Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jonas M. Will"'
Publikováno v:
Analytical Chemistry. 93:878-885
A fast and fully automated method for chiral analysis has been developed by combining a chiral derivatization approach with high-resolution trapped ion mobility separation. Although the presented approach can be potentially applied to diverse types o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee1f5f7ad04c825fb0093bbfc6bbef1
https://doi.org/10.1021/acs.analchem.0c03481
https://doi.org/10.1021/acs.analchem.0c03481
Autor:
Nico Bückreiß, Mikhail A. Panteleev, Maximilian Barth, Benjamin M Wenzel, Gregor A Kastner, Antti Poso, Svetlana A. Kalinina, Hans-Ulrich Humpf, Ruzanna A. Ovsepyan, Uwe Karst, Lukas Imberg, Marvin Korff, Dmitrii V. Kalinin, Constantin G. Daniliuc, Kirill R Butov, Matthias Lehr, Jonas M. Will, Gerd Bendas, Torsten Steinmetzer
Publikováno v:
Journal of Medicinal Chemistry. 63:13159-13186
We herein report the conventional and microscale parallel synthesis of selective inhibitors of human blood coagulation factor XIIa and thrombin exhibiting a 1,2,4-triazol-5-amine scaffold. Structural variations of this scaffold allowed identifying de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a122dda2d0c15b0636be36a9342770d6
https://doi.org/10.1021/acs.jmedchem.0c01635
https://doi.org/10.1021/acs.jmedchem.0c01635
Autor:
Ilker Balicioglu, Lukas Imberg, Constantin G. Daniliuc, Marvin Korff, Simon Platte, Jonas M. Will, Catharina Erbacher, Uwe Karst, Dmitrii V. Kalinin
Publikováno v:
ChemMedChem. 16(24)
Herein we report a microscale parallel synthetic approach allowing for rapid access to libraries of N-acylated aminotriazoles and screening of their inhibitory activity against factor XIIa (FXIIa) and thrombin, which are targets for antithrombotic dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12157967ac9c59f6506ab2679435e282
https://pubmed.ncbi.nlm.nih.gov/34278727
https://pubmed.ncbi.nlm.nih.gov/34278727
Autor:
Marvin, Korff, Lukas, Imberg, Jonas M, Will, Nico, Bückreiß, Svetlana A, Kalinina, Benjamin M, Wenzel, Gregor A, Kastner, Constantin G, Daniliuc, Maximilian, Barth, Ruzanna A, Ovsepyan, Kirill R, Butov, Hans-Ulrich, Humpf, Matthias, Lehr, Mikhail A, Panteleev, Antti, Poso, Uwe, Karst, Torsten, Steinmetzer, Gerd, Bendas, Dmitrii V, Kalinin
Publikováno v:
Journal of medicinal chemistry. 63(21)
We herein report the conventional and microscale parallel synthesis of selective inhibitors of human blood coagulation factor XIIa and thrombin exhibiting a 1,2,4-triazol-5-amine scaffold. Structural variations of this scaffold allowed identifying de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::236ea7e65cf60370817ad687af9e4c77
https://pubmed.ncbi.nlm.nih.gov/33089691
https://pubmed.ncbi.nlm.nih.gov/33089691
Publikováno v:
Metallomics : integrated biometal science. 12(11)
In this study, the combination of speciation analysis and native mass spectrometry is presented as a powerful tool to gain new insight into the diverse interactions of environmentally relevant organotin compounds (OTCs) with proteins. Analytical stan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3eff386aae1db88c3e3c8307bf662d8
https://pubmed.ncbi.nlm.nih.gov/32930317
https://pubmed.ncbi.nlm.nih.gov/32930317
Autor:
Simon Platte, Marvin Korff, Lukas Imberg, Ilker Balicioglu, Catharina Erbacher, Jonas M. Will, Constantin G. Daniliuc, Uwe Karst, Dmitrii V. Kalinin
Publikováno v:
ChemMedChem. 16:3627-3627
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7f48fbf74023afd4c19b5db62eb44d1
https://doi.org/10.1002/cmdc.202100741
https://doi.org/10.1002/cmdc.202100741