Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jonas Hyld, Steffen"'
Structural and functional analysis of aquaporin-2 mutants involved in nephrogenic diabetes insipidus
Autor:
Carl Johan Hagströmer, Jonas Hyld Steffen, Stefan Kreida, Tamim Al-Jubair, Anna Frick, Pontus Gourdon, Susanna Törnroth-Horsefield
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Aquaporins are water channels found in the cell membrane, where they allow the passage of water molecules in and out of the cells. In the kidney collecting duct, arginine vasopressin-dependent trafficking of aquaporin-2 (AQP2) fine-tunes rea
Externí odkaz:
https://doaj.org/article/e8396a28c8e042f783b0a842ff88dc15
Autor:
Jianfei He, Jonas Hyld Steffen, Peter Waaben Thulstrup, Jannik Nedergaard Pedersen, Max B. Sauerland, Daniel E. Otzen, Clare L. Hawkins, Pontus Gourdon, Michael J. Davies, Per Hägglund
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Anastellin, a recombinant protein fragment from the first type III module of fibronectin, mimics a partially unfolded intermediate implicated in the assembly of fibronectin fibrils. Anastellin influences the structure of fibronectin and init
Externí odkaz:
https://doaj.org/article/d47b5504ab4a45aeadebb6822af4b254
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 9, p e1010074 (2022)
ATP7B is a human copper-transporting P1B-type ATPase that is involved in copper homeostasis and resistance to platinum drugs in cancer cells. ATP7B consists of a copper-transporting core and a regulatory N-terminal tail that contains six metal-bindin
Externí odkaz:
https://doaj.org/article/dfc64b50a4dd459b9314d987f2ed7825
Autor:
Jonas Hyld Steffen, Julie Winkel Missel, Tamim Al-Jubair, Philip Kitchen, Mootaz M. Salman, Roslyn M. Bill, Susanna Törnroth-Horsefield, Pontus Gourdon
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101312- (2022)
Summary: Aquaporins (AQPs) are water channels embedded in the cell membrane that are critical in maintaining water homeostasis. We describe a protocol for determining the water permeation capacity of AQPs reconstituted into proteoliposomes. Using a s
Externí odkaz:
https://doaj.org/article/1a3eb367bcee4d1c9d47e268d3434edd
Autor:
Tamim Al-Jubair, Jonas Hyld Steffen, Julie Winkel Missel, Philip Kitchen, Mootaz M. Salman, Roslyn M. Bill, Pontus Gourdon, Susanna Törnroth-Horsefield
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101298- (2022)
Summary: Aquaporins (AQPs) are membrane-bound water channels that play crucial roles in maintaining the water homeostasis of the human body. Here, we present a protocol for high-yield recombinant expression of human AQPs in the methylotropic yeast Pi
Externí odkaz:
https://doaj.org/article/5ab3c0de13584bbd895ba84cf305b169
Autor:
Tamim Al-Jubair, Jonas Hyld Steffen, Julie Winkel Missel, Philip Kitchen, Mootaz M. Salman, Roslyn M. Bill, Pontus Gourdon, Susanna Törnroth-Horsefield
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101316- (2022)
Summary: Aquaporin water channels (AQPs) are membrane proteins that maintain cellular water homeostasis. The interactions between human AQPs and other proteins play crucial roles in AQP regulation by both gating and trafficking. Here, we describe a p
Externí odkaz:
https://doaj.org/article/cd7e6ed9d36d4404b5a0e95d3eb6b738
Autor:
Julie Winkel Missel, Nina Salustros, Eva Ramos Becares, Jonas Hyld Steffen, Amalie Gerdt Laursen, Angelica Struve Garcia, Maria M. Garcia-Alai, Čeněk Kolar, Pontus Gourdon, Kamil Gotfryd
Publikováno v:
Current Research in Structural Biology, Vol 3, Iss , Pp 85-94 (2021)
Membrane proteins (MPs) constitute a large fraction of the proteome, but exhibit physicochemical characteristics that impose challenges for successful sample production crucial for subsequent biophysical studies. In particular, MPs have to be extract
Externí odkaz:
https://doaj.org/article/52c903b70c7b4014836baa03b5bbc555
Autor:
Anders, Wiuf, Jonas Hyld, Steffen, Eva Ramos, Becares, Christina, Grønberg, Dhani Ram, Mahato, Søren G F, Rasmussen, Magnus, Andersson, Tristan, Croll, Kamil, Gotfryd, Pontus, Gourdon
Publikováno v:
Science advances. 8(28)
Zinc is essential for all organisms and yet detrimental at elevated levels. Hence, homeostasis of this metal is tightly regulated. The Zrt/Irt-like proteins (ZIPs) represent the only zinc importers in metazoans. Mutations in human ZIPs cause serious
Autor:
Angelica Struve Garcia, Eva Ramos Becares, Maria M. Garcia-Alai, Jonas Hyld Steffen, Amalie Gerdt Laursen, Kamil Gotfryd, Čeněk Kolar, Julie Winkel Missel, Pontus Gourdon, Nina Salustros
Publikováno v:
Missel, J W, Salustros, N, Becares, E R, Steffen, J H, Laursen, A G, Garcia, A S, Garcia-Alai, M M, Kolar, C, Gourdon, P & Gotfryd, K 2021, ' Cyclohexyl-alpha maltoside as a highly efficient tool for membrane protein studies ', Current Research in Structural Biology, vol. 3, pp. 85-94 . https://doi.org/10.1016/j.crstbi.2021.03.002
Current Research in Structural Biology
Current Research in Structural Biology, Vol 3, Iss, Pp 85-94 (2021)
Current Research in Structural Biology
Current Research in Structural Biology, Vol 3, Iss, Pp 85-94 (2021)
Membrane proteins (MPs) constitute a large fraction of the proteome, but exhibit physicochemical characteristics that impose challenges for successful sample production crucial for subsequent biophysical studies. In particular, MPs have to be extract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::941963255f68fd52a1dfe455d8f5d86e
https://curis.ku.dk/ws/files/291023487/Cyclohexyl_maltoside_as_a_highly_efficient_tool_for_membrane.pdf
https://curis.ku.dk/ws/files/291023487/Cyclohexyl_maltoside_as_a_highly_efficient_tool_for_membrane.pdf