Výsledky vyhledávání - "Jon K. Jacobsen"

Synthesis and quality assurance of [11C]alpha-aminoisobutyric acid (AIB), a potential radiotracer for imaging and amino acid transport studies in normal and malignant tissues

Autor: Pat Zanzonico, Boby M. Sundoro-Wu, Rodney E. Bigler, Jon K. Jacobsen, J. Robert Dahl, Bernard Schmall, Richard K. Lee, Peter S. Conti

Publikováno v: International Journal of Nuclear Medicine and Biology. 11:209-214

Carbon-I1 labeled alpha-aminoisobutyric acid (AIB), a synthetic amino acid, was prepared by the modified Bucherer-Strecker amino acid synthesis from acetone, ammonium carbonate and [ 11 C]KCN in the presence of carrier KCN. This method results in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ca36a0e385c61ae2535d88fca0e4f2
https://doi.org/10.1016/0047-0740(84)90001-9

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Selective alkylation of pyrimidyldianions: synthesis and purification of 11C labeled thymidine for tumor visualization using positron emission tomography

Autor: Jon K. Jacobsen, J. Robert Dahl, Peter S. Conti, Boby M. Sundoro-Wu, Pat Drumm, Bernard Schmall

Publikováno v: The International journal of applied radiation and isotopes. 35(8)

Reaction of 5-bromo-2'-deoxyuridine and dihydropyran in THF gave a tetrahydropyranyl ether derivative which, after treatment with n-butyllithium, was selectively alkylated in situ by [11C]methyl iodide to give [methyl-11C]thymidine and unlabeled 2'-d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11898d7836c07b6736fee444abbed48d
https://pubmed.ncbi.nlm.nih.gov/6332784

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