Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Jonas Franz"'
Autor:
Nathalie A. Lengacher, Julianna J. Tomlinson, Ann-Kristin Jochum, Jonas Franz, Omar Hasan Ali, Lukas Flatz, Wolfram Jochum, Josef Penninger, aSCENT-PD Investigators, Christine Stadelmann, John M. Woulfe, Michael G. Schlossmacher
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract The majority of patients with Parkinson disease (PD) experience a loss in their sense of smell and accumulate insoluble α-synuclein aggregates in their olfactory bulbs (OB). Subjects affected by a SARS-CoV-2-linked illness (COVID-19) also f
Externí odkaz:
https://doaj.org/article/55e9314822274d27aa985e4800b41313
Autor:
Matthias Kettwig, Katharina Ternka, Kristin Wendland, Dennis Manfred Krüger, Silvia Zampar, Charlotte Schob, Jonas Franz, Abhishek Aich, Anne Winkler, M. Sadman Sakib, Lalit Kaurani, Robert Epple, Hauke B. Werner, Samy Hakroush, Julia Kitz, Marco Prinz, Eva Bartok, Gunther Hartmann, Simone Schröder, Peter Rehling, Marco Henneke, Susann Boretius, A. Alia, Oliver Wirths, Andre Fischer, Christine Stadelmann, Stefan Nessler, Jutta Gärtner
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Studies on interferon-driven brain pathology have so far been hampered by the lack of appropriate animal models. Here the authors characterize RNASET2-deficient mice and show that neuroinflammation and brain atrophy are IFNAR1-dependent.
Externí odkaz:
https://doaj.org/article/bd1fa646273840d68762f26fc8a37047
Autor:
Melanie Lohrberg, Anne Winkler, Jonas Franz, Franziska van der Meer, Torben Ruhwedel, Nikoloz Sirmpilatze, Rakshit Dadarwal, Ronja Handwerker, Daniel Esser, Kerstin Wiegand, Christian Hagel, Andreas Gocht, Fatima Barbara König, Susann Boretius, Wiebke Möbius, Christine Stadelmann, Alonso Barrantes-Freer
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-24 (2020)
Abstract Demyelinated lesions in human pons observed after osmotic shifts in serum have been referred to as central pontine myelinolysis (CPM). Astrocytic damage, which is prominent in neuroinflammatory diseases like neuromyelitis optica (NMO) and mu
Externí odkaz:
https://doaj.org/article/918549fd508a43c99de49fff73f22fe0
Autor:
Désirée Tampe, Samy Hakroush, Mark-Sebastian Bösherz, Jonas Franz, Heike Hofmann-Winkler, Stefan Pöhlmann, Stefan Kluge, Onnen Moerer, Christine Stadelmann, Philipp Ströbel, Martin Sebastian Winkler, Björn Tampe
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Background: Acute kidney injury (AKI) is very common in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) disease 2019 (COVID-19) and considered as a risk factor for COVID-19 severity. SARS-CoV-2 renal tropism has been observed in COVID-19
Externí odkaz:
https://doaj.org/article/d537298a0e3d4c4fa18d47340fc87d2c
Autor:
Fabian Maass, Philipp von Gottberg, Jonas Franz, Christine Stadelmann, Mathias Bähr, Martin S. Weber
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Fingolimod represents a highly effective disease-modifying drug in patients with active relapsing-remitting multiple sclerosis (RRMS). Its immunosuppressive effects can mediate adverse events like increased risk of cancer development or appearance of
Externí odkaz:
https://doaj.org/article/dbbfd4dc4c604d61b2f27676f62413ca
Autor:
Michael Bartl, Mohammed Dakna, Douglas Galasko, Samantha J Hutten, Tatiana Foroud, Marian Quan, Kenneth Marek, Andrew Siderowf, Jonas Franz, Claudia Trenkwalder, Brit Mollenhauer, Parkinson’s Progression Markers Initiative
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0257372 (2021)
AimSeveral pathophysiological processes are involved in Parkinson's disease (PD) and could inform in vivo biomarkers. We assessed an established biomarker panel, validated in Alzheimer's Disease, in a PD cohort.MethodsLongitudinal cerebrospinal fluid
Externí odkaz:
https://doaj.org/article/2dd6276ca17c4e6e850a0ed593e32cff
Autor:
Jonas Franz, Benjamin F Brinkmann, Michael König, Jana Hüve, Christian Stock, Klaus Ebnet, Christoph Riethmüller
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146598 (2016)
Endothelial barriers have a central role in inflammation as they allow or deny the passage of leukocytes from the vasculature into the tissue. To bind leukocytes, endothelial cells form adhesive clusters containing tetraspanins and ICAM-1, so-called
Externí odkaz:
https://doaj.org/article/32439498e7e7483c91682c335348a9da
Autor:
Josefine Radke, Jenny Meinhardt, Tom Aschman, Robert Lorenz Chua, Vadim Farztdinov, Sören Lukkassen, Foo Wei Ten, Ekaterina Friebel, Naveed Ishaque, Jonas Franz, Valerie Helena Huhle, Ronja Mothes, Kristin Peters, Carolina Thomas, Simon Streit, Regina von Manitius, Péter Körtvélyessy, Stefan Vielhaber, Dirk Reinhold, Anja Hauser, Anja Osterloh, Philipp Enghard, Jana Ihlow, Sefer Elezkurtaj, David Horst, Florian Kurth, Marcel A. Müller, Nils C. Gassen, Julia Schneider, Katharina Jechow, Bernd Timmermann, Camila Fernandez-Zapata, Chotima Böttcher, Werner Stenzel, Emanuel Wyler, Victor Corman, Christine Stadelmann-Nessler, Markus Ralser, Roland Eils, Frank L. Heppner, Michael Mülleder, Christian Conrad, Helena Radbruch
In COVID-19 neurological alterations are noticed during the systemic viral infection. Various pathophysiological mechanisms on the central nervous system (CNS) have been suggested in the past two years, including the viral neurotropism hypothesis. Ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24c5414abe1f7853a3ba61674136c250
https://doi.org/10.1101/2023.01.16.22283804
https://doi.org/10.1101/2023.01.16.22283804
Autor:
Anne Winkler, Jonas Franz, Marco Henneke, Andre Fischer, Peter Rehling, A. Alia, Abhishek Aich, Hauke B. Werner, Simone Schröder, Samy Hakroush, Eva Bartok, Katharina Ternka, Charlotte Schob, Julia Kitz, Susann Boretius, Dennis M. Krüger, Robert Epple, M. Sadman Sakib, Silvia Zampar, Gunther Hartmann, Matthias Kettwig, Lalit Kaurani, Stefan Nessler, Kristin Wendland, Oliver Wirths, Jutta Gärtner, Marco Prinz, Christine Stadelmann
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications 12(1), 6530 (2021). doi:10.1038/s41467-021-26880-x
Nature Communications, 12. Springer Science and Business Media LLC
Nature Communications
Nature Communications 12(1), 6530 (2021). doi:10.1038/s41467-021-26880-x
Nature Communications, 12. Springer Science and Business Media LLC
Nature Communications
Infantile-onset RNaseT2 deficient leukoencephalopathy is characterised by cystic brain lesions, multifocal white matter alterations, cerebral atrophy, and severe psychomotor impairment. The phenotype is similar to congenital cytomegalovirus brain inf
Autor:
Buerkner, Jonas Franz
The purpose of this study is to investigate the impacts of future social self-concepts on newcomer short-term adjustment. Employing a qualitative longitudinal design based on interviews, this work aims to uncover how the shape of identities before an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59c8818a690b9f0c6af79c8f9a216576