Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jon Patteson"'
Autor:
Jon Patteson, Ellis Huff, Ahmad J. Obaidullah, James A. Sikorski, Alex Shimozono, John T. Gupton, Evan Crawford, Scott Yeudall, Nakul Telang, Wen Juekun, Cristina C. Rohena, Joe Ortolani, Andrew Harrison, Michael Kimmel, Kristin Lescalleet, Susan L. Mooberry, William Curry, Megan E. Hoerrner, Veronica Moore-Stoll, Katie Lounsbury, Glen E. Kellogg
Publikováno v:
Bioorganic & Medicinal Chemistry. 25:3206-3214
New microtubule depolymerizing agents with potent cytotoxic activities have been prepared with a 5-cyano or 5-oximino group attached to a pyrrole core. The utilization of ortho activation of a bromopyrrole ester to facilitate successful Suzuki-Miyaur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c746da3d09d873926805178613f0d2d1
https://doi.org/10.1016/j.bmc.2017.04.012
https://doi.org/10.1016/j.bmc.2017.04.012
Autor:
Jon Patteson, Eugene E. Kwan, Benjamin H. Rotstein, Lu Wang, Steven H. Liang, Neil Vasdev, Richard Y. Liu
Publikováno v:
Chemical Science. 7:4407-4417
Synthesis of non-activated electron-rich and sterically hindered 18F-arenes remains a major challenge due to limitations of existing radiofluorination methodologies. Herein, we report on our mechanistic investigations of spirocyclic iodonium(III) yli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a52a6c538242fae0529f792fadd277a7
https://doi.org/10.1039/c6sc00197a
https://doi.org/10.1039/c6sc00197a
Autor:
Nakul Telang, John Sobieski, Scott Yeudall, Kristin Lescalleet, Andrew Harrison, John T. Gupton, Jon Patteson, Will Curry
Publikováno v:
ChemInform. 46
The natural products lycogarubin (I), permethyl storniamide A (II), and lamellarin G trimethyl ether (III) are interesting biological active compounds.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc05469ab18221fcaae4f4192214e34d
https://doi.org/10.1002/chin.201520256
https://doi.org/10.1002/chin.201520256
Autor:
Scott Yeudall, Nakul Telang, John T. Gupton, Kristin Lescalleet, Will Curry, Andrew Harrison, Jon Patteson, John Sobieski
Lycogarubin C, permethyl storniamide A and lamellarin G trimethyl ether are pyrrole containing, natural products, which exhibit interesting biological properties. Such properties include anti-tumor activity on a variety of cancer cell lines including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36391efb3da1bbf60cb41c3cf0c31ae7
https://europepmc.org/articles/PMC4288030/
https://europepmc.org/articles/PMC4288030/
Autor:
Andrew Harrison, Kristin Lescalleet, Michael Kimmel, John Sobieski, Emily J. Kluball, Nakul Telang, Jon Patteson, John T. Gupton, Michael Wormald, Will Curry, Thomas Perry, Megan E. Hoerrner
A new pyrrole building block is described, which allows for the regiospecific synthesis of 2,3,5-trisubstituted pyrroles and 2,3,4,5-tetrasubstituted pyrroles. Optimization studies are presented for the preparation of the pyrrole building block along
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eefe97d3294fbd48829462a1e31c0d7
https://europepmc.org/articles/PMC4004070/
https://europepmc.org/articles/PMC4004070/