Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jonas Doerr"'
Autor:
Kate Senger, Wenlin Yuan, Meredith Sagolla, Jonas Doerr, Brad Bolon, James Ziai, Kai‐Hui Sun, Soren Warming, Merone Roose‐Girma, Na Zhang, Lucinda Tam, Robert J. Newman, Subhra Chaudhuri, Aju Antony, Leonard D. Goldstein, Steffen Durinck, Bijay S. Jaiswal, Daniel Lafkas, Zora Modrusan, Somasekar Seshagiri
Publikováno v:
Advanced Genetics, Vol 2, Iss 1, Pp n/a-n/a (2021)
Abstract ERBB3 is a pseudokinase domain‐containing member of the ERBB family of receptor tyrosine kinases (RTKs). Following ligand binding, ERBB receptors homo‐ or hetero‐dimerize, leading to a head‐to‐tail arrangement of the intracellular
Externí odkaz:
https://doaj.org/article/e07cd0add97d47c6835d733394de07a7
Autor:
Jonas Doerr, Martin Karl Schwarz, Dirk Wiedermann, Anke Leinhaas, Alina Jakobs, Florian Schloen, Inna Schwarz, Michael Diedenhofen, Nils Christian Braun, Philipp Koch, Daniel A. Peterson, Ulrich Kubitscheck, Mathias Hoehn, Oliver Brüstle
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
Transplantation of cells into the central nervous system has developed into a major avenue for replacing neurons lost to neurodegenerative disease. Here the authors develop an approach combining viral-based transynaptic tracing labeling and whole bra
Externí odkaz:
https://doaj.org/article/2cbee1c0f4eb4c74965a509ea89d4813
Autor:
Guadalupe Ortiz-Muñoz, Markus Brown, Catherine B. Carbone, Ximo Pechuan-Jorge, Vincent Rouilly, Henrik Lindberg, Alex T. Ritter, Gautham Raghupathi, Qianbo Sun, Tess Nicotra, Shreya R. Mantri, Angela Yang, Jonas Doerr, Deepti Nagarkar, Spyros Darmanis, Benjamin Haley, Sanjeev Mariathasan, Yulei Wang, Carlos Gomez-Roca, Carlos Eduardo de Andrea, David Spigel, Thomas Wu, Lelia Delamarre, Johannes Schöneberg, Zora Modrusan, Richard Price, Shannon J. Turley, Ira Mellman, Christine Moussion
Publikováno v:
Nature.
The immune phenotype of a tumour is a key predictor of its response to immunotherapy1–4. Patients who respond to checkpoint blockade generally present with immune-inflamed5–7 tumours that are highly infiltrated by T cells. However, not all inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8538c3f5c22f9717c1cbbb9f3b2027c
https://doi.org/10.1038/s41586-023-06132-2
https://doi.org/10.1038/s41586-023-06132-2
Autor:
Alessandra Castiglioni, Markus Brown, Jillian L. Astarita, Mark Z. Chen, Lucinda Tam, Richard Bourgon, Claudia X. Dominguez, Shilpa Keerthivasan, Cecile Chalouni, Wendy Sandoval, Viviana Cremasco, Xiumin Wu, Yeqing Angela Yang, Andrey S. Shaw, Frederic J. de Sauvage, Ira Mellman, Elaine E. Storm, Catherine B Carbone, Merone Roose-Girma, Zora Modrusan, Amber W. Wang, Akshay T. Krishnamurty, Yasin Senbabaoglu, Wyne P. Lee, Jonas Doerr, Maximilian Nitschké, Shannon J. Turley, Varun N. Kapoor, Ryan Lane, Sören Müller, Christine Moussion
Publikováno v:
Nature Immunology. 22:571-585
Fibroblastic reticular cells (FRCs) are specialized stromal cells that define tissue architecture and regulate lymphocyte compartmentalization, homeostasis, and innate and adaptive immunity in secondary lymphoid organs (SLOs). In the present study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2383e3a737dd8c2478d0ddc2038bf224
https://doi.org/10.1038/s41590-021-00920-6
https://doi.org/10.1038/s41590-021-00920-6
Autor:
Yang A, Alex T. Ritter, Christine Moussion, de Andrea Ce, Zora Modrusan, Shannon J. Turley, Spigel D, Yulei Wang, Markus Brown, Price R, Thomas D. Wu, Darya Y. Orlova, Pechuan-Jorge J, Ira Mellman, Ortiz-Muñoz G, Gomez-Roca C, Sanjeev Mariathasan, Catherine B Carbone, Jonas Doerr, Mantri
SummaryThe immune phenotype of a tumor is a key predictor of its response to immunotherapy1–4. Patients who respond to immune checkpoint blockade generally present with tumors that are infiltrated by activated T cells, a tumor-immune phenotype refe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9a3ef624416623587babbf1a616223e
https://doi.org/10.1101/2021.05.27.445482
https://doi.org/10.1101/2021.05.27.445482
Autor:
Jun Chen, Justin Elstrott, Lan Wang, Simon S. Gao, Richard A.D. Carano, Jose E. Heredia, Elisia Villemure, Daniel G. Shore, Wyne P. Lee, Bobby Brillantes, Joseph H. Lin, Liling Liu, David H. Hackos, Jens Kortmann, Matthew Volgraf, Daniel D. Bravo, Christine Tam, Lorena Riol-Blanco, Steven Magnuson, Lionel Rouge, Chris Bjornson, Baihua Hu, Tania Chernov-Rogan, Rebecca M. Reese, Christopher P. Arthur, Min Jung, Michelle Dourado, Xiumin Wu, Victory Joseph, Alberto Estevez, John Liu, Alvin Gogineni, Juan Zhang, Laurie Leong, Jian Payandeh, Vishal Verma, Shannon D. Shields, Han Ting Ding, Brian Safina, Alessia Balestrini, Yong Chen, Vineela D. Gandham, Eric Suto, Jianyong Wang, Justin Ly, Rebecca N. Bauer, Jonas Doerr, Alexis Rohou, Cary D. Austin, Jason A. Vander Heiden, Xiaoying Yang, Ryan L. Wong, Lucinda Tam, Liuxi Chen, Kathy Hötzel, Kai H. Barck, Merone Roose-Girma, Claudio Ciferri, Huifen Chen, Bianca M. Liederer
Publikováno v:
Journal of Experimental Medicine. 218
Despite the development of effective therapies, a substantial proportion of asthmatics continue to have uncontrolled symptoms, airflow limitation, and exacerbations. Transient receptor potential cation channel member A1 (TRPA1) agonists are elevated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7586a7b163f0274f73ff2d6634f422f1
https://doi.org/10.1084/jem.20201637
https://doi.org/10.1084/jem.20201637
Autor:
Kate Senger, Merone Roose-Girma, Jonas Doerr, Meredith Sagolla, Robert J. Newman, Wenlin Yuan, Subhra Chaudhuri, Aju Antony, Lucinda Tam, Somasekar Seshagiri, Bijay S. Jaiswal, Leonard D. Goldstein, Søren Warming, Zora Modrusan, Brad Bolon, James Ziai, Na Zhang, Kai-Hui Sun, Steffen Durinck, Daniel Lafkas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f4f69356ef701357af12a52997bc696
https://doi.org/10.1002/ggn2.10036/v2/response1
https://doi.org/10.1002/ggn2.10036/v2/response1
Autor:
Philipp Koch, Christa E. Müller, Julius A. Steinbeck, Ruven Wilkens, Philip D. Gregory, Daniel Poppe, Marion Schneider, Julia Ladewig, Andreas Reik, David Paschon, Allison Tam, Jonas Doerr, Oliver Brüstle
Publikováno v:
Stem Cells Translational Medicine
As a powerful regulator of cellular homeostasis and metabolism, adenosine is involved in diverse neurological processes including pain, cognition, and memory. Altered adenosine homeostasis has also been associated with several diseases such as depres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c9130ac32fa7926737d8d4cf68800fa
https://doi.org/10.1002/sctm.16-0272
https://doi.org/10.1002/sctm.16-0272
Autor:
Anna-Maria Herzner, Tommy K. Cheung, Yogesh Goyal, Xiaotian Zhang, Jonas Doerr, David Arnott, Subhra Chaudhuri, Colin K. Watanabe, Trinna L. Cuellar, Steffen Durinck, Benjamin Haley, Jeremy Stinson, Brad A. Friedman, Zora Modrusan, Vasantharajan Janakiraman, Marie Classon
Publikováno v:
Journal of Cell Biology. 216:3535-3549
A propensity for rewiring genetic and epigenetic regulatory networks, thus enabling sustained cell proliferation, suppression of apoptosis, and the ability to evade the immune system, is vital to cancer cell propagation. An increased understanding of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44f0b570d560bbe714a11dfc2e089091
https://doi.org/10.1083/jcb.201612160
https://doi.org/10.1083/jcb.201612160
Autor:
Varun N, Kapoor, Sören, Müller, Shilpa, Keerthivasan, Markus, Brown, Cecile, Chalouni, Elaine E, Storm, Alessandra, Castiglioni, Ryan, Lane, Maximilian, Nitschke, Claudia X, Dominguez, Jillian L, Astarita, Akshay T, Krishnamurty, Catherine B, Carbone, Yasin, Senbabaoglu, Amber W, Wang, Xiumin, Wu, Viviana, Cremasco, Merone, Roose-Girma, Lucinda, Tam, Jonas, Doerr, Mark Z, Chen, Wyne P, Lee, Zora, Modrusan, Yeqing Angela, Yang, Richard, Bourgon, Wendy, Sandoval, Andrey S, Shaw, Frederic J, de Sauvage, Ira, Mellman, Christine, Moussion, Shannon J, Turley
Publikováno v:
Nature immunology. 22(5)
Fibroblastic reticular cells (FRCs) are specialized stromal cells that define tissue architecture and regulate lymphocyte compartmentalization, homeostasis, and innate and adaptive immunity in secondary lymphoid organs (SLOs). In the present study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c34433813cfb4eea728ece92310aea55
https://pubmed.ncbi.nlm.nih.gov/34088748
https://pubmed.ncbi.nlm.nih.gov/34088748