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pro vyhledávání: '"Jon V. Salazar"'
Autor:
Cynthia Hong, Robert Walczak, Helena Dhamko, Michelle N. Bradley, Chaitra Marathe, Rima Boyadjian, Jon V. Salazar, Peter Tontonoz
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 3, Pp 531-539 (2011)
Ligand activation of liver X receptors (LXRs) has been shown to impact both lipid metabolism and inflammation. One complicating factor in studies utilizing synthetic LXR agonists is the potential for pharmacologic and receptor-independent effects. He
Externí odkaz:
https://doaj.org/article/4cf9666bee714852a9bce1f5a9efa4f0
Autor:
Ayaka, Ito, Cynthia, Hong, Kazuhiro, Oka, Jon V, Salazar, Cody, Diehl, Joseph L, Witztum, Mercedes, Diaz, Antonio, Castrillo, Steven J, Bensinger, Lawrence, Chan, Peter, Tontonoz
Publikováno v:
Immunity. 45(6)
Liver X receptors (LXRs) are regulators of cholesterol metabolism that also modulate immune responses. Inactivation of LXR α and β in mice leads to autoimmunity; however, how the regulation of cholesterol metabolism contributes to autoimmunity is u