Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jonas Ellegaard Nielsen"'
Autor:
Jonas Ellegaard Nielsen, Bent Honoré, Karsten Vestergård, Raluca Georgiana Maltesen, Gunna Christiansen, Anna Uhd Bøge, Søren Risom Kristensen, Shona Pedersen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Alzheimer’s disease (AD) is the most common form of dementia and without readily available clinical biomarkers. Blood-derived proteins are routinely used for diagnostics; however, comprehensive plasma profiling is challenging due to the dy
Externí odkaz:
https://doaj.org/article/41fc1d200018460e9fa27e434581d2aa
Autor:
Mads Odgaard Mæng, Nirrooja Roshanth, Anders Kruse, Jonas Ellegaard Nielsen, Benedict Kjærgaard, Bent Honoré, Henrik Vorum, Lasse Jørgensen Cehofski
Publikováno v:
Medicina, Vol 59, Iss 2, p 243 (2023)
Retinal vein occlusion (RVO) is a frequent visually disabling condition. The management of RVO continues to challenge clinicians. Macular edema secondary to RVO is often recurrent, and patients typically require intravitreal injections for several ye
Externí odkaz:
https://doaj.org/article/4fd0aa17351b4ad9b90325a98e5c7dd0
Autor:
Jonas Ellegaard Nielsen, Raluca Georgiana Maltesen, Jesper F. Havelund, Nils J. Færgeman, Charlotte Held Gotfredsen, Karsten Vestergård, Søren Risom Kristensen, Shona Pedersen
Publikováno v:
Metabolism Open, Vol 12, Iss , Pp 100125- (2021)
Background: Alzheimer's Disease (AD) is a complex and multifactorial disease and novel approaches are needed to illuminate the underlying pathology. Metabolites comprise the end-product of genes, transcripts, and protein regulations and might reflect
Externí odkaz:
https://doaj.org/article/ecfb0607ea694f328606f3b4d43b10a6
Autor:
Lasse Jørgensen Cehofski, Anders Kruse, Alexander Nørgård Alsing, Benn Falch Sejergaard, Jonas Ellegaard Nielsen, Shona Pedersen, Danson Vasanthan Muttuvelu, Svend Kirkeby, Bent Honoré, Henrik Vorum
Publikováno v:
Journal of Ophthalmology, Vol 2021 (2021)
Aflibercept is an inhibitor of vascular endothelial growth factor (VEGF) used to treat macular edema following branch retinal vein occlusion (BRVO). Despite well-documented efficacy, there is limited knowledge about proteome changes following afliber
Externí odkaz:
https://doaj.org/article/7ed43e36925d438e9ec9f181dab37c1f
Autor:
Lasse Jørgensen Cehofski, Anders Kruse, Alexander Nørgaard Alsing, Benn Falch Sejergaard, Jonas Ellegaard Nielsen, Anders Schlosser, Grith Lykke Sorensen, Jakob Grauslund, Bent Honoré, Henrik Vorum
Publikováno v:
Molecules, Vol 27, Iss 11, p 3360 (2022)
Aflibercept is a frequently used inhibitor of vascular endothelial growth factor (VEGF) in the treatment of macular edema following central retinal vein occlusion (CRVO). Retinal proteome changes following aflibercept intervention in CRVO remain larg
Externí odkaz:
https://doaj.org/article/dec14c5c575d43af9890fd2508396538
Autor:
Jonas Ellegaard Nielsen, Kamilla Sofie Pedersen, Karsten Vestergård, Raluca Georgiana Maltesen, Gunna Christiansen, Søren Lundbye-Christensen, Torben Moos, Søren Risom Kristensen, Shona Pedersen
Publikováno v:
Biomedicines, Vol 8, Iss 7, p 199 (2020)
Easily accessible biomarkers for Alzheimer’s dementia (AD) are lacking and established clinical markers are limited in applicability. Blood is a common biofluid for biomarker discoveries, and extracellular vesicles (EVs) may provide a matrix for ex
Externí odkaz:
https://doaj.org/article/e7e406c5e44d43909bb9aa181824e040
Autor:
Jonas Ellegaard Nielsen, Trygve Andreassen, Charlotte Held Gotfredsen, Dorte Aalund Olsen, Karsten Vestergaard, Jonna Skov Madsen, Søren Risom Kristensen, Shona Pedersen
Background: Alzheimer’s Disease (AD) is complex and novel approaches are urgently needed to characterise disease pathology and to aid in diagnosis. Metabolites are the end-products of upstream molecular alterations, whereby small changes at the gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c6b856f1b934533370fc95434ea8043
https://doi.org/10.21203/rs.3.rs-2765583/v1
https://doi.org/10.21203/rs.3.rs-2765583/v1
Autor:
Nanna Vestergaard, Lasse Jørgensen Cehofski, Alexander Nørgård Alsing, Anders Kruse, Jonas Ellegaard Nielsen, Anders Schlosser, Grith Lykke Sorensen, Bent Honoré, Henrik Vorum
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 7919
Vestergaard, N, Cehofski, L J, Alsing, A N, Kruse, A, Nielsen, J E, Schlosser, A, Sorensen, G L, Honoré, B & Vorum, H 2023, ' Large-Scale Protein Analysis of Experimental Retinal Artery Occlusion ', International Journal of Molecular Sciences, vol. 24, no. 9, 7919 . https://doi.org/10.3390/ijms24097919
Vestergaard, N, Cehofski, L J, Alsing, A N, Kruse, A, Nielsen, J E, Schlosser, A, Sorensen, G L, Honoré, B & Vorum, H 2023, ' Large-Scale Protein Analysis of Experimental Retinal Artery Occlusion ', International Journal of Molecular Sciences, vol. 24, no. 9 . https://doi.org/10.3390/ijms24097919
Vestergaard, N, Cehofski, L J, Alsing, A N, Kruse, A, Nielsen, J E, Schlosser, A, Sorensen, G L, Honoré, B & Vorum, H 2023, ' Large-Scale Protein Analysis of Experimental Retinal Artery Occlusion ', International Journal of Molecular Sciences, vol. 24, no. 9, 7919 . https://doi.org/10.3390/ijms24097919
Vestergaard, N, Cehofski, L J, Alsing, A N, Kruse, A, Nielsen, J E, Schlosser, A, Sorensen, G L, Honoré, B & Vorum, H 2023, ' Large-Scale Protein Analysis of Experimental Retinal Artery Occlusion ', International Journal of Molecular Sciences, vol. 24, no. 9 . https://doi.org/10.3390/ijms24097919
Retinal artery occlusion (RAO) is a devastating condition with no effective treatment. The management of RAO could potentially be improved through an in-depth understanding of the molecular alterations in the condition. This study combined advanced p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e0952f99bb1cfba5c8da95e885ef8d
https://doi.org/10.3390/ijms24097919
https://doi.org/10.3390/ijms24097919
Autor:
Karsten Vestergård, Jesper F. Havelund, Nils J. Færgeman, Shona Pedersen, Charlotte Held Gotfredsen, Raluca Maltesen, Søren Risom Kristensen, Jonas Ellegaard Nielsen
Publikováno v:
Metabolism Open, Vol 12, Iss, Pp 100125-(2021)
Nielsen, J E, Maltesen, R G, Havelund, J F, Færgeman, N J, Gotfredsen, C H, Vestergård, K, Kristensen, S R & Pedersen, S 2021, ' Characterising Alzheimer's disease through integrative NMR-and LC-MS-based metabolomics ', Metabolism Open, vol. 12, 100125 . https://doi.org/10.1016/j.metop.2021.100125
Nielsen, J E, Maltesen, R G, Havelund, J F, Færgeman, N J, Gotfredsen, C H, Vestergård, K, Kristensen, S R & Pedersen, S 2021, ' Characterising Alzheimer's disease through integrative NMR-and LC-MS-based metabolomics ', Metabolism open, vol. 12, 100125 . https://doi.org/10.1016/j.metop.2021.100125
Metabolism Open
Nielsen, J E, Maltesen, R G, Havelund, J F, Færgeman, N J, Gotfredsen, C H, Vestergård, K, Kristensen, S R & Pedersen, S 2021, ' Characterising Alzheimer's disease through integrative NMR-and LC-MS-based metabolomics ', Metabolism Open, vol. 12, 100125 . https://doi.org/10.1016/j.metop.2021.100125
Nielsen, J E, Maltesen, R G, Havelund, J F, Færgeman, N J, Gotfredsen, C H, Vestergård, K, Kristensen, S R & Pedersen, S 2021, ' Characterising Alzheimer's disease through integrative NMR-and LC-MS-based metabolomics ', Metabolism open, vol. 12, 100125 . https://doi.org/10.1016/j.metop.2021.100125
Metabolism Open
Background: Alzheimer's Disease (AD) is a complex and multifactorial disease and novel approaches are needed to illuminate the underlying pathology. Metabolites comprise the end-product of genes, transcripts, and protein regulations and might reflect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36710fd7cf80b8c201090924500ca109
http://www.sciencedirect.com/science/article/pii/S2589936821000499
http://www.sciencedirect.com/science/article/pii/S2589936821000499