Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jon Wasson"'
Publikováno v:
BioTechniques, Vol 32, Iss 5, Pp 1144-1152 (2002)
Single nucleotide polymorphism (SNP) association studies searching for differences in allele frequencies between cases and controls have been widely used for genetic analysis. Individual genotyping is prohibitively expensive in large sample sizes. Po
Externí odkaz:
https://doaj.org/article/142aaeb6a55c42f4836661d6f48dec3b
Autor:
Rosalind J Neuman, Jon Wasson, Gil Atzmon, Julio Wainstein, Yair Yerushalmi, Joseph Cohen, Nir Barzilai, Ilana Blech, Benjamin Glaser, M Alan Permutt
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9903 (2010)
Evidence has accumulated that multiple genetic and environmental factors play important roles in determining susceptibility to type 2 diabetes (T2D). Although variants from candidate genes have become prime targets for genetic analysis, few studies h
Externí odkaz:
https://doaj.org/article/84510053daea43179543b6cbb29dbe9a
Autor:
Stéphane Cauchi, David Meyre, Emmanuelle Durand, Christine Proença, Michel Marre, Samy Hadjadj, Hélène Choquet, Franck De Graeve, Stefan Gaget, Frederic Allegaert, Jérôme Delplanque, Marshall Alan Permutt, Jon Wasson, Ilana Blech, Guillaume Charpentier, Beverley Balkau, Anne-Claire Vergnaud, Sébastien Czernichow, Wolfgang Patsch, Mohamed Chikri, Benjamin Glaser, Robert Sladek, Philippe Froguel
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2031 (2008)
Recently, several Genome Wide Association (GWA) studies in populations of European descent have identified and validated novel single nucleotide polymorphisms (SNPs), highly associated with type 2 diabetes (T2D). Our aims were to validate these marke
Externí odkaz:
https://doaj.org/article/4e7c6b6f070f4a8cadb0fec1a1e23371
Autor:
Benjamin Glaser, Andrew T. Hattersley, Jing Hua Zhao, Mark I. McCarthy, Nicholas J. Wareham, Graham A. Hitman, Ranganath Venkatesh, Eleftheria Zeggini, Panagiotis Deloukas, Michael N. Weedon, Sarah E. Hunt, Eleanor Wheeler, M. Alan Permutt, Richard Sherva, Marcos Delgado, Pamela Whittaker, Jian'an Luan, Timothy M. Frayling, Rosalind J. Neuman, Jon Wasson, Inês Barroso, Mark Walker
Publikováno v:
Diabetes
OBJECTIVE—Single nucleotide polymorphisms (SNPs) in the P2 promoter region of HNF4A were originally shown to be associated with predisposition for type 2 diabetes in Finnish, Ashkenazi, and, more recently, Scandinavian populations, but they generat
Publikováno v:
BioTechniques. 32:1144-1152
Single nucleotide polymorphism (SNP) association studies searching for differences in allele frequencies between cases and controls have been widely used for genetic analysis. Individual genotyping is prohibitively expensive in large sample sizes. Po
Autor:
Arun Shankar, Anupam Kumar, Gopikakrishnan Gopalakrishnan, Sunitha Jothydev, M. A. Permutt, Jothydev Kesavadev, Jon Wasson
Publikováno v:
Diabetes technologytherapeutics. 13(7)
Wolfram syndrome (WS), or DIDMOAD (diabetes insipidus, diabetes mellitus, optic atrophy, and deafness), is a rare autosomal recessive neurodegenerative disorder with a median life expectancy of 30 years and occurs in one in 770,000 live births. To da
Autor:
Ilana Blech, Joseph Cohen, Benjamin Glaser, Gil Atzmon, Julio Wainstein, M. Alan Permutt, Rosalind J. Neuman, Jon Wasson, Yair Yerushalmi, Nir Barzilai
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 3, p e9903 (2010)
PLoS ONE, Vol 5, Iss 3, p e9903 (2010)
BACKGROUND Evidence has accumulated that multiple genetic and environmental factors play important roles in determining susceptibility to type 2 diabetes (T2D). Although variants from candidate genes have become prime targets for genetic analysis, fe
Detailed investigation of the role of common and low-frequency WFS1 variants in type 2 diabetes risk
Autor:
Paul W. Franks, Manjinder S. Sandhu, Alan Permutt, Allan Daly, Mark I. McCarthy, Nicholas J. Wareham, Eleanor Wheeler, Benjamin Glaser, Andrew T. Hattersley, Katherine A. Fawcett, Göran Hallmans, Andrew P. Morris, Inês Barroso, Olov Rolandsson, Jon Wasson, Sally L. Ricketts
Publikováno v:
Diabetes
OBJECTIVE Wolfram syndrome 1 (WFS1) single nucleotide polymorphisms (SNPs) are associated with risk of type 2 diabetes. In this study we aimed to refine this association and investigate the role of low-frequency WFS1 variants in type 2 diabetes risk.
Autor:
Guillaume Charpentier, Frédéric Allegaert, Samy Hadjadj, M. A. Permutt, Michel Marre, Jérôme Delplanque, Benjamin Glaser, Ilana Blech, Robert Sladek, David Meyre, Stefan Gaget, Mohamed Chikri, Christine Proença, Jon Wasson, Philippe Froguel, Sébastien Czernichow, Stéphane Cauchi, Anne-Claire Vergnaud, Wolfgang Patsch, Hélène Choquet, Emmanuelle Durand, Beverley Balkau, Franck De Graeve
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2031 (2008)
PLoS ONE
PLoS ONE
Background Recently, several Genome Wide Association (GWA) studies in populations of European descent have identified and validated novel single nucleotide polymorphisms (SNPs), highly associated with type 2 diabetes (T2D). Our aims were to validate
Autor:
D. C. Rao, Steven C. Hunt, Jon Wasson, Lingwei Sun, Timothy Schappe, Rosalind J. Neuman, Samuel Klein, Richard Sherva, Latisha Love-Gregory, M. Alan Permutt, Alessandro Doria, Nada A. Abumrad
Publikováno v:
Human molecular genetics. 17(11)
A region along chromosome 7q was recently linked to components of the metabolic syndrome (MetS) in several genome-wide linkage studies. Within this region, the CD36 gene, which encodes a membrane receptor for long-chain fatty acids and lipoproteins,