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pro vyhledávání: '"Jon L Lacanlale"'
Publikováno v:
Frontiers in Nephrology, Vol 3 (2023)
CAKUT is the leading cause of end-stage kidney disease in children and comprises a broad spectrum of phenotypic abnormalities in kidney and ureter development. Molecular mechanisms underlying the pathogenesis of CAKUT have been elucidated in genetic
Externí odkaz:
https://doaj.org/article/f463b679ac97462e9c7f3b3958cf2cf9
Publikováno v:
Pediatric Nephrology. 36:1663-1672
Aberrant transforming growth factor beta (TGFβ) signaling during embryogenesis is implicated in severe congenital abnormalities, including kidney malformations. However, the molecular mechanisms that underlie congenital kidney malformations related