Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jonas Carlsson Almlöf"'
Autor:
Jonas Carlsson Almlöf, Andrei Alexsson, Juliana Imgenberg-Kreuz, Lina Sylwan, Christofer Bäcklin, Dag Leonard, Gunnel Nordmark, Karolina Tandre, Maija-Leena Eloranta, Leonid Padyukov, Christine Bengtsson, Andreas Jönsen, Solbritt Rantapää Dahlqvist, Christopher Sjöwall, Anders A. Bengtsson, Iva Gunnarsson, Elisabet Svenungsson, Lars Rönnblom, Johanna K. Sandling, Ann-Christine Syvänen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Genome-wide association studies have identified risk loci for SLE, but a large proportion of the genetic contribution to SLE still remains unexplained. To detect novel risk genes, and to predict an individual’s SLE risk we designed a rando
Externí odkaz:
https://doaj.org/article/95b05eb647a546ff93ea49bf8605180e
Autor:
Carl D. Langefeld, Hannah C. Ainsworth, Deborah S. Cunninghame Graham, Jennifer A. Kelly, Mary E. Comeau, Miranda C. Marion, Timothy D. Howard, Paula S. Ramos, Jennifer A. Croker, David L. Morris, Johanna K. Sandling, Jonas Carlsson Almlöf, Eduardo M. Acevedo-Vásquez, Graciela S. Alarcón, Alejandra M. Babini, Vicente Baca, Anders A. Bengtsson, Guillermo A. Berbotto, Marc Bijl, Elizabeth E. Brown, Hermine I. Brunner, Mario H. Cardiel, Luis Catoggio, Ricard Cervera, Jorge M. Cucho-Venegas, Solbritt Rantapää Dahlqvist, Sandra D’Alfonso, Berta Martins Da Silva, Iñigo de la Rúa Figueroa, Andrea Doria, Jeffrey C. Edberg, Emőke Endreffy, Jorge A. Esquivel-Valerio, Paul R. Fortin, Barry I. Freedman, Johan Frostegård, Mercedes A. García, Ignacio García de la Torre, Gary S. Gilkeson, Dafna D. Gladman, Iva Gunnarsson, Joel M. Guthridge, Jennifer L. Huggins, Judith A. James, Cees G. M. Kallenberg, Diane L. Kamen, David R. Karp, Kenneth M. Kaufman, Leah C. Kottyan, László Kovács, Helle Laustrup, Bernard R. Lauwerys, Quan-Zhen Li, Marco A. Maradiaga-Ceceña, Javier Martín, Joseph M. McCune, David R. McWilliams, Joan T. Merrill, Pedro Miranda, José F. Moctezuma, Swapan K. Nath, Timothy B. Niewold, Lorena Orozco, Norberto Ortego-Centeno, Michelle Petri, Christian A. Pineau, Bernardo A. Pons-Estel, Janet Pope, Prithvi Raj, Rosalind Ramsey-Goldman, John D. Reveille, Laurie P. Russell, José M. Sabio, Carlos A. Aguilar-Salinas, Hugo R. Scherbarth, Raffaella Scorza, Michael F. Seldin, Christopher Sjöwall, Elisabet Svenungsson, Susan D. Thompson, Sergio M. A. Toloza, Lennart Truedsson, Teresa Tusié-Luna, Carlos Vasconcelos, Luis M. Vilá, Daniel J. Wallace, Michael H. Weisman, Joan E. Wither, Tushar Bhangale, Jorge R. Oksenberg, John D. Rioux, Peter K. Gregersen, Ann-Christine Syvänen, Lars Rönnblom, Lindsey A. Criswell, Chaim O. Jacob, Kathy L. Sivils, Betty P. Tsao, Laura E. Schanberg, Timothy W. Behrens, Earl D. Silverman, Marta E. Alarcón-Riquelme, Robert P. Kimberly, John B. Harley, Edward K. Wakeland, Robert R. Graham, Patrick M. Gaffney, Timothy J. Vyse
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Systemic lupus erythematosus (SLE) is an autoimmune disease with a strong ethnic and gender bias. In a transancestral genetic association study, Langefeldet al. identify 24 novel regions associated with risk to lupus and propose a cumulative hits hyp
Externí odkaz:
https://doaj.org/article/a68227bc3ba0457486591e4743061bf9
Autor:
Juliana Imgenberg-Kreuz, Jonas Carlsson Almlöf, Dag Leonard, Christopher Sjöwall, Ann-Christine Syvänen, Lars Rönnblom, Johanna K. Sandling, Gunnel Nordmark
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Objectives: To perform a cross-comparative analysis of DNA methylation in patients with systemic lupus erythematosus (SLE), patients with primary Sjögren's syndrome (pSS), and healthy controls addressing the question of epigenetic sharing and aiming
Externí odkaz:
https://doaj.org/article/24afcc9dfe7d414ea89a4956b54c3159
Autor:
Jonas Carlsson Almlöf, Per Lundmark, Anders Lundmark, Bing Ge, Tomi Pastinen, Cardiogenics Consortium, Alison H Goodall, François Cambien, Panos Deloukas, Willem H Ouwehand, Ann-Christine Syvänen
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102612 (2014)
We applied genome-wide allele-specific expression analysis of monocytes from 188 samples. Monocytes were purified from white blood cells of healthy blood donors to detect cis-acting genetic variation that regulates the expression of long non-coding R
Externí odkaz:
https://doaj.org/article/2e9d9228294a404dafb5b8b1a3ce4588
Autor:
Jonas Carlsson Almlöf, Per Lundmark, Anders Lundmark, Bing Ge, Seraya Maouche, Harald H H Göring, Ulrika Liljedahl, Camilla Enström, Jessy Brocheton, Carole Proust, Tiphaine Godefroy, Jennifer G Sambrook, Jennifer Jolley, Abigail Crisp-Hihn, Nicola Foad, Heather Lloyd-Jones, Jonathan Stephens, Rhian Gwilliam, Catherine M Rice, Christian Hengstenberg, Nilesh J Samani, Jeanette Erdmann, Heribert Schunkert, Tomi Pastinen, Panos Deloukas, Alison H Goodall, Willem H Ouwehand, François Cambien, Ann-Christine Syvänen
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52260 (2012)
A large number of genome-wide association studies have been performed during the past five years to identify associations between SNPs and human complex diseases and traits. The assignment of a functional role for the identified disease-associated SN
Externí odkaz:
https://doaj.org/article/d0a286581c23430fa9c2b3d1ada6f11f
Autor:
Gustav J. Ullenhag, Linnea La Fleur, Helena Nord, Gilbert Lauter, Dijana Cerjan, Max Backman, Hans Brunnström, Lotte Moens, Jonas Carlsson Almlöf, Hedvig Elfving, Erika Broström, Johan Botling, Carina Strell, Patrick Micke, Johanna Sofia Margareta Mattsson
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 151
Purpose The small molecule inhibitors larotrectinib and entrectinib have recently been approved as cancer agnostic drugs in patients with tumours harbouring a rearrangement of the neurotrophic tropomyosin receptor kinase (NTRK). These oncogenic fusio
Autor:
Iva Gunnarsson, Lars Rönnblom, Johanna K. Sandling, Giorgia Grosso, Anders A. Bengtsson, Maija-Leena Eloranta, Christopher Sjöwall, Jonas Carlsson Almlöf, Dag Leonard, Sara Nystedt, Elisabet Svenungsson, Andreas Jönsen, Ann-Christine Syvänen
Publikováno v:
Human Genetics
Systemic lupus erythematosus (SLE, OMIM 152700) is a systemic autoimmune disease with a complex etiology. The mode of inheritance of the genetic risk beyond familial SLE cases is currently unknown. Additionally, the contribution of heterozygous varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2278eddd9dbbdeeb60c3a35a4b135a6
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-154844
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-154844
Autor:
Ann-Christine Syvänen, Eva C. Berglund, Elin Övernäs, Jonas Abrahamsson, Jessica Nordlund, Anders Lundmark, Diana Ekman, Erik Forestier, Josefine Palle, Gudmar Lönnerholm, Amanda Raine, C. Mårten Lindqvist, Britt-Marie Frost, Eva Freyhult, Mats Heyman, Dan Grandér, Jonas Carlsson Almlöf
Publikováno v:
Oncotarget
To characterize the mutational patterns of acute lymphoblastic leukemia (ALL) we performed deep next generation sequencing of 872 cancer genes in 172 diagnostic and 24 relapse samples from 172 pediatric ALL patients. We found an overall greater mutat
Autor:
Roald Omdal, Katrine Brække Norheim, Ann-Christine Syvänen, Maija-Leena Eloranta, Linnea Signer, Jonas Carlsson Almlöf, Jessica Nordlund, Gunnel Nordmark, Lars Rönnblom, Juliana Imgenberg-Kreuz, Johanna K. Sandling
Publikováno v:
Annals of the Rheumatic Diseases
ObjectivesIncreasing evidence suggests an epigenetic contribution to the pathogenesis of autoimmune diseases, including primary Sjögren's Syndrome (pSS). The aim of this study was to investigate the role of DNA methylation in pSS by analysing multip
Autor:
Juliana, Imgenberg-Kreuz, Jonas, Carlsson Almlöf, Dag, Leonard, Andrei, Alexsson, Gunnel, Nordmark, Maija-Leena, Eloranta, Solbritt, Rantapää-Dahlqvist, Anders A, Bengtsson, Andreas, Jönsen, Leonid, Padyukov, Iva, Gunnarsson, Elisabet, Svenungsson, Christopher, Sjöwall, Lars, Rönnblom, Ann-Christine, Syvänen, Johanna K, Sandling
Publikováno v:
Annals of the Rheumatic Diseases
Objectives Systemic lupus erythematosus (SLE) is a chronic autoimmune condition with heterogeneous presentation and complex aetiology where DNA methylation changes are emerging as a contributing factor. In order to discover novel epigenetic associati