Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jon Sutton"'
Autor:
Marcel J. de Groot, Karen Maubach, Neil Victor Harris, Kenneth Lyle Clark, Andrea Taylor, Peter Lockey, Christopher Higgs, Amanda J. Woodrooffe, R.A. Coleman, Richard Jon Davis, Jon Sutton, David E. Clark
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:2212-2221
In this Letter, we present the results of a hit-finding and lead optimization programme against the EP4 receptor (EP4R). In a short time period, we were able to discover five structurally diverse series of hit compounds using a combination of virtual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::457e6d595baed8f00fee9134fa175352
https://doi.org/10.1016/j.bmcl.2014.02.068
https://doi.org/10.1016/j.bmcl.2014.02.068
Autor:
Sajad Mohammed, George Hynd, Nicholas C. Ray, Hazel Hunt, Shahadat Ahmed, Steve Daly, Peter Lockey, Gerry Buckley, Robert Roe, Jon Sutton, Robin D. Clark, Christine Blasey, Joe Belanoff, Elizabeth O'connor
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:7376-7380
We report the optimization of a series of non-steroidal GR antagonists that led to the identification of compound 7. This compound is efficacious when dosed orally in an olanzapine-induced weight gain model in rats.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::541110052c7b57a2ea48db89fe09a186
https://doi.org/10.1016/j.bmcl.2012.10.074
https://doi.org/10.1016/j.bmcl.2012.10.074
Publikováno v:
Bulletin of the American College of Surgeons. 99(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bc58a2cde693d19b2b50056bb09066e7
https://pubmed.ncbi.nlm.nih.gov/24868840
https://pubmed.ncbi.nlm.nih.gov/24868840
Publikováno v:
Social Development. 8:117-127
Bullying in schools has been found to be widespread. The popular stereotype of a bully, supported by theories based on the social skills deficit model, is of a powerful but ‘oafish’ person with little understanding of others. In this article, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c060290c315e28834693515721b823d
https://doi.org/10.1111/1467-9507.00083
https://doi.org/10.1111/1467-9507.00083
Publikováno v:
Social Development. 10:74-78
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afd1dc84082b152b5f5e6f1d7eaf365b
https://doi.org/10.1111/1467-9507.00149
https://doi.org/10.1111/1467-9507.00149
Autor:
Jon Sutton, Edmund Keogh
Publikováno v:
Personality and Individual Differences. 30:137-148
Components of Machiavellian beliefs were assessed in a sample of 198 children aged 9–12 years, and related to the psychoticism (P), extraversion (E), neuroticism (N), and lie (L) scales of the Junior Eysenck Personality Questionaire (JEPQ-S) person
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::650162d6a2cc81feb915592aaaaee153
https://doi.org/10.1016/s0191-8869(00)00017-9
https://doi.org/10.1016/s0191-8869(00)00017-9
Publikováno v:
British Journal of Developmental Psychology. 18:1-11
Powell, Rosen, and Huff (1997) found a strong relationship between avoidance of responsibility and Disruptive Behaviour Disorder (DBD) symptomology in a sample of undergraduate students. Focusing on children with conduct disorder, Happe and Frith (19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba2802c422ee71048407a67369b4bc8f
https://doi.org/10.1348/026151000165517
https://doi.org/10.1348/026151000165517
Autor:
Charlotte, Grill, Jon, Sutton
Publikováno v:
Bulletin of the American College of Surgeons. 98(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::15f35cd8a80ecf4ce58301096089e920
https://pubmed.ncbi.nlm.nih.gov/24266114
https://pubmed.ncbi.nlm.nih.gov/24266114
Autor:
Kenji Namoto, François Gessier, Garry Fenton, Mandy Beswick, Finton Sirockin, Alokesh Duttaroy, Suzie Ferreira, Ulrich Hassiepen, Stefanie Flohr, Bernd Gerhartz, Jörg Trappe, Jon Sutton, Nils Ostermann, David E. Clark, Daniel K. Baeschlin, Richard Sedrani
Publikováno v:
Bioorganicmedicinal chemistry letters. 24(3)
The successful launches of dipeptidyl peptidase IV (DPP IV) inhibitors as oral anti-diabetics warrant and spur the further quest for additional chemical entities in this promising class of therapeutics. Numerous pharmaceutical companies have pursued
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9139f26205d07636435f6de6251b957e
https://pubmed.ncbi.nlm.nih.gov/24439847
https://pubmed.ncbi.nlm.nih.gov/24439847
Publikováno v:
Bulletin of the American College of Surgeons. 97(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::97a1d8fc00916b92735fddd4a1576573
https://pubmed.ncbi.nlm.nih.gov/24010253
https://pubmed.ncbi.nlm.nih.gov/24010253