Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jon Palma"'
Publikováno v:
Biomedicine & Pharmacotherapy. 63:331-336
Heart failure is associated with abnormalities in betaAR cascade regulation, calcium cycling, expression of inflammatory mediators and apoptosis. Adenoviral mediated gene transfer of betaARKct has beneficial indirect effects on these pathologic proce
Autor:
Jon Palma, Dipin Gupta, Mahender Macha, Ezequiel J. Molina, Steven R. Houser, John P. Gaughan, Denise M. Torres
Publikováno v:
Journal of Surgical Research. 153:287-294
Background We studied a novel animal model of pressure overload hypertrophy in transition to heart failure following ascending aortic constriction. We sought to assess chronologic changes in hemodynamic parameters, echocardiographic signs of left ven
Autor:
Jon Palma, Mahender Macha, Dipin Gupta, Ezequiel J. Molina, John P. Gaughan, Steven R. Houser, Denise M. Torres
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 3:85-91
Changes in ventricular extracellular matrix (ECM) composition of pressure overload hypertrophy determine clinical outcomes. The effects of mesenchymal stem cell (MSC) transplantation upon determinants of ECM composition in pressure overload hypertrop
Autor:
Jon Palma, Mahender Macha, Ezequiel J. Molina, Steven R. Houser, Walter K. Long, Dipin Gupta, John P. Gaughan
Publikováno v:
Journal of Surgical Research. 145:257-265
We hypothesized that sarcoplasmic reticulum Ca2+ ATPase pump (SERCA-2a) gene delivery would have beneficial effects upon exercise capacity and markers of inflammation in the setting of heart failure.A pressure-overload model of experimental heart fai
Autor:
Ezequiel J. Molina, Jon Palma, Dipin Gupta, Steven R. Houser, John P. Gaughan, Mahender Macha
Publikováno v:
Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 63(10)
In a rat model of left ventricular pressure overload hypertrophy with biventricular failure, we studied the effects of intracoronary delivery of mesenchymal stem cells (MCS) upon right ventricular hemodynamic performance, profiles of local inflammati
Publikováno v:
Cardiovascular drugs and therapy. 22(5)
We hypothesized that intracoronary adenoviral-mediated delivery of betaARKct would improve heart failure associated pathophysiologic abnormalities related to exercise capacity, cardiac contractility, systemic inflammation and volume overload.After ao
Publikováno v:
Heart and vessels. 21(4)
A 65-year-old man presented to the emergency room following an episode of syncope. His vital signs and physical examination were unremarkable. A chest X-ray and an ECG were also normal. He was admitted to the hospital for further work-up. A computed
Publikováno v:
International Journal of Cardiology. 118:e92-e93
We present a case of a 53-year-old man with complaints of severe abdominal pain and nausea. Emergency department abdominal workup was non-diagnostic. Physical examination revealed signs of right- and left-heart failure. A past medical history of dysr
Autor:
Steven R. Houser, Jon Palma, Ezequiel J. Molina, John P. Gaughan, Mahender Macha, Dipin Gupta, Denise M. Torres
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 135:292-299.e1
ObjectivesIn a rat model of pressure overload hypertrophy, we studied the effects of intracoronary delivery of mesenchymal stem cells on hemodynamic performance, exercise capacity, systemic inflammation, and left ventricular reverse remodeling.Method
Publikováno v:
Cardiovascular Drugs & Therapy; Oct2008, Vol. 22 Issue 5, p373-381, 9p