Clinical features and management of human monkeypox: a retrospective observational study in the UK

Autor: Hugh Adler, Susan Gould, Paul Hine, Luke B Snell, Waison Wong, Catherine F Houlihan, Jane C Osborne, Tommy Rampling, Mike BJ Beadsworth, Christopher JA Duncan, Jake Dunning, Tom E Fletcher, Ewan R Hunter, Michael Jacobs, Saye H Khoo, William Newsholme, David Porter, Robert J Porter, Libuše Ratcliffe, Matthias L Schmid, Malcolm G Semple, Anne J Tunbridge, Tom Wingfield, Nicholas M Price, Mike Abouyannis, Asma Al-Balushi, Stephen Aston, Robert Ball, Nicholas J Beeching, Thomas J Blanchard, Ffion Carlin, Geraint Davies, Angela Gillespie, Scott R Hicks, Marie-Claire Hoyle, Chinenye Ilozue, Luke Mair, Suzanne Marshall, Anne Neary, Emmanuel Nsutebu, Samantha Parker, Hannah Ryan, Lance Turtle, Chris Smith, Jon van Aartsen, Naomi F Walker, Stephen Woolley, Anu Chawla, Ian Hart, Anna Smielewska, Elizabeth Joekes, Cathryn Benson, Cheryl Brindley, Urmi Das, Chin K Eyton-Chong, Claire Gnanalingham, Clare Halfhide, Beatriz Larru, Sarah Mayell, Joanna McBride, Claire Oliver, Princy Paul, Andrew Riordan, Lekha Sridhar, Megan Storey, Audrey Abdul, Jennifer Abrahamsen, Breda Athan, Sanjay Bhagani, Colin S Brown, Oliver Carpenter, Ian Cropley, Kerrie Frost, Susan Hopkins, Jessica Joyce, Lucy Lamb, Adrian Lyons, Tabitha Mahungu, Stephen Mepham, Edina Mukwaira, Alison Rodger, Caroline Taylor, Simon Warren, Alan Williams, Debbie Levitt, Denise Allen, Jill Dixon, Adam Evans, Pauline McNicholas, Brendan Payne, D Ashley Price, Uli Schwab, Allison Sykes, Yusri Taha, Margaret Ward, Marieke Emonts, Stephen Owens, Alina Botgros, Sam T Douthwaite, Anna Goodman, Akish Luintel, Eithne MacMahon, Gaia Nebbia, Geraldine O'Hara, Joseph Parsons, Ashwin Sen, Daniel Stevenson, Tadgh Sullivan, Usman Taj, Claire van Nipsen tot Pannerden, Helen Winslow, Ewa Zatyka, Ekene Alozie-Otuka, Csaba Beviz, Yusupha Ceesay, Latchmin Gargee, Morloh Kabia, Hannah Mitchell, Shona Perkins, Mingaile Sasson, Kamal Sehmbey, Federico Tabios, Neil Wigglesworth, Emma J Aarons, Tim Brooks, Matthew Dryden, Jenna Furneaux, Barry Gibney, Jennifer Small, Elizabeth Truelove, Clare E Warrell, Richard Firth, Gemma Hobson, Christopher Johnson, Alison Dewynter, Sebastian Nixon, Oliver Spence, Joachim J Bugert, Dennis E Hruby

Background Cases of human monkeypox are rarely seen outside of west and central Africa. There are few data regarding viral kinetics or the duration of viral shedding and no licensed treatments. Two oral drugs, brincidofovir and tecovirimat, have been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e287fd12f14777099c17c4a2cd3957
https://ora.ox.ac.uk/objects/uuid:b4702035-0ad4-4de0-a058-16fc519f15ab

Piperacillin/tazobactam resistance in a clinical isolate of Escherichia coli due to IS26-mediated amplification of blaTEM-1B

Autor: Paul Roberts, Issra Bulgasim, Alice J. Fraser, Alasdair T. M. Hubbard, Adam P. Roberts, Thomas Edwards, Caroline E Corless, Alex Howard, Emily R. Adams, Jenifer Mason, Christopher M. Parry, Jon van Aartsen

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
NATURE COMMUNICATIONS
Nature Communications

A phenotype of Escherichia coli and Klebsiella pneumoniae, resistant to piperacillin/tazobactam (TZP) but susceptible to carbapenems and 3rd generation cephalosporins, has emerged. The resistance mechanism associated with this phenotype has been iden

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d8da4b3253a13e2da6dc7d0f93c6522
https://doi.org/10.1038/s41467-020-18668-2

Within-patient evolution to piperacillin/tazobactam resistance in a clinical isolate ofEscherichia colidue to IS26-mediated amplification ofblaTEM-1B

Autor: Adam P. Roberts, Emily R. Adams, Paul Roberts, Jon van Aartsen, Alice J. Fraser, Alasdair T. M. Hubbard, Thomas Edwards, Christopher M. Parry, Jenifer Mason, Alex Howard, Caroline E Corless

A novel phenotype ofEscherichia coliand Klebsiella pneumoniae resistant to piperacillin/tazobactam (TZP), but susceptible to carbapenems and 3rdgeneration cephalosporins has recently emerged. The resistance mechanism of this phenotype has been identi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4497429b1fc2ab15ac9e67d1eb993af5
https://doi.org/10.1101/2020.02.28.969360

Epidemiological and Molecular Characterization of an Invasive Group A Streptococcus emm32.2 Outbreak

Autor: Anmol M. Kiran, Jenny Clarke, Jennifer E. Cornick, Neil French, Laura Bricio Moreno, Roberto Vivancos, Edward Bevan, Angela H. Nobbs, Maaike Alaearts, Jon van Aartsen, Howard F. Jenkinson, James Anson, Aras Kadiolgu, Mansoor Alsahag, Dean Everett

Publikováno v: Journal of Clinical Microbiology
Cornick, J E, Kiran, A M, Vivancos, R, Van Aartsen, J, Clarke, J, Bevan, E, Alsahag, M, Alaearts, M, Bricio Moreno, L, Jenkinson, H F, Nobbs, A H, Anson, J, Kadiolgu, A, French, N & Everett, D B 2017, ' Epidemiological and Molecular Characterization of an Invasive Group A Streptococcus32.2 Outbreak ', Journal of Clinical Microbiology, vol. 55, no. 6, pp. 1837-1846 . https://doi.org/10.1128/JCM.00191-17
Cornick, J E, Kiran, A M, Vivancos, R, Van Aartsen, J, Clarke, J, Bevan, E, Alsahag, M, Alaearts, M, Moreno, L B, Jenkinson, H F, Nobbs, A H, Anson, J, Kadiolgu, A, French, N & Everett, D B 2017, ' Epidemiological and Molecular Characterization of an Invasive Group A Streptococcus emm 32.2 Outbreak ', Journal of Clinical Microbiology, vol. 55, no. 6, pp. 1837-1846 . https://doi.org/10.1128/JCM.00191-17

An emm 32.2 invasive group A streptococcus (iGAS) outbreak occurred in Liverpool from January 2010 to September 2012. This genotype had not previously been identified in Liverpool, but was responsible for 32% (14/44) of all iGAS cases reported during

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbd150ee0ebd7daf47e51f637f39e1c4