Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Jonas, Ungerbäck"'
Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction
Autor:
Fatemeh Safi, Parashar Dhapola, Sarah Warsi, Mikael Sommarin, Eva Erlandsson, Jonas Ungerbäck, Rebecca Warfvinge, Ewa Sitnicka, David Bryder, Charlotta Böiers, Ram Krishna Thakur, Göran Karlsson
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113357- (2023)
Externí odkaz:
https://doaj.org/article/afa99b9a000946b79b1053681bd6ceed
Autor:
Christina T. Jensen, Josefine Åhsberg, Johanna Tingvall-Gustafsson, Rajesh Somasundaram, Stefan Lang, Jonas Ungerbäck, Anna Porwit, Shamit Soneji, Mikael Sigvardsson
Publikováno v:
Haematologica, Vol 108, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/1824c25cb8e9403ba9943e8c2d767111
Autor:
Kazuki Okuyama, Tobias Strid, Jacob Kuruvilla, Rajesh Somasundaram, Susana Cristobal, Emma Smith, Mahadesh Prasad, Thoas Fioretos, Henrik Lilljebjörn, Shamit Soneji, Stefan Lang, Jonas Ungerbäck, Mikael Sigvardsson
Publikováno v:
PLoS Genetics, Vol 15, Iss 8, p e1008280 (2019)
One of the most frequently mutated proteins in human B-lineage leukemia is the transcription factor PAX5. These mutations often result in partial rather than complete loss of function of the transcription factor. While the functional dose of PAX5 has
Externí odkaz:
https://doaj.org/article/5fcac02b5c7e4662a7aaef4e9b59c486
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
PU.1 is an ETS-family transcription factor that plays a broad range of roles in hematopoiesis. A direct regulator of myeloid, dendritic-cell, and B cell functional programs, and a well-known antagonist of terminal erythroid cell differentiation, it i
Externí odkaz:
https://doaj.org/article/04251b20a5ed4d7bb8cd693505b59513
Autor:
Christina T Jensen, Josefine Åhsberg, Johanna Tingvall-Gustafsson, Rajesh Somasundaram, Stefan Lang, Jonas Ungerbäck, Anna Porwit, Shamit Soneji, Mikael Sigvardsson
Publikováno v:
Haematologica.
Not available.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b05cb5bd1e75efe7caf244e8aba629d
https://doi.org/10.3324/haematol.2022.282430
https://doi.org/10.3324/haematol.2022.282430
Autor:
Trine A, Kristiansen, Qinyu, Zhang, Stefano, Vergani, Elena, Boldrin, Niklas, Krausse, Oscar, André, Pontus, Nordenfelt, Mikael, Sigvardsson, David, Bryder, Jonas, Ungerbäck, Joan, Yuan
Publikováno v:
Blood advances. 6(24)
The fetal-to-adult switch in hematopoietic stem cell (HSC) behavior is characterized by alterations in lineage output and entry into deep quiescence. Here we identify the emergence of megakaryocyte (Mk)-biased HSCs as an event coinciding with this de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d65db80b223c681c81cd3e17a606bf33
https://pubmed.ncbi.nlm.nih.gov/35584393
https://pubmed.ncbi.nlm.nih.gov/35584393
Autor:
Telma Lança, Jonas Ungerbäck, Clément Da Silva, Thorsten Joeris, Fatemeh Ahmadi, Julien Vandamme, Marcus Svensson-Frej, Allan McI Mowat, Knut Kotarsky, Mikael Sigvardsson, William W. Agace
Publikováno v:
Lança, T, Ungerbäck, J, Da Silva, C, Joeris, T, Ahmadi, F, Vandamme, J, Svensson-Frej, M, Mowat, A M I, Kotarsky, K, Sigvardsson, M & Agace, W W 2022, ' IRF8 deficiency induces the transcriptional, functional, and epigenetic reprogramming of cDC1 into the cDC2 lineage ', Immunity, vol. 55, no. 8, pp. 1431-1447.e11 . https://doi.org/10.1016/j.immuni.2022.06.006
Conventional dendritic cells (cDCs) consist of two major functionally and phenotypically distinct subsets, cDC1 and cDC2, whose development is dependent on distinct sets of transcription factors. Interferon regulatory factor 8 (IRF8) is required at m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aa86f4772b068f92f822991e8ba661f
https://orbit.dtu.dk/en/publications/63adde2f-e070-437d-82eb-7cb771ca08cd
https://orbit.dtu.dk/en/publications/63adde2f-e070-437d-82eb-7cb771ca08cd
Autor:
Mahadesh A J Prasad, Xun Wang, Mikael Sigvardsson, Kazuki Okuyama, Tobias Strid, Christina Jensen, James Hagman, Josefine Åhsberg, Rajesh Somasundaram, Shamit Soneji, Johanna Tingvall-Gustafsson, Jonas Ungerbäck
Publikováno v:
Blood
Genes encoding B lineage–restricted transcription factors are frequently mutated in B-lymphoid leukemias, suggesting a close link between normal and malignant B-cell development. One of these transcription factors is early B-cell factor 1 (EBF1), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eea76900ff4e9fb1545bf3fc324fd0e
https://europepmc.org/articles/PMC8176764/
https://europepmc.org/articles/PMC8176764/
3204 – NK CELL-DEFECTS OCCURRING ALREADY AT THE PRE-MDS STAGE IN NUP98-HOXD13 TRANSGENIC MOUSE MODEL
Autor:
Gladys Telliam Dushime, Ouyang Yuan, Olga Kotova, Maciej Ciesla, Henrik Lilljebjörn, Jonas Ungerbäck, Thoas Fioretos, Cristian Bellodi, David Bryder, Ewa Sitnicka
Publikováno v:
Experimental Hematology. 111:S146-S147
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::671d56ae531921534a616403aa4b2e52
https://doi.org/10.1016/j.exphem.2022.07.260
https://doi.org/10.1016/j.exphem.2022.07.260
Autor:
Christina Jensen, Johanna Tingvall-Gustafsson, Mikael Sigvardsson, Tobias Strid, Susana Cristobal, Jacob Kuruvilla, Jonas Ungerbäck, Rajesh Somasundaram, Kazuki Okuyama, Josefine Åhsberg, Mahadesh A J Prasad, Stefan Lang, Shamit Soneji
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 206(11)
B lymphocyte development is dependent on the interplay between the chromatin landscape and lineage-specific transcription factors. It has been suggested that B lineage commitment is associated with major changes in the nuclear chromatin environment,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f8092ada76abcb4c80ac036c7b070c
https://pubmed.ncbi.nlm.nih.gov/34021049
https://pubmed.ncbi.nlm.nih.gov/34021049