Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jon K. Shepherd"'
Publikováno v:
Psychopharmacology. 126:206-218
There is increasing interest in the potential functional role of the octapeptide angiotensin II (AII) in psychiatric and cognitive disorders. The novel angiotensin II (AII) receptor antagonists, losartan and PD123177, selective for the AT1 and AT2 re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de15bb274b62455bf8a2ebd2d1a3d453
https://doi.org/10.1007/bf02246450
https://doi.org/10.1007/bf02246450
Publikováno v:
Journal of psychopharmacology (Oxford, England). 5(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e75a7704df0b7880555c12cf3a74e5
https://pubmed.ncbi.nlm.nih.gov/22282834
https://pubmed.ncbi.nlm.nih.gov/22282834
Publikováno v:
Psychopharmacology. 116:56-64
The elevated "zero-maze" is a modification of the elevated plus-maze model of anxiety in rats which incorporates both traditional and novel ethological measures in the analysis of drug effects. The novel design comprises an elevated annular platform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::367f1b25d65c1805bc1daf82eb127752
https://doi.org/10.1007/bf02244871
https://doi.org/10.1007/bf02244871
Publikováno v:
Psychopharmacology. 112:55-65
Several behaviors associated with the serotonin syndrome have been reported in rats following administration of the 5-HT1A receptor agonist 8-OH-DPAT. The present investigation approached this phenomenon from an ethopharmacological perspective, and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c63743d1dea15b3b857448f676578f76
https://doi.org/10.1007/bf02247363
https://doi.org/10.1007/bf02247363
Publikováno v:
Journal of Psychopharmacology. 7:72-81
The 5-HT3 receptor antagonist ondansetron has provided a somewhat equivocal profile in a number of animal models of anxiety. The present study assessed the effects of this compound in two ethological test batteries. The Fear/Defense Test Battery (F/D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a341da83c00bd16afe63844cc848410c
https://doi.org/10.1177/026988119300700111
https://doi.org/10.1177/026988119300700111
Autor:
Robert J. Blanchard, R. John Rodgers, Abraham J. Weatherspoon, Scott M. Weiss, Jon K. Shepherd, D. Caroline Blanchard
Publikováno v:
Pharmacology Biochemistry and Behavior. 40:819-828
In a Fear/Defense Test Battery, measuring defensive reactions to a present, approaching and contacting predator, the highest dose of morphine tested (7.5 mg/kg) reliably reduced vocalization to dorsal contact, to vibrissae stimulation, and to an anes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64ae3fa2c8ab95887c0fda86970a595a
https://doi.org/10.1016/0091-3057(91)90092-g
https://doi.org/10.1016/0091-3057(91)90092-g
Autor:
R. John Rodgers, Jon K. Shepherd
Publikováno v:
European Journal of Pharmacology. 182:581-585
The effects of MDL 72832, a potent and stereoselective ligand for 5-HT1A sites, on basal nociception and non-opioid defeat analgesia in male mice were examined. Neither (+)- nor (−)-MDL 72832 significantly altered basal tail-flick latencies. In con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e8082d27c2b7e250fc8d227a9b8568
https://doi.org/10.1016/0014-2999(90)90060-j
https://doi.org/10.1016/0014-2999(90)90060-j
Autor:
R.J. Rodgers, Jon K. Shepherd
Publikováno v:
Psychopharmacology. 101:408-413
The behavioural specificity of the hyperphagic effects of 8-OH-DPAT is a controversial issue. The present study addressed this question through the introduction of behavioural competition. Feeding behaviour in male mice was assessed under both basal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab77e9462d50cc2333575a5a2893f9a9
https://doi.org/10.1007/bf02244062
https://doi.org/10.1007/bf02244062
Publikováno v:
Psychopharmacology. 133(1)
The behavioural element, stretched attend posture (SAP), is an important component of the "risk-assessment" repertoire of defensive behaviour in rodents. The present experimental paradigm was devised as a novel and simple method of eliciting high lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8285ca4c2985d32aafee64f47a76a1de
https://pubmed.ncbi.nlm.nih.gov/9335077
https://pubmed.ncbi.nlm.nih.gov/9335077
Autor:
Jon K. Shepherd, R.J. Rodgers
Publikováno v:
Psychopharmacology. 113(2)
A single prior undrugged exposure to the elevated plus-maze has been reported to reduce open arm activity on retest and to attenuate/abolish the anxiolytic response to benzodiazepines at retest intervals ranging from 48 h to 14 days. The present stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81b8e347696e159a277795ea9857a92c
https://pubmed.ncbi.nlm.nih.gov/7855188
https://pubmed.ncbi.nlm.nih.gov/7855188