Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Jon M. Walro"'
Autor:
Michael B. Maron, Walter I. Horne, J. Gary Meszaros, Hans G. Folkesson, Vahagn Ohanyan, Charles F. Pilati, Shyny Koshy, Daniel J. Luther, Jon M. Walro, Tianbo Li
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 297:L487-L495
The alveolar epithelium plays a critical role in resolving pulmonary edema. We thus hypothesized that its function might be upregulated in rats with heart failure, a condition that severely challenges the lung's ability to maintain fluid balance. Hea
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 289:L349-L354
Isoproterenol (Iso) infusion for 48 h in rats decreases the ability of β-adrenoceptor (β-AR) agonists to increase alveolar liquid clearance (ALC). An impairment in protein kinase A (PKA) function appears to be critical in producing the desensitized
Publikováno v:
Developmental Dynamics. 223:389-401
ER81, a member of the ETS family of transcription factors, is essential for the formation of connections between sensory and motor neurons in the spinal cord. Mice lacking Er81 genes exhibit reduced monosynaptic sensory-motoneuron connectivity in res
Publikováno v:
Experimental Neurology. 170:121-128
Deletion of a single copy of the BDNF gene has been shown to affect the nigrostriatal dopaminergic system of young adult BDNF mice. In the present report we evaluated various indices of nigrostriatal dopaminergic function between 9-month-old wild-typ
Autor:
Jon M. Walro, Jan Kucera
Publikováno v:
Trends in Neurosciences. 22:180-184
Multiple isoforms of the contractile protein myosin are present in mammalian skeletal muscles. The diversity of the heavy-chain subunits of myosin (MyHCs) in intrafusal fibers is thought to reflect a pathway of differentiation that is unique to muscl
Publikováno v:
Developmental Brain Research, 111(2), 295-300
Fusimotor neurons, group Ia afferents and muscle spindles are absent in mutant mice lacking the gene for neurotrophin-3 (NT3). To partition the effect of Ia afferent or spindle absence from that of NT3 deprivation on fusimotor neuron development, we
Publikováno v:
Muscle & Nerve. 20:1549-1560
Whether afferents exert their morphogenetic influence on spindles through release of trophic factors at intrafusal fiber junctions or via participation in proprioceptive pathways which modulate the motor activity to muscles was investigated by compar
Publikováno v:
The Anatomical Record. 249:32-43
BACKGROUND Rat intrafusal fibers consist of multiple isoforms of myosin heavy chains (MHCs) whose expression involves complex interactions among motor neurons, sensory neurons, and muscle cells during spindle development. Little is known about the ro
Publikováno v:
Neuroscience. 69:321-330
The effects of a deficiency of neurotrophin-3 on spinal motor neurons were assessed by determining the number of myelinated nerve fibers in lumbar ventral spinal roots of mice with a deletion in the neurotrophin-3 gene. Few or no small-caliber (fusim
Autor:
Jon M. Walro, Jan Kucera
Publikováno v:
Neuroscience Letters. 145:47-50
Whether muscle spindles can form in muscles innervated only by afferents was investigated by removing the lumbosacral segment of the spinal cord immediately after crushing the nerve to the medial gastrocnemius (MG) muscle in newborn rats, and adminis