Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jonah Riddell"'
Autor:
Ru Chen, Lisa A Lai, Yumi Sullivan, Melissa Wong, Lei Wang, Jonah Riddell, Linda Jung, Venu G. Pillarisetty, Teresa A. Brentnall, Sheng Pan
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Pancreatic cancer is a lethal disease with poor prognosis. Gemcitabine has been the first line systemic treatment for pancreatic cancer. However, the rapid development of drug resistance has been a major hurdle in gemcitabine therapy leading
Externí odkaz:
https://doaj.org/article/4330feb75977443b89a09ae113dbd509
Autor:
Lisa A. Lai, Lei Wang, Jonah Riddell, Venu G. Pillarisetty, Linda Jung, Ru Chen, Teresa A. Brentnall, Yumi Sullivan, Melissa Wong, Sheng Pan
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports
Scientific Reports
Pancreatic cancer is a lethal disease with poor prognosis. Gemcitabine has been the first line systemic treatment for pancreatic cancer. However, the rapid development of drug resistance has been a major hurdle in gemcitabine therapy leading to unsat
Publikováno v:
Lasers in Surgery and Medicine. 44:60-68
Background and Objective Photodynamic therapy (PDT) is FDA-approved anti-cancer modality for elimination of early disease and palliation in advanced disease. PDT efficacy depends in part on elicitation of a tumor-specific immune response that is depe
Autor:
Wiam Bshara, Barbara A. Foster, Jonah Riddell, Michael T. Moser, Joseph A. Spernyak, Sandra O. Gollnick
Publikováno v:
Cancer Research. 71:1637-1646
In recent years a number of studies have implicated chronic inflammation in prostate carcinogenesis. However, mitigating factors of inflammation in the prostate are virtually unknown. Toll-like receptor 4 (TLR4) activity is associated with inflammati
Autor:
Clement Ip, Jonah Riddell, Jong Hoon Park, Weon-Sup Lee, Young-Mee Park, Debashis Ghosh, Kyoung-Soo Choi
Publikováno v:
Journal of Biological Chemistry. 282:22011-22022
Human peroxiredoxins 1 and 2, also known as Prx1 and Prx2, are more than 90% homologous in their amino acid sequences. Prx1 and Prx2 are elevated in various cancers and are shown to influence diverse cellular processes. Although their growth regulato
Autor:
Barbara A. Foster, Patricia Maier, Sandra O. Gollnick, Stephanie N. Sass, Jonah Riddell, Michael T. Moser
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50394 (2012)
PLoS ONE
PLoS ONE
Chronic inflammation leads to the formation of a pro-tumorigenic microenvironment that can promote tumor development, growth and differentiation through augmentation of tumor angiogenesis. Prostate cancer (CaP) risk and prognosis are adversely correl
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 184(2)
Peroxiredoxin 1 (Prx1) is an antioxidant and molecular chaperone that can be secreted from tumor cells. Prx1 is overexpressed in many cancers, and elevation of Prx1 is associated with poor clinical outcome. In the current study, we demonstrate that i
Autor:
Weonsup, Lee, Kyoung-Soo, Choi, Jonah, Riddell, Clement, Ip, Debashis, Ghosh, Jong-Hoon, Park, Young-Mee, Park
Publikováno v:
The Journal of biological chemistry. 282(30)
Human peroxiredoxins 1 and 2, also known as Prx1 and Prx2, are more than 90% homologous in their amino acid sequences. Prx1 and Prx2 are elevated in various cancers and are shown to influence diverse cellular processes. Although their growth regulato
Publikováno v:
The Journal of Immunology. 184:101.34-101.34
Elevated Peroxiredoxin 1 (Prx1) expression is a poor prognostic factor in various cancers. Prx1 is an intracellular antioxidant and molecular chaperone protein that is non-classically secreted from transformed or stressed cells. Prx1 was found to inc
Autor:
Assieh Saadatpour, Stuart H. Orkin, Guoji Guo, Roi Gazit, Wataru Ebina, Brian S. Garrison, Jonah Riddell, Derrick J. Rossi, Pavel Volchkov, Guo-Cheng Yuan, Pankaj Mandal
Publikováno v:
Cell. (1):226
SummaryHematopoietic stem cells (HSCs) sustain blood formation throughout life and are the functional units of bone marrow transplantation. We show that transient expression of six transcription factors Run1t1, Hlf, Lmo2, Prdm5, Pbx1, and Zfp37 impar