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pro vyhledávání: '"Jonas F Hummel"'
Eomes cannot replace its paralog T-bet during expansion and differentiation of CD8 effector T cells.
Autor:
Jonas Fixemer, Jonas F Hummel, Frederic Arnold, Christoph S N Klose, Alexis Hofherr, Kristoffer Weissert, Tamara Kögl, Michael Köttgen, Sebastian J Arnold, Peter Aichele, Yakup Tanriver
Publikováno v:
PLoS Pathogens, Vol 16, Iss 9, p e1008870 (2020)
The two T-box transcription factors T-bet and Eomesodermin (Eomes) are important regulators of cytotoxic lymphocytes (CTLs), such as activated CD8 T cells, which are essential in the fight against intracellular pathogens and tumors. Both transcriptio
Externí odkaz:
https://doaj.org/article/59bf0be84e5b40e89dd6faa33ec58339
Autor:
Benedikt Thelen, Vincent Schipperges, Paulina Knörlein, Jonas F. Hummel, Frederic Arnold, Laurence Kupferschmid, Christoph S. N. Klose, Sebastian J. Arnold, Melanie Boerries, Yakup Tanriver
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The T-box transcription factors T-bet and Eomesodermin regulate type 1 immune responses in innate and adaptive lymphocytes. T-bet is widely expressed in the immune system but was initially identified as the lineage-specifying transcription factor of
Externí odkaz:
https://doaj.org/article/4c5f1626cfc8418480d9a58bd7d61b97
Autor:
Dominic Grün, Christian Schachtrup, Yakup Tanriver, Karolina Ebert, Philip Konrad, Sebastian J. Arnold, Jonas Fixemer, Patrice Zeis, Jonas F. Hummel
Publikováno v:
Mucosal Immunology. 13:257-270
Natural intraepithelial lymphocytes (IELs) are thymus-derived adaptive immune cells, which are important contributors to intestinal immune homeostasis. Similar to other innate-like T cells, they are induced in the thymus through high-avidity interact
Autor:
Laurenz A. Herr, Gina J. Fiala, Anna-Maria Schaffer, Katrin Raute, Rubí M.-H. Velasco Cárdenas, Jonas F. Hummel, Karolina Ebert, Yakup Tanriver, Susana Minguet, Wolfgang W. Schamel
Publikováno v:
SSRN Electronic Journal.
The stepwise development of thymic invariant natural killer T (iNKT) cells is controlled by the TCR signal strength. The scaffold protein Kinase D interacting substrate of 220 kDa (Kidins220) binds to the TCR regulating TCR signaling. T cell-specific
Autor:
Christoph S. N. Klose, Tamara Kögl, Michael Köttgen, Jonas Fixemer, Sebastian J. Arnold, Frederic Arnold, Kristoffer Weissert, Alexis Hofherr, Yakup Tanriver, Peter Aichele, Jonas F. Hummel
Publikováno v:
PLoS Pathogens, Vol 16, Iss 9, p e1008870 (2020)
PLoS Pathogens
PLOS Pathogens
PLoS Pathogens
PLOS Pathogens
The two T-box transcription factors T-bet and Eomesodermin (Eomes) are important regulators of cytotoxic lymphocytes (CTLs), such as activated CD8 T cells, which are essential in the fight against intracellular pathogens and tumors. Both transcriptio
Autor:
Yannick d’Hargues, Jonas F. Hummel, Christoph S.N. Klose, Lena Faller, Yakup Tanriver, Karolina Ebert
Publikováno v:
Mucosal Immunology. 11:333-344
The intestine is a major immune organ with several specialized lymphoid structures and immune cells. Among these are thymus-derived natural intraepithelial lymphocytes (IELs) that lack expression of the classical co-receptors CD4 or CD8αβ (double n
Autor:
Jonas F, Hummel, Patrice, Zeis, Karolina, Ebert, Jonas, Fixemer, Philip, Konrad, Christian, Schachtrup, Sebastian J, Arnold, Dominic, Grün, Yakup, Tanriver
Publikováno v:
Mucosal Immunology
Natural intraepithelial lymphocytes (IELs) are thymus-derived adaptive immune cells, which are important contributors to intestinal immune homeostasis. Similar to other innate-like T cells, they are induced in the thymus through high-avidity interact
Autor:
Simone, Probst, Ray A, Daza, Natalie, Bader, Jonas F, Hummel, Matthias, Weiß, Yakup, Tanriver, Robert F, Hevner, Sebastian J, Arnold
Publikováno v:
Genesis (New York, N.Y. : 2000). 55(8)
The T-box transcription factor Eomes (also known as Tbr2) shows short-lived expression in various localized domains of the embryo, including epiblast cells during gastrulation and intermediate progenitor cells in the cerebral cortex. In these tissues
Autor:
Christoph S N, Klose, Jonas F, Hummel, Lena, Faller, Yannick, d'Hargues, Karolina, Ebert, Yakup, Tanriver
Publikováno v:
Mucosal immunology. 11(2)
The intestine is a major immune organ with several specialized lymphoid structures and immune cells. Among these are thymus-derived natural intraepithelial lymphocytes (IELs) that lack expression of the classical co-receptors CD4 or CD8αβ (double n