Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jon W. Marsh"'
Autor:
Jon W. Marsh, K. De Swapan
Publikováno v:
Viral Genome Methods ISBN: 9781003420163
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::929d9e9cb3f4332a53acf190476932d4
https://doi.org/10.1201/9781003420163-7
https://doi.org/10.1201/9781003420163-7
HIV-1 Nef Mediates Pak Phosphorylation of Mek1 Serine298 and Elicits an Active Phospho-state of Pak2
Publikováno v:
Current HIV Research. 11:198-209
The HIV-1 Nef protein brings about increased T cell activity and viral titers through mechanisms that are poorly understood. Nef activity has been described as an enhancer, but not an inducer, of certain signaling pathways that lead to T cell activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d4886725cc98c99f36dcc32869ce6b1
https://doi.org/10.2174/1570162x113119990039
https://doi.org/10.2174/1570162x113119990039
Publikováno v:
Anesthesiology. 118:587-601
Background—Although in vitro studies have identified numerous possible targets, the molecules that mediate the in vivo effects of volatile anesthetics remain largely unknown. The mammalian ryanodine receptor (Ryr) is a known halothane target, and w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e18d68dd694a1852e31d05c7d7f50ca
https://doi.org/10.1097/aln.0b013e31827e52c6
https://doi.org/10.1097/aln.0b013e31827e52c6
Autor:
Xuehua Xu, Juan Liu, Dongyang Yu, Alyson Yoder, James N. Cooper, Jeremy Kelly, Liane Agulto, Paul J. Vorster, David A. Stephany, Li Dong, Subashini R. Iyer, Yuntao Wu, Weifeng Wang, Jon W. Marsh
Publikováno v:
Cell. 134(5):782-792
SummaryBinding of the HIV envelope to the chemokine coreceptors triggers membrane fusion and signal transduction. The fusion process has been well characterized, yet the role of coreceptor signaling remains elusive. Here, we describe a critical funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb6c1f293eae8f64a0ea35cf1f11463
Publikováno v:
Virology. 372(2):300-312
Retroviruses require integration of their RNA genomes for both stability and productive viral replication. In HIV infection of non-dividing, resting CD4 T cells, where integration is greatly impeded, the reverse transcribed HIV DNA has limited biolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c54fc8bc4eb5774c4254320a7e769f90
Publikováno v:
Current HIV Research. 5:394-402
Measuring virion infectivity is critical for studying and monitoring the process of HIV-1 infection. The easiest and the most common method utilizes reporter cell lines based on the HIV LTR promoter. The early HIV gene product Tat amplifies expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbbbb666aed92e2d972712368728f30c
https://doi.org/10.2174/157016207781024018
https://doi.org/10.2174/157016207781024018
Autor:
Yuntao Wu, Jon W. Marsh
Publikováno v:
Journal of Virology. 77:10376-10382
Replication of human immunodeficiency virus (HIV) involves obligatory sequential processes. Following viral entry and reverse transcription, the newly synthesized viral DNA integrates into the host chromatin. Integration is mandatory for viral produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9d25ae2076bc2fb7a6a1f9630193fe1
https://doi.org/10.1128/jvi.77.19.10376-10382.2003
https://doi.org/10.1128/jvi.77.19.10376-10382.2003
Autor:
Jon W. Marsh
Publikováno v:
Archives of Biochemistry and Biophysics. 365:192-198
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cc720da78cb74779de852b8b0cf2bf6
https://doi.org/10.1006/abbi.1999.1208
https://doi.org/10.1006/abbi.1999.1208
Autor:
Jon W. Marsh, Michael Nunn
Publikováno v:
Journal of Virology. 70:6157-6161
Although human immunodeficiency virus (HIV) Nef is essential for the induction of AIDS, its biochemical function has remained an enigma. In this study, HIV Nef protein is shown to associate with a serine-threonine kinase that recognizes histone H4 as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ddffb78e646474a8ead8f7b1b914fa
https://doi.org/10.1128/jvi.70.9.6157-6161.1996
https://doi.org/10.1128/jvi.70.9.6157-6161.1996
Autor:
Jon W. Marsh, S K De
Publikováno v:
Journal of Biological Chemistry. 269:6656-6660
The human immunodeficiency virus type 1 (HIV-1) Nef is a myristylated 27-kDa, cytoplasmic protein. It is attributed to have suppressive effects on LTR-based expression and T cell activation. Additionally, SIV nef has been shown to possess an essentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c7c8b7381280a60beb640783ae5fa61
https://doi.org/10.1016/s0021-9258(17)37424-0
https://doi.org/10.1016/s0021-9258(17)37424-0