Zobrazeno 1 - 10
of 205
pro vyhledávání: '"Jon M. Fukuto"'
Autor:
Kayleigh Griffiths, Tomoaki Ida, Masanobu Morita, Reece J. Lamb, Jordan J. Lee, Michael P. Frenneaux, Jon M. Fukuto, Takaaki Akaike, Martin Feelisch, Melanie Madhani
Publikováno v:
Redox Biology, Vol 60, Iss , Pp 102605- (2023)
Earlier studies revealed the presence of cysteine persulfide (CysSSH) and related polysulfide species in various mammalian tissues. CysSSH has both antioxidant and oxidant properties, modulates redox-dependent signal transduction and has been shown t
Externí odkaz:
https://doaj.org/article/553db8cbeb424851b58504314357e5b8
Autor:
Christopher H. Switzer, Jon M. Fukuto
Publikováno v:
Redox Biology, Vol 57, Iss , Pp 102486- (2022)
It has become apparent that hydrogen sulfide (H2S), hydropersulfides (RSSH) and other polysulfide species are all intimately linked biochemically. Indeed, at least some of the biological activity attributed to hydrogen sulfide (H2S) may actually be d
Externí odkaz:
https://doaj.org/article/2e8e952974144880b7383db052ab21ac
Hydropersulfides (RSSH) and Nitric Oxide (NO) Signaling: Possible Effects on S-Nitrosothiols (RS-NO)
Autor:
Jon M. Fukuto, Cristina Perez-Ternero, Jessica Zarenkiewicz, Joseph Lin, Adrian J. Hobbs, John P. Toscano
Publikováno v:
Antioxidants, Vol 11, Iss 1, p 169 (2022)
S-Nitrosothiol (RS-NO) formation in proteins and peptides have been implicated as factors in the etiology of many diseases and as possible regulators of thiol protein function. They have also been proposed as possible storage forms of nitric oxide (N
Externí odkaz:
https://doaj.org/article/695e062b0d8f43d98c6753b5b7f1b460
Autor:
David E. Heppner, Milena Hristova, Tomoaki Ida, Ana Mijuskovic, Christopher M. Dustin, Virág Bogdándi, Jon M. Fukuto, Tobias P. Dick, Péter Nagy, Jianing Li, Takaaki Akaike, Albert van der Vliet
Publikováno v:
Redox Biology, Vol 14, Iss , Pp 379-385 (2018)
The reversible oxidation of protein cysteine residues (Cys-SH) is a key reaction in cellular redox signaling involving initial formation of sulfenic acids (Cys-SOH), which are commonly detected using selective dimedone-based probes. Here, we report t
Externí odkaz:
https://doaj.org/article/898f22d00edd48fb8263a51951fa70c8
Autor:
Takaaki Akaike, Tomoaki Ida, Fan-Yan Wei, Motohiro Nishida, Yoshito Kumagai, Md. Morshedul Alam, Hideshi Ihara, Tomohiro Sawa, Tetsuro Matsunaga, Shingo Kasamatsu, Akiyuki Nishimura, Masanobu Morita, Kazuhito Tomizawa, Akira Nishimura, Satoshi Watanabe, Kenji Inaba, Hiroshi Shima, Nobuhiro Tanuma, Minkyung Jung, Shigemoto Fujii, Yasuo Watanabe, Masaki Ohmuraya, Péter Nagy, Martin Feelisch, Jon M. Fukuto, Hozumi Motohashi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Cysteine hydropersulfides (CysSSH) are believed to have a cellular redox protective role. Here the authors show that these species can be produced from L-cysteine by cysteinyl-tRNA synthetases and that these enzymes are also involved in mitochondrial
Externí odkaz:
https://doaj.org/article/59355d393d744dc18b1812f57d180eae
Autor:
Hisyam Abdul Hamid, Akira Tanaka, Tomoaki Ida, Akira Nishimura, Tetsuro Matsunaga, Shigemoto Fujii, Masanobu Morita, Tomohiro Sawa, Jon M. Fukuto, Péter Nagy, Ryouhei Tsutsumi, Hozumi Motohashi, Hideshi Ihara, Takaaki Akaike
Publikováno v:
Redox Biology, Vol 21, Iss , Pp - (2019)
The physiological importance of reactive sulfur species (RSS) such as cysteine hydropersulfide (CysSSH) has been increasingly recognized in recent years. We have established a reactive sulfur metabolomics analysis by using RSS metabolic profiling, wh
Externí odkaz:
https://doaj.org/article/1b2dc593936b4f80bbebc2b8ff87d3c1
Autor:
Jon M. Fukuto
Publikováno v:
Hydrogen Sulfide. :1-26
Autor:
Jon M, Fukuto
Publikováno v:
Nature chemical biology. 19(1)
Autor:
Jon M. Fukuto
Publikováno v:
Archives of Biochemistry and Biophysics. :109659
Autor:
Jessica Zarenkiewicz, Christina Perez-Ternero, Volga Kojasoy, Christopher McGinity, Vinayak S. Khodade, Joseph Lin, Dean J. Tantillo, John P. Toscano, Adrian J. Hobbs, Jon M. Fukuto
Publikováno v:
Free radical biologymedicine. 188
S-Nitrosothiol (RS-NO) generation/levels have been implicated as being important to numerous physiological and pathophysiological processes. As such, the mechanism(s) of their generation and degradation are important factors in determining their biol