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pro vyhledávání: '"Jon M. Haga"'
Autor:
Mark S. Cragg, Gordon K. Smyth, Marco J Herold, Andreas Strasser, Clare L. Scott, Lina Happo, Cassandra J. Vandenberg, Elisa S. Jansen, Jon M. Haga, Grant Dewson, Belinda Phipson, Suzanne Cory, Ewa M. Michalak
Publikováno v:
Blood. 116:5256-5267
DNA-damaging chemotherapy is the backbone of cancer treatment, although it is not clear how such treatments kill tumor cells. In nontransformed lymphoid cells, the combined loss of 2 proapoptotic p53 target genes, Puma and Noxa, induces as much resis