Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jonas J. W. Kuiper"'
Autor:
Pulak R. Nath, Mary Maclean, Vijay Nagarajan, Jung Wha Lee, Mehmet Yakin, Aman Kumar, Hadi Nadali, Brian Schmidt, Koray D. Kaya, Shilpa Kodati, Alice Young, Rachel R. Caspi, Jonas J. W. Kuiper, H. Nida Sen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Birdshot chorioretinopathy is an inflammatory eye condition strongly associated with MHC-I allele HLA-A29. The striking association with MHC-I suggests involvement of T cells, whereas natural killer (NK) cell involvement remains largely unst
Externí odkaz:
https://doaj.org/article/f81206102c384d35a8236de3f769aa55
Publikováno v:
Journal of Ophthalmic Inflammation and Infection, Vol 13, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/ff25544e401041e2939459b7014f2e2d
Autor:
Wouter J. Venema, Sanne Hiddingh, Joke H. de Boer, Frans H. J. Claas, Arend Mulder, Anneke I. den Hollander, Efstratios Stratikos, Siranush Sarkizova, Lars T. van der Veken, George M. C. Janssen, Peter A. van Veelen, Jonas J. W. Kuiper
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Birdshot Uveitis (BU) is a blinding inflammatory eye condition that only affects HLA-A29-positive individuals. Genetic association studies linked ERAP2 with BU, an aminopeptidase which trims peptides before their presentation by HLA class I at the ce
Externí odkaz:
https://doaj.org/article/96774bd91fe94255b5f0907aab6bb0ce
Autor:
Jonas J. W. Kuiper, Wouter J. Venema
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
HLA class I alleles constitute established risk factors for non-infectious uveitis and preemptive genotyping of HLA class I alleles is standard practice in the diagnostic work-up. The HLA-A29 serotype is indispensable to Birdshot Uveitis (BU) and ren
Externí odkaz:
https://doaj.org/article/7dd0282bb2c04ef0ba7043c2ea422ea8
Autor:
Roos A. W. Wennink, Aridaman Pandit, Anne-Mieke J. W. Haasnoot, Sanne Hiddingh, Viera Kalinina Ayuso, Nico M. Wulffraat, Bas J. Vastert, Timothy R. D. J. Radstake, Joke H. de Boer, Jonas J. W. Kuiper
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
PurposePatients with juvenile idiopathic arthritis (JIA) are prone to developing chronic anterior uveitis (JIA-U+). Although several risk factors for JIA-U+ have been identified, the underlying etiology is poorly understood. Histopathological studies
Externí odkaz:
https://doaj.org/article/798a79d0191346309a8ded76b587a23f
Autor:
Fleurieke H. Verhagen, Sanne Hiddingh, Rianne Rijken, Aridaman Pandit, Emmerik Leijten, Michel Olde Nordkamp, Ninette H. ten Dam-van Loon, Stefan Nierkens, Saskia M. Imhof, Joke H. de Boer, Timothy R. D. J. Radstake, Jonas J. W. Kuiper
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Background: Non-infectious uveitis (NIU) is a severe intra ocular inflammation, which frequently requires prompt systemic immunosuppressive therapy (IMT) to halt the development of vision-threatening complications. IMT is considered when NIU cannot b
Externí odkaz:
https://doaj.org/article/2bf4075200f2421d96614479395ebbc5
Autor:
Pulak R. Nath, Mary Maclean, Vijay Nagarajan, Jung Wha Lee, Mehmet Yakin, Aman Kumar, Hadi Nadali, Brian Schmidt, Koray D. Kaya, Shilpa Kodati, Alice Young, Rachel R. Caspi, Jonas J. W. Kuiper, H. Nida Sen
Birdshot chorioretinopathy uveitis (BCR-UV) is strongly associated with HLA-A29 which implicates MHC-I pathway mediated perturbation of natural killer (NK) cells as a potential disease mechanism. We profiled blood NK cells at single-cell resolution i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aaed4cf68454f69af2086880c225e87d
https://doi.org/10.1101/2022.09.11.22279821
https://doi.org/10.1101/2022.09.11.22279821
Autor:
Roos A. W. Wennink, Viera Kalinina Ayuso, Weiyang Tao, Eveline M. Delemarre, Joke H. de Boer, Jonas J. W. Kuiper
Publikováno v:
Translational vision sciencetechnology. 11(2)
To identify a serum biomarker signature that can help predict response to conventional synthetic disease-modifying antirheumatic drug (csDMARD) therapy in pediatric noninfectious uveitis.In this case-control cohort study, we performed a 368-plex prot
Autor:
Anne-Mieke J W, Haasnoot, Jonas J W, Kuiper, Sanne, Hiddingh, Peter A W J F, Schellekens, Wilco, de Jager, Saskia M, Imhof, Timothy R D J, Radstake, Joke H, de Boer
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 68(7)
Childhood uveitis is a vision-threatening inflammatory eye disease commonly attributed to juvenile idiopathic arthritis (JIA). The pathogenesis is poorly understood, which makes clinical management challenging. We analyzed soluble mediators in ocular