Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jon Oberdorf"'
Autor:
Irute Girkontaite, Jon Oberdorf, William A. Horton, Chelsea S. Bahney, Jeremie Larouche, Klaus von der Mark, Bruce A. Boston, Sarah M. Almubarak, Michael D. Aiona, Ryan F. Coghlan, Daniel Coleman, Susan Sienko, Gregory P. Lunstrum, Kara J. Connelly
Publikováno v:
Science Translational Medicine
Despite its importance as a key parameter of child health and development, growth velocity is difficult to determine in real time because skeletal growth is slow and clinical tools to accurately detect very small increments of growth do not exist. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5414fc2485068a98a49b667471711ace
https://doi.org/10.1530/ey.15.5.10
https://doi.org/10.1530/ey.15.5.10
Publikováno v:
Biochemical Journal. 339:453-461
Activation of certain phosphoinositidase-C-linked cell-surface receptors is known to cause an acceleration of the proteolysis of inositol 1,4,5-trisphosphate [Ins(1,4,5)P3] receptors and, thus, lead to Ins(1,4,5)P3-receptor down-regulation. In the cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb6c74df46b0a40885d48db21abc0adf
https://doi.org/10.1042/bj3390453
https://doi.org/10.1042/bj3390453
Autor:
Jon Oberdorf, Janet R. Pfeiffer, Janet M. Oliver, Richard J.H. Wojcikiewicz, Alex J. Smith, Bridget S. Wilson
Publikováno v:
Molecular Biology of the Cell. 9:1465-1478
Rat basophilic leukemia (RBL-2H3) cells predominantly express the type II receptor for inositol 1,4,5-trisphosphate (InsP3), which operates as an InsP3-gated calcium channel. In these cells, cross-linking the high-affinity immunoglobulin E receptor (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d9b80549b206acd4b0ae91ee0358eb8
https://doi.org/10.1091/mbc.9.6.1465
https://doi.org/10.1091/mbc.9.6.1465
Autor:
Kristine S. Alexander, Caryn K. Snyder, Steven C. Kazmierczak, David H. Farrell, Jon Oberdorf
Publikováno v:
Clinical Chemistry and Laboratory Medicine. 51
Although a variety of biochemical markers are used to help predict the risk of cardiovascular disease, the prognostic utility of any marker used as a risk assessment tool is dependent on the long- and short-term biological variability that the marker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e589610d4893662e4c408829cd2306
https://doi.org/10.1515/cclm-2012-0750
https://doi.org/10.1515/cclm-2012-0750
Publikováno v:
Journal of cell science. 119(Pt 2)
The 26S proteasome is the primary protease responsible for degrading misfolded membrane proteins in the endoplasmic reticulum. Here we examine the specific role of β subunit function on polypeptide cleavage and membrane release of CFTR, a prototypic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd31f3a3b4c40c0f8f9dfe6f98df037
https://pubmed.ncbi.nlm.nih.gov/16390870
https://pubmed.ncbi.nlm.nih.gov/16390870
Autor:
Jon, Oberdorf, William R, Skach
Publikováno v:
Methods in molecular medicine. 70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6e44f1b1aca467ce989abd647a58339e
https://pubmed.ncbi.nlm.nih.gov/11917531
https://pubmed.ncbi.nlm.nih.gov/11917531
Publikováno v:
Biochemistry. 40(44)
Misfolded proteins in the endoplasmic reticulum (ER) are degraded by N-terminal threonine proteases within the 26S proteasome. Each protease is formed by an activated beta subunit, beta5/X, beta1/Y, or beta2/Z, that exhibits chymotrypsin-like, peptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50add84caed6e7ec079693efb4cafd5
https://pubmed.ncbi.nlm.nih.gov/11683650
https://pubmed.ncbi.nlm.nih.gov/11683650
Publikováno v:
Journal of neurochemistry. 69(5)
Previous studies have shown that as rat cerebellar granule cell cultures differentiate in the presence of 25 mM KCl, they "up-regulate" their ability to form inositol phosphates and release Ca2+ from internal stores in response to the activation of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a87e093174cc2f681ea33a559337e468
https://pubmed.ncbi.nlm.nih.gov/9349533
https://pubmed.ncbi.nlm.nih.gov/9349533
Publikováno v:
The Journal of biological chemistry. 271(28)
Inositol 1,4,5-trisphosphate (InsP3) receptors are down-regulated in response to chronic activation of certain cell surface receptors because their degradation is accelerated. Studies on the nature of the down-regulatory process and the protease(s) r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::207f1327666bb491eace02b9174a3674
https://pubmed.ncbi.nlm.nih.gov/8663308
https://pubmed.ncbi.nlm.nih.gov/8663308
Publikováno v:
The Journal of Cell Biology
Isolated cortices from unfertilized sea urchin eggs sequester calcium in an ATP-dependent manner when incubated in a medium containing free calcium levels characteristic of the resting cell (approximately 0.1 microM). This ATP-dependent calcium uptak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab9a83f7a5169d3acdda11a2ab8c21c
https://doi.org/10.1083/jcb.102.6.2205
https://doi.org/10.1083/jcb.102.6.2205