Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jon R. Heylings"'
Autor:
Jon R. Heylings
Publikováno v:
Qeios.
Autor:
Jon R. Heylings
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 113
Autor:
Eric Fabian, M. Aggarwal, Richard C. Peffer, Kristie Sullivan, Jon R. Heylings, C. Wiemann, Prakashchandra P V Shah, Jonathan M Akins, Hans Raabe
Publikováno v:
Regulatory Toxicology and Pharmacology. 90:197-205
Although an internationally-adopted in vitro dermal absorption test guideline is available (OECD Test Guideline 428), the replacement of the in vivo approach in North America for pesticide formulations has not occurred due to concern over the reliabi
usc The aim of this study was to investigate a range of poly(amidoamine) (PAMAM) dendrimer generations against Gram-positive and Gram-negative skin pathogens and to determine any differences in antimicrobial potency for different generations, charact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::823d988d3c154ea0305ebfdbdc77d4e7
The OECD test guideline 428 for the assessment of dermal absorption in vitro has been in force for more than a decade. Various sectors of industry utilise the method for the registration of chemical products. These include the Agrochemical and Cosmet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20f09c55f5562c8ea28753c1ef99a996
Skin penetration and localisation of chlorhexidine digluconate (CHG) within the skin have been investigated in order to better understand and optimise the delivery using a nano polymeric delivery system of this topically-applied antimicrobial drug. F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57913358c9fd8f0119049a4511957fc1
Publikováno v:
Pharmaceutical Research. 30:1896-1905
In order to increase the efficacy of a topically applied antimicrobial compound the permeation profile, localisation and mechanism of action within the skin must first be investigated. Time-of-flight secondary ion mass spectrometry (ToF-SIMS) was use
A new in vitro model based on the electrical resistance properties of the skin barrier has been established in this laboratory. The model utilises a tape stripping procedure in dermatomed pig skin that removes a specific proportion of the stratum cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::773d0936e06328bdac0e7757bf22a173
Autor:
Valérie Zuang, Chantra Eskes, Philip A. Botham, A. Worth, S. Hoffmann, J. H. Fentem, Jon R. Heylings, T. Hartung, T. Cole, Manfred Liebsch, Horst Spielmann, R. Roguet
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 369:136-140