas Bagge, Simone M Jensen, Svetlana Panina, Martin W Berchtold
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204520 (2018)
The calcium binding protein ALG-2 is upregulated in several types of cancerous tissues and cancer cell death may be a consequence of ALG-2 downregulation. Novel research suggests that ALG-2 is involved in membrane repair mechanisms, in line with seve
Externí odkaz:
https://doaj.org/article/6b0f49f98dfd4383996f07061f2f3797
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75309 (2013)
Coated vesicles mediate the traffic of secretory and membrane cargo proteins from the endoplasmic reticulum (ER) to the Golgi apparatus. The coat protein complex (COPII) involved in vesicle budding is constituted by a GTPase, Sar1, the inner coat com
Externí odkaz:
https://doaj.org/article/b18a7ee655d74d1b868639d63ca8ef2d
Autor:
Martin W. Berchtold, Thomas Jespersen, Jonas M. la Cour, Kalai Mangai Muthukumarasamy, Arnela Saljic, Kim Boddum, Morten Grunnet
Publikováno v:
Physiological Reports, Vol 7, Iss 19, Pp n/a-n/a (2019)
Saljic, A, Muthukumarasamy, K M, la Cour, J M, Boddum, K, Grunnet, M, Berchtold, M W & Jespersen, T 2019, ' Impact of arrhythmogenic calmodulin variants on small conductance Ca 2+-activated K + (SK3) channels ', Physiological Reports, vol. 7, no. 19, e14210 . https://doi.org/10.14814/phy2.14210
Saljic, A, Muthukumarasamy, K M, la Cour, J M, Boddum, K, Grunnet, M, Berchtold, M W & Jespersen, T 2019, ' Impact of arrhythmogenic calmodulin variants on small conductance Ca 2+-activated K + (SK3) channels ', Physiological Reports, vol. 7, no. 19, e14210 . https://doi.org/10.14814/phy2.14210
Calmodulin (CaM) is a ubiquitous Ca2+‐sensing protein regulating many important cellular processes. Several CaM‐associated variants have been identified in a small group of patients with cardiac arrhythmias. The mechanism remains largely unknown,
Autor:
Martin W. Berchtold, Lasse G. Lorentzen, Isabel Porth, Martin R. Larsen, Katarzyna Kulej, Jonas M. la Cour, Triantafyllos Zacharias, S. B. Panina, Mads Munk
Publikováno v:
Berchtold, M W, Munk, M, Kulej, K, Porth, I, Lorentzen, L, Panina, S, Zacharias, T, Larsen, M R & la Cour, J M 2021, ' The heart arrhythmia-linked D130G calmodulin mutation causes premature inhibitory autophosphorylation of CaMKII ', Biochimica et Biophysica Acta-Molecular Cell Research, vol. 1868, no. 12, 119119 . https://doi.org/10.1016/j.bbamcr.2021.119119
The Ca2+/calmodulin (CaM)-dependent kinase II (CaMKII) is well known for transmitting Ca2+-signals, which leads to a multitude of physiological responses. Its functionality is believed to involve CaMKII holoenzyme dynamics where trans-autophosphoryla
Autor:
Sophie E. B. Ambjørner, S. B. Panina, Martin W. Berchtold, Pernille Winding Gojkovic, Simone M. Jensen, Jonas Bagge, Jonas M. la Cour
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204520 (2018)
la Cour, J M, Gojkovic, P W, Ambjorner, S E B, Bagge, J, Jensen, S M, Panina, S & Berchtold, M W 2018, ' ALG-2 participates in recovery of cells after plasma membrane damage by electroporation and digitonin treatment ', PLOS ONE, vol. 13, no. 9, e0204520, pp. 1-13 . https://doi.org/10.1371/journal.pone.0204520
PLoS ONE
la Cour, J M, Gojkovic, P W, Ambjorner, S E B, Bagge, J, Jensen, S M, Panina, S & Berchtold, M W 2018, ' ALG-2 participates in recovery of cells after plasma membrane damage by electroporation and digitonin treatment ', PLOS ONE, vol. 13, no. 9, e0204520, pp. 1-13 . https://doi.org/10.1371/journal.pone.0204520
PLoS ONE
The calcium binding protein ALG-2 is upregulated in several types of cancerous tissues and cancer cell death may be a consequence of ALG-2 downregulation. Novel research suggests that ALG-2 is involved in membrane repair mechanisms, in line with seve
Autor:
Thomas Jespersen, Jau-Nian Chen, Katarzyna Kulej, Raffaela Torggler, Martin R. Larsen, Jonas M. la Cour, Triantafyllos Zacharias, Kevin Wang, Martin W. Berchtold
Publikováno v:
Berchtold, M W, Zacharias, T, Kulej, K, Wang, K, Torggler, R, Jespersen, T, Chen, J-N, Larsen, M R & la Cour, J M 2016, ' The arrhythmogenic calmodulin mutation D129G dysregulates cell growth, calmodulin-dependent kinase II activity, and cardiac function in zebrafish ', Journal of Biological Chemistry, vol. 291, no. 52, pp. 26636-26646 . https://doi.org/10.1074/jbc.M116.758680
The Journal of biological chemistry, vol 291, iss 52
The Journal of biological chemistry, vol 291, iss 52
Calmodulin (CaM) is a Ca(2+) binding protein modulating multiple targets, several of which are associated with cardiac pathophysiology. Recently, CaM mutations were linked to heart arrhythmia. CaM is crucial for cell growth and viability, yet the eff
Autor:
Amandeep Kaur, Hongbing Li, Jonas M. la Cour, Antonio Villalobo, Svetlana Panina, Martin W. Berchtold, María José Ruano, Pablo Sánchez-González, Uffe H. Olesen, Alexander Stephan
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
et al.
Calmodulin (CaM) is the major component of calcium signaling pathways mediating the action of various effectors. Transient increases in the intracellular calcium level triggered by a variety of stimuli lead to the formation of Ca2+/CaM co
Calmodulin (CaM) is the major component of calcium signaling pathways mediating the action of various effectors. Transient increases in the intracellular calcium level triggered by a variety of stimuli lead to the formation of Ca2+/CaM co
Publikováno v:
Biochemical and Biophysical Research Communications. 378:145-148
ALG-2 (apoptosis-linked gene-2 encoded protein) has been shown to be upregulated in a variety of human tumors questioning its previously assumed pro-apoptotic function. The aim of the present study was to obtain insights into the role of ALG-2 in hum
Autor:
Jonas M. la Cour, Svetlana Tarabykina, Pernille Winding, Martin W. Berchtold, Maxwell Sehested, Jens Mollerup
Publikováno v:
The American Journal of Pathology. 163:81-89
ALG-2 was isolated in a screen for proteins involved in programmed cell death and is the first Ca(2+)-binding protein found to be directly involved in apoptosis. We have generated polyclonal antibodies that are suitable for detecting ALG-2 using diff
Autor:
Pablo Sánchez-González, Antonio Villalobo, Line K. Kallerup, Uffe H. Olesen, Svetlana Panina, Kristoffer V. K. Knudsen, Martin W. Berchtold, Rasita Bumbuleviciute, Jonas M. la Cour, Alexander Stephan, Kivin Jacobsen
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
et al.
Calmodulin (CaM) was shown to be essential for survival of lower eukaryotes by gene deletion experiments. So far, no CaM gene deletion was reported in higher eukaryotes. In vertebrates, CaM is expressed from several genes, which encode an
Calmodulin (CaM) was shown to be essential for survival of lower eukaryotes by gene deletion experiments. So far, no CaM gene deletion was reported in higher eukaryotes. In vertebrates, CaM is expressed from several genes, which encode an