Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jon P. Klein"'
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S24, Pp 1-8 (2019)
Abstract Background Emerging evidence suggests retroviruses play a role in the pathophysiology of amyotrophic lateral sclerosis (ALS). Specifically, activation of ancient viral genes embedded in the human genome is theorized to lead to motor neuron d
Externí odkaz:
https://doaj.org/article/ebd1934fc9834ddb886cb5960cdf1a9b
Autor:
Soumya M. Turaga, Mihaela E. Sardiu, Vikalp Vishwakarma, Amrita Mitra, Leonidas E. Bantis, Rashna Madan, Michael L. Merchant, Jon B. Klein, Glenson Samuel, Andrew K. Godwin
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Ewing Sarcoma (EWS) is the second most common osseous malignancy in children and young adults after osteosarcoma, while it is the fifth common osseous malignancy within adult age population. The clinical presentation of EWS is quite often non-specifi
Externí odkaz:
https://doaj.org/article/4b02e8c5b1884a21aa60e87ca60f3fb2
Predicting and Defining Steroid Resistance in Pediatric Nephrotic Syndrome Using Plasma Metabolomics
Autor:
Jessica R. Gooding, Shipra Agrawal, Susan McRitchie, Zach Acuff, Michael L. Merchant, Jon B. Klein, William E. Smoyer, Susan J. Sumner, John Mahan, Hiren Patel, Richard F. Ransom, Cynthia Pan, Denis F. Geary, Myra L. Chang, Keisha L. Gibson, Franca M. Iorember, Patrick D. Brophy, Tarak Srivastava, Larry A. Greenbaum
Publikováno v:
Kidney International Reports, Vol 5, Iss 1, Pp 81-93 (2020)
Introduction: Nephrotic syndrome (NS) is a kidney disease that affects both children and adults. Glucocorticoids have been the primary therapy for >60 years but are ineffective in approximately 20% of children and approximately 50% of adult patients.
Externí odkaz:
https://doaj.org/article/1b5280e5d877451bafee09b406b2ee8f
Autor:
Shipra Agrawal, Michael L. Merchant, Jiro Kino, Ming Li, Daniel W. Wilkey, Adam E. Gaweda, Michael E. Brier, Melinda A. Chanley, Jessica R. Gooding, Susan J. Sumner, Jon B. Klein, William E. Smoyer, John Mahan, Hiren Patel, Richard F. Ransom, Cynthia Pan, Denis F. Geary, Myra L. Chang, Keisha L. Gibson, Franca M. Iorember, Patrick D. Brophy, Tarak Srivastava, Larry A. Greenbaum
Publikováno v:
Kidney International Reports, Vol 5, Iss 1, Pp 66-80 (2020)
Introduction: Nephrotic syndrome (NS) is a characterized by massive proteinuria, edema, hypoalbuminemia, and dyslipidemia. Glucocorticoids (GCs), the primary therapy for >60 years, are ineffective in approximately 50% of adults and approximately 20%
Externí odkaz:
https://doaj.org/article/4a6071bc69c54f03bf4f8c130ca5d000
Publikováno v:
BMC Medical Education, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Compassionate health care is associated with positive patient outcomes. Educational interventions for medical students that develop compassion may also increase wellness, decrease burnout, and improve provider-patient relationship
Externí odkaz:
https://doaj.org/article/441684e90958478eafc2f5d1011d70f1
Publikováno v:
BMC Nephrology, Vol 19, Iss 1, Pp 1-9 (2018)
Abstract Background Acute kidney injury (AKI) is a common post-cardiac surgery complication and influences patient morbidity and prognosis. This study was designed to identify preoperative candidate urine biomarkers in patients undergoing cardiac sur
Externí odkaz:
https://doaj.org/article/cc2dde211fac41ef9710e8abbcca0a74
Autor:
Shunying Jin, Michael L Merchant, Jeffrey D Ritzenthaler, Kenneth R McLeish, Eleanor D Lederer, Edilson Torres-Gonzalez, Mostafa Fraig, Michelle T Barati, Alex B Lentsch, Jesse Roman, Jon B Klein, Madhavi J Rane
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0121637 (2015)
Immune-complexes play an important role in the inflammatory diseases of the lung. Neutrophil activation mediates immune-complex (IC) deposition-induced acute lung injury (ALI). Components of gamma amino butyric acid (GABA) signaling, including GABA B
Externí odkaz:
https://doaj.org/article/241d62c110c54c75a52fcfa8b728e13c
Autor:
Nichola C Garbett, Michael L Merchant, C William Helm, Alfred B Jenson, Jon B Klein, Jonathan B Chaires
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84710 (2014)
Improved methods for the accurate identification of both the presence and severity of cervical intraepithelial neoplasia (CIN) and extent of spread of invasive carcinomas of the cervix (IC) are needed. Differential scanning calorimetry (DSC) has rece
Externí odkaz:
https://doaj.org/article/09cf011b9a9d40928773b730e7dea6fe
Autor:
Raymond A. Moore, Jon P. Klein, Nathan P. Staff, Busranur Agac, Sybil C. L. Hrstka, Isabella Schneider, Bhavya Narapureddy, Soneela Ankam, Ronald F. Hrstka, Surendra Dasari
Publikováno v:
Exp Neurol
The neurotoxic effects of the chemotherapeutic agent bortezomib on dorsal root ganglia sensory neurons are well documented, yet the mechanistic underpinnings that govern these cellular processes remain incompletely understood. In this study, system-w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::747d4c5d024632b8818c5a2e835ce74c
https://pubmed.ncbi.nlm.nih.gov/33129842
https://pubmed.ncbi.nlm.nih.gov/33129842
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S24, Pp 1-8 (2019)
BMC Bioinformatics
BMC Bioinformatics
Background Emerging evidence suggests retroviruses play a role in the pathophysiology of amyotrophic lateral sclerosis (ALS). Specifically, activation of ancient viral genes embedded in the human genome is theorized to lead to motor neuron degenerati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dea78e5e5deaea57872c8347943fcf80
https://doi.org/10.1186/s12859-019-3249-8
https://doi.org/10.1186/s12859-019-3249-8