Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jonas Goretzko"'
Autor:
Jonas Goretzko, Inga Pauels, Nicole Heitzig, Katharina Thomas, Marina Kardell, Johannes Naß, Einar Kleinhans Krogsaeter, Sebastian Schloer, Barbara Spix, Anna Lívia Linard Matos, Charlotte Leser, Tristan Wegner, Frank Glorius, Franz Bracher, Volker Gerke, Jan Rossaint, Christian Grimm, Ursula Rescher
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113501- (2023)
Summary: Upon proinflammatory challenges, endothelial cell surface presentation of the leukocyte receptor P-selectin, together with the stabilizing co-factor CD63, is needed for leukocyte capture and is mediated via demand-driven exocytosis from the
Externí odkaz:
https://doaj.org/article/743e166b584b4ba9a9ee505a123e92b3
Autor:
Susann Kummer, Angelika Lander, Jonas Goretzko, Norman Kirchoff, Ursula Rescher, Sebastian Schloer
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 195-207 (2022)
Ebola virus disease (EVD) is a severe and frequently lethal disease caused by Ebola virus (EBOV). The latest occasional EVD outbreak (2013–2016) in Western African, which was accompanied by a high fatality rate, showed the great potential of epidem
Externí odkaz:
https://doaj.org/article/673fa9eaf29b4e8e97536ec71e50e379
Autor:
Sebastian Schloer, Linda Brunotte, Jonas Goretzko, Angeles Mecate-Zambrano, Nadia Korthals, Volker Gerke, Stephan Ludwig, Ursula Rescher
Publikováno v:
Emerging Microbes and Infections, Vol 9, Iss 1, Pp 2245-2255 (2020)
ABSTRACTThe Coronavirus Disease 2019 (COVID-19) pandemic caused by the Severe Acute Respiratory Syndrome Related Coronavirus 2 (SARS-CoV-2) is a global health emergency. As only very limited therapeutic options are clinically available, there is an u
Externí odkaz:
https://doaj.org/article/bcf82b4bf73a42dcb504646c60eb279b
Autor:
Sebastian Schloer, Jonas Goretzko, Alexander Kühnl, Linda Brunotte, Stephan Ludwig, Ursula Rescher
Publikováno v:
Emerging Microbes and Infections, Vol 8, Iss 1, Pp 80-93 (2019)
ABSTRACTInfluenza A virus (IAV) is a common pathogen of respiratory disease. The IAV-induced seasonal epidemics and the sporadic pandemics are associated with high morbidity and mortality. Therefore, effective protection and therapy for IAV infection
Externí odkaz:
https://doaj.org/article/30def7bef94a4af185c7a339cd4abadd
Publikováno v:
Pharmaceuticals, Vol 15, Iss 2, p 212 (2022)
Because of their epidemic and pandemic potential, emerging viruses are a major threat to global healthcare systems. While vaccination is in general a straightforward approach to prevent viral infections, immunization can also cause escape mutants tha
Externí odkaz:
https://doaj.org/article/d4d37ee2f94a41cc83fe5b372f987012
Autor:
Susann Herzog, Felix Dach, Nicole de Buhr, Silke Niemann, Jannik Schlagowski, Diego Chaves-Moreno, Claudia Neumann, Jonas Goretzko, Vera Schwierzeck, Alexander Mellmann, Angelika Dübbers, Peter Küster, Holger Schültingkemper, Ursula Rescher, Dietmar H. Pieper, Maren von Köckritz-Blickwede, Barbara C. Kahl
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Staphylococcus aureus is one of the first and most prevalent pathogens cultured from the airways of cystic fibrosis (CF) patients, which can persist there for extended periods. Airway infections in CF patients are characterized by a strong inflammato
Externí odkaz:
https://doaj.org/article/d2bcd5f29662432aad134ee62a51d8fe
Publikováno v:
Viruses, Vol 12, Iss 7, p 703 (2020)
Influenza virus infections and their associated morbidity and mortality are a major threat to global health. Vaccination is an effective influenza prevention measure; however, the effectiveness is challenged by the rapid changes in the influenza viru
Externí odkaz:
https://doaj.org/article/62f9580c45304b9bbf68cacee7b704da
Publikováno v:
Pharmaceuticals (Basel, Switzerland). 15(2)
Because of their epidemic and pandemic potential, emerging viruses are a major threat to global healthcare systems. While vaccination is in general a straightforward approach to prevent viral infections, immunization can also cause escape mutants tha
Autor:
J. Rossaint, A. L. Linard Matos, Volker Gerke, Frank Glorius, Sebastian Schloer, Jonas Goretzko, Franz Bracher, Ursula Rescher, Tristan Wegner, Nicole Heitzig, J. Nass, Einar Krogsaeter, Christian Grimm, K. Thomas
In response to pro-inflammatory challenges including pathogenic attack and tissue damage, the endothelial cell surface is rearranged to present leukocyte-engaging cell surface receptors. The initial contact needed for leukocyte tethering and rolling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::959cc13ab58b4f1ae050375e54030f4c
https://doi.org/10.1101/2021.09.28.462104
https://doi.org/10.1101/2021.09.28.462104
Autor:
Petra Jakobs, Uwe Kirchhefer, Dominique Manikowski, Kay Grobe, Jurij Froese, Kristina Ehring, Jonas Goretzko, Fabian Gude, Ursula Rescher
Publikováno v:
Journal of Cell Science
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The Sonic hedgehog (Shh) pathway controls embryonic development and tissue homeostasis after birth. Long-standing questions about this pathway include how the dual-lipidated, firmly plasma membrane-associated Shh ligand is released from producing cel