Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jon Shuman"'
Autor:
Jon Shuman, Leslie P Carroll, Laura Silo-Suh, Austin Powers, Kenji Tabata, Sang-Jin Suh, Tyler X Giles
Publikováno v:
Microbiology. 164:551-562
Pseudomonas aeruginosa causes acute and chronic human infections and is the major cause of morbidity and mortality in cystic fibrosis (CF) patients. We previously determined that the sn-glycerol-3-phosphate dehydrogenase encoded by glpD plays a large
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67373cdc4e6caa800544d359bafcca5c
https://doi.org/10.1099/mic.0.000646
https://doi.org/10.1099/mic.0.000646
Publikováno v:
Journal of microbiological methods. 125
We developed an effective and rapid assay to detect both bio-energetic and envelope permeability (BEEP) alterations of Pseudomonas aeruginosa. The assay is based on quantification of extracellular ATP in bacterial cultures using luciferase as a repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54250942ba40a1eab7c6dd802778f0d7
https://pubmed.ncbi.nlm.nih.gov/27089860
https://pubmed.ncbi.nlm.nih.gov/27089860
Autor:
Philipp Kaldis, Peter F. Johnson, Songyun Zhu, Jon Shuman, Robert C. Smart, Terry D. Copeland, Thomas Sebastian
Publikováno v:
Molecular and Cellular Biology. 24:7380-7391
CCAAT/enhancer binding protein beta (C/EBPbeta) is a widely expressed transcription factor whose activity is regulated by oncogenic Ha-RasV12 signaling. C/EBPbeta is essential for the development of mouse skin tumors containing Ras mutations and can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5baa8d663e40e1c2c2f3c96df682fd0b
https://doi.org/10.1128/mcb.24.17.7380-7391.2004
https://doi.org/10.1128/mcb.24.17.7380-7391.2004
Publikováno v:
Journal of Biological Chemistry. 267:19396-19403
Four DNA-recombinant proteins, corresponding to the DNA-binding domain of CCAAT/enhancer binding protein (C/EBP), were phosphorylated in vitro by protein kinase C (PKC). High-performance liquid chromatography-peptide mapping of 32P-labeled C/EBP indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5683fb097d12fccac10b9861b85ad554
https://doi.org/10.1016/s0021-9258(18)41789-9
https://doi.org/10.1016/s0021-9258(18)41789-9
Publikováno v:
Biochemistry. 30:9030-9034
Leucine zipper proteins comprise a recently identified class of DNA binding proteins that contain a bipartite structural motif consisting of a "leucine zipper" dimerization domain and a segment rich in basic residues responsible for DNA interaction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056fac6620b63b9fd1c79ecbed0fb800
https://doi.org/10.1021/bi00101a017
https://doi.org/10.1021/bi00101a017
Autor:
William J. Roesler, Jon Shuman, Jack D. Thatcher, Alan D. Friedman, Richard W. Hanson, Dwight J. Klemm, Austin L. Gurney, Edwards A. Park, Jinsong Liu
Publikováno v:
Molecular and Cellular Biology. 10:6264-6272
Previous studies have identified a region in the promoter of the gene for phosphoenolpyruvate carboxykinase (GTP) (PEPCK) (positions -460 to +73) containing the regulatory elements which respond to cyclic AMP, glucocorticoids, and insulin and confer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13af28737e64c0f6495d40594993c415
https://doi.org/10.1128/mcb.10.12.6264
https://doi.org/10.1128/mcb.10.12.6264
Autor:
Richard C. Schwartz, Srinivasan Durairaj, Thomas Sebastian, Chauncey J. Spooner, Peter F. Johnson, Xiangrong Guo, Jon Shuman
Publikováno v:
Cytokine. 37(2)
C/EBPbeta is a member of the CCAAT/enhancer binding protein family of transcription factors and has been shown to be a critical transcriptional regulator of various proinflammatory genes, including IL-6 and MCP-1. Serine 64 in the transactivation dom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ba0cd94ff5de51e24204bed75f6c780
https://pubmed.ncbi.nlm.nih.gov/17433708
https://pubmed.ncbi.nlm.nih.gov/17433708
Autor:
Selvaggia Sciortino, Tomohiko Tamura, Vladimir P. Bermudez, Keiko Ozato, Anup Dey, Andrea Farina, Jae Hun Cheong, Jon Shuman, Jerard Hurwitz, Tetsuo Maruyama
Brd4 belongs to the BET family of nuclear proteins that carry two bromodomains implicated in the interaction with chromatin. Expression of Brd4 correlates with cell growth and is induced during early G(1) upon mitogenic stimuli. In the present study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1228ea4f819d85f9ed53e6ef1382de
https://europepmc.org/articles/PMC135621/
https://europepmc.org/articles/PMC135621/
Publikováno v:
Science (New York, N.Y.). 249(4970)
The transcription factor C/EBP uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic alpha helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb927704bc5db8e84cef6e016a9255c
https://pubmed.ncbi.nlm.nih.gov/2202050
https://pubmed.ncbi.nlm.nih.gov/2202050
Autor:
Alan Przybyla, Jon Shuman
Publikováno v:
DNA. 7:475-482
Rat tissue cultures cells respond to stress by inducing the synthesis of about 20 proteins, including two low-molecular-weight species of about 31 kD and 27 kD. We have cloned a cDNA for the 31-kD protein. This protein is induced in myoblasts and hep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::951cafbb31ec3d60ee6eb428e3f7bd8f
https://doi.org/10.1089/dna.1.1988.7.475
https://doi.org/10.1089/dna.1.1988.7.475