Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jonas Blaes"'
Autor:
Ana Victoria Ponce-Bobadilla, Sven Stodtmann, Mong-Jen Chen, Insa Winzenborg, Sven Mensing, Jonas Blaes, Tobias Haslberger, Loic Laplanche, Ingeborg Dreher, Nael M. Mostafa
Publikováno v:
Clinical Pharmacokinetics. 62:623-634
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf18a6e623ef2ba7b5c38294109c10bc
https://doi.org/10.1007/s40262-023-01221-x
https://doi.org/10.1007/s40262-023-01221-x
Autor:
Dieter Lemke, Wolfgang Wick, Harald Fricke, Michael Platten, Michael Kluge, Martin Bendszus, Claudia Kunz, Christian Gieffers, Jürgen Debus, Amir Abdollahi, Uwe Haberkorn, Manfred Jugold, Christian Merz, Benedikt Wiestler, Andreas von Deimling, Jaromir Sykora, Torsten Schmenger, Theresa Bunse, Antje Wick, Felix Sahm, Petra Rübmann, Philipp-Niclas Pfenning, Carina M. Thomé, Jonas Blaes
Supplementary Figure 1: Detection of asunercept/ APG101 in brains of treated mice. Supplementary Figure 2: qPCR for MMP2 (A) or MMP9 (B) and representative images of human microglia after 12 h treatment with vehicle (I), 20 µg/ml APG101 (II), 50 U/m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03dd0115f80e90f8b03640535eda7b58
https://doi.org/10.1158/1541-7786.22513288
https://doi.org/10.1158/1541-7786.22513288
Autor:
Frank Winkler, Wolfgang Wick, Heidi S. Phillips, Jeffrey J. Wallin, Laurent Salphati, Anna S. Berghoff, Miriam Gömmel, Gergely Solecki, Yunxiang Liao, Jonas Blaes, Matthias Osswald
Purpose: The role of blood–brain barrier (BBB) integrity for brain tumor biology and therapy is a matter of debate.Experimental Design: We developed a new experimental approach using in vivo two-photon imaging of mouse brain metastases originating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa9013f18f09085c031a94db5fe07ab6
https://doi.org/10.1158/1078-0432.c.6527139
https://doi.org/10.1158/1078-0432.c.6527139
Autor:
Frank Winkler, Wolfgang Wick, Heidi S. Phillips, Jeffrey J. Wallin, Laurent Salphati, Anna S. Berghoff, Miriam Gömmel, Gergely Solecki, Yunxiang Liao, Jonas Blaes, Matthias Osswald
A, Metastasis sizes in the different treatment groups at start of treatment (p=0.596, ANOVA on Ranks). B, Quantifications of the mean grey values of the sodium fluorescein signal, normalized to background signal. Note that all metastases could clearl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b6af80bb91ef3270129c76c98c2b52c
https://doi.org/10.1158/1078-0432.22469088
https://doi.org/10.1158/1078-0432.22469088
Autor:
Frank Winkler, Wolfgang Wick, Heidi S. Phillips, Jeffrey J. Wallin, Laurent Salphati, Anna S. Berghoff, Miriam Gömmel, Gergely Solecki, Yunxiang Liao, Jonas Blaes, Matthias Osswald
A, In permeable (red line) vs. non-permeable (green line) brain metastases, the extravasation of sodium fluorescein was significantly different directly after i.v. sodium fluorescein injection, and at the end of the corresponding time series (n=7 per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f95ea7e78febd5748ffc13a1ec49374
https://doi.org/10.1158/1078-0432.22469091.v1
https://doi.org/10.1158/1078-0432.22469091.v1
Autor:
Joanne Goodman, Jonas Blaes, John Cook, Kyra J. Cowan, Philip Timmerman, Joanna Grudzinska-Goebel, Madeleine Dahlbäck, Robert Nelson, Anna Laurén, Deborah McManus, Susanne Pihl
Publikováno v:
Bioanalysis. 13(7)
Immunogenicity assays are required to evaluate anti-drug antibody (ADA) responses that can be generated against biotherapeutic modalities. Regulatory guidelines focus on clinical requirements, yet it has become apparent that industry has applied thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd995f3a60ee4e75636d3730008c4faa
https://pubmed.ncbi.nlm.nih.gov/33729007
https://pubmed.ncbi.nlm.nih.gov/33729007
Autor:
Andreas von Deimling, Claudia Kunz, Philipp Niclas Pfenning, Antje Wick, Torsten Schmenger, Jürgen Debus, Martin Bendszus, Jonas Blaes, Dieter Lemke, Petra Rübmann, Christian Merz, Theresa Bunse, Harald Fricke, Felix Sahm, Michael Platten, Uwe Haberkorn, Michael Kluge, Wolfgang Wick, Christian Gieffers, Benedikt Wiestler, Jaromir Sykora, Manfred Jugold, Amir Abdollahi, Carina M. Thome
Publikováno v:
Molecular Cancer Research. 16:767-776
CD95 (Fas/APO-1), a death receptor family member, activity has been linked to tumorigenicity in multiple cancers, including glioblastoma multiforme (GBM). A phase II clinical trial on relapsed glioblastoma patients demonstrated that targeted inhibiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32cc54bef3714a9ad6bf52739f41148d
https://doi.org/10.1158/1541-7786.mcr-17-0563
https://doi.org/10.1158/1541-7786.mcr-17-0563
Autor:
Jonas Blaes, Miriam Gömmel, Jeffrey Wallin, Gergely Solecki, Wolfgang Wick, Yunxiang Liao, Laurent Salphati, Frank Winkler, Heidi S. Phillips, Matthias Osswald, Anna-Sophie Berghoff
Publikováno v:
Clinical Cancer Research. 22:6078-6087
Purpose: The role of blood–brain barrier (BBB) integrity for brain tumor biology and therapy is a matter of debate. Experimental Design: We developed a new experimental approach using in vivo two-photon imaging of mouse brain metastases originating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe9c7b129cc4eaaa0d9d697ae2b44b30
https://doi.org/10.1158/1078-0432.ccr-16-1327
https://doi.org/10.1158/1078-0432.ccr-16-1327
Autor:
Carina M. Thome, Marie Wüstner, Marcus Czabanka, Thomas Broggini, Ulrike Harms, Lena Stange, Jonas Blaes, Christoph Harms, Susanne Mueller, Peter Vajkoczy, Markus Weiler, Wolfgang Wick
Publikováno v:
Cancer Letters. 380:568-576
Hypoxia-regulated molecules play an important role in vascular resistance to antiangiogenic treatment. N-myc downstream-regulated-gene 1 (NDRG1) is significantly upregulated during hypoxia in glioma. It was the aim of the present study to analyze the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ec237412f38b9f5dbf7e821b2550ab
https://doi.org/10.1016/j.canlet.2015.06.026
https://doi.org/10.1016/j.canlet.2015.06.026
Autor:
Felix Sahm, Michael Platten, Frank Winkler, Martina Ott, Zhen Dong, Ann Catherine Steffen, Markus Weiler, Wolfgang Wick, Edward W. Green, Sarah Löw, Hans Werner Pledl, Jonas Blaes, Markus Zorn, Dieter Lemke, Anne Hertenstein, Manfred Jugold
Publikováno v:
Oncotarget
// Dieter Lemke 1, 2, 3 , Hans-Werner Pledl 1, 2, 3 , Markus Zorn 4 , Manfred Jugold 5 , Ed Green 1, 6 , Jonas Blaes 1, 2 , Sarah Low 1, 2, 3 , Anne Hertenstein 1, 2, 3 , Martina Ott 1, 6 , Felix Sahm 1, 7, 8 , Ann-Catherine Steffen 1, 2 , Markus Wei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e03dc49890433adef57f343ee5d5e9eb
https://doi.org/10.18632/oncotarget.10723
https://doi.org/10.18632/oncotarget.10723