Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jon W. Weeks"'
Autor:
Inga V. Leus, Jon W. Weeks, Vincent Bonifay, Yue Shen, Liang Yang, Connor J. Cooper, Dinesh Nath, Adam S. Duerfeldt, Jeremy C. Smith, Jerry M. Parks, Valentin V. Rybenkov, Helen I. Zgurskaya
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Two membrane cell envelopes act as selective permeability barriers in Gram-negative bacteria, protecting cells against antibiotics and other small molecules. Significant efforts are being directed toward understanding how small molecules per
Externí odkaz:
https://doaj.org/article/c8beeb71c6274a14889057ff8ee519e0
Autor:
Inga V. Leus, Jon W. Weeks, Vincent Bonifay, Yue Shen, Liang Yang, Connor J. Cooper, Dinesh Nath, Adam S. Duerfeldt, Jeremy C. Smith, Jerry M. Parks, Valentin V. Rybenkov, Helen I. Zgurskaya
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/2f4f4b54ca034d91a0ffcca607143010
Autor:
Suvajyoti Guha, David Wolloscheck, Narges Abdali, Catherine Wentz, Nicole Gillette, Kelly A. Bauer, Jon W. Weeks
Publikováno v:
Frontiers in Water, Vol 4 (2022)
Aerosols inadvertently generated by the bubbling of contaminated water in heater cooler devices (HCDs) have been associated with hundreds of patient infections. These aerosols are typically generated by bubbling within the water tanks of HCDs that su
Externí odkaz:
https://doaj.org/article/c97f67b752ad4cc389e2c185be7041e4
Publikováno v:
Frontiers in Public Health, Vol 8 (2020)
Externí odkaz:
https://doaj.org/article/a3a3bd19189e4e6ea837471ca135d5a9
Autor:
Ganesh Krishnamoorthy, Inga V. Leus, Jon W. Weeks, David Wolloscheck, Valentin V. Rybenkov, Helen I. Zgurskaya
Publikováno v:
mBio, Vol 8, Iss 5 (2017)
ABSTRACT Gram-negative bacteria are notoriously resistant to antibiotics, but the extent of the resistance varies broadly between species. We report that in significant human pathogens Acinetobacter baumannii, Pseudomonas aeruginosa, and Burkholderia
Externí odkaz:
https://doaj.org/article/adc70a34bd7f4c4f8e081217787984d9
Publikováno v:
Frontiers in Microbiology, Vol 6 (2015)
Gram- negative bacteria utilize a diverse array of multidrug transporters to pump toxic compounds out of cells. Some transporters together with periplasmic membrane fusion proteins (MFPs) and outer membrane channels assemble trans-envelope complexes
Externí odkaz:
https://doaj.org/article/17fa1b3e9d034c77b2ef978daddbdb8a
Autor:
Lucien Fabre, Abigail T. Ntreh, Amira Yazidi, Inga V. Leus, Sudipta Bhattacharyya, Helen I. Zgurskaya, Jurgen Sygusch, Jon W. Weeks, Jakob Ruickoldt, Isabelle Rouiller
Publikováno v:
Structure
The structure of the TriABC inner membrane component of the triclosan/SDS-specific efflux pump from Pseudomonas aeruginosa was determined by cryoelectron microscopy to 4.5 A resolution. The complete structure of the inner membrane transporter TriC of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26dd9afdb27849fca1eacc2ff7c48251
https://europepmc.org/articles/PMC7935746/
https://europepmc.org/articles/PMC7935746/
Autor:
Inga V. Leus, Helen I. Zgurskaya, Jon W. Weeks, Vincent Bonifay, Lauren Smith, Sophie Richardson
Publikováno v:
Journal of bacteriology. 202(8)
Antibiotic-resistant Acinetobacter baumannii causes infections that are extremely difficult to treat. A significant role in these resistance profiles is attributed to multidrug efflux pumps, especially those belonging to the resistance-nodulation-cel
Autor:
Ganesh Krishnamoorthy, Cameron Croft, Valentin V. Rybenkov, Jon W. Weeks, David Wolloscheck, Helen I. Zgurskaya
Publikováno v:
Antimicrobial Agents and Chemotherapy. 60:7372-7381
In Gram-negative bacteria, a synergistic relationship between slow passive uptake of antibiotics across the outer membrane and active efflux transporters creates a permeability barrier, which efficiently reduces the effective concentrations of antibi
Autor:
Ganesh Krishnamoorthy, Zhen Zhang, Jon W. Weeks, Robert K. Ernst, Helen I. Zgurskaya, Herbert P. Schweizer, Courtney E. Chandler, Haotian Xue
Burkholderia comprises species that are significant biothreat agents and common contaminants of pharmaceutical production facilities. Their extreme antibiotic resistance affects all classes of antibiotics, including polycationic polymyxins and aminog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e58763ed201704d32d9273d46da32e9
https://europepmc.org/articles/PMC6761493/
https://europepmc.org/articles/PMC6761493/