Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Jon K Laerdahl"'
Autor:
Åsa Schawlann Ølnes, Marianne Teigen, Jon K Laerdahl, Trond P Leren, Thea Bismo Strøm, Katrine Bjune
Publikováno v:
PLoS ONE, Vol 18, Iss 12, p e0294764 (2023)
BackgroundCholesteryl ester transfer protein (CETP) transfers cholesteryl esters in plasma from high density lipoprotein (HDL) to very low density lipoprotein and low density lipoprotein. Loss-of-function variants in the CETP gene cause elevated leve
Externí odkaz:
https://doaj.org/article/9d82e1fe83e34acc86f34783744bc040
Autor:
Natalia Berges, Meh Sameen Nawaz, Tuva Børresdatter Dahl, Lars Hagen, Magnar Bjørås, Jon K Laerdahl, Ingrun Alseth
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225081 (2019)
Endonuclease V (ENDOV) is a ribonuclease with affinity for inosine which is the deamination product of adenosine. The genomes of most organisms, including human, encode ENDOV homologs, yet knowledge about in vivo functions and gene regulation is spar
Externí odkaz:
https://doaj.org/article/8d64d470004b4056b649ebbd5430c0d2
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60935 (2013)
3',5'-cyclic adenosine monophosphate (cAMP) dependent protein kinase or protein kinase A (PKA) has served as a prototype for the large family of protein kinases that are crucially important for signal transduction in eukaryotic cells. The PKA catalyt
Externí odkaz:
https://doaj.org/article/93ae8b053e6f4790a66e27c91ff52310
Autor:
Cathrine Fladeby, Erik Sebastian Vik, Jon K Laerdahl, Christine Gran Neurauter, Julie E Heggelund, Eirik Thorgaard, Pernille Strøm-Andersen, Magnar Bjørås, Bjørn Dalhus, Ingrun Alseth
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e47466 (2012)
Loss of amino groups from adenines in DNA results in the formation of hypoxanthine (Hx) bases with miscoding properties. The primary enzyme in Escherichia coli for DNA repair initiation at deaminated adenine is endonuclease V (endoV), encoded by the
Externí odkaz:
https://doaj.org/article/bb426f79ed904e0cb7f206bd3e15855d
Autor:
Seetha V Balasingham, Ephrem Debebe Zegeye, Håvard Homberset, Marie L Rossi, Jon K Laerdahl, Vilhelm A Bohr, Tone Tønjum
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36960 (2012)
XPB, also known as ERCC3 and RAD25, is a 3' → 5' DNA repair helicase belonging to the superfamily 2 of helicases. XPB is an essential core subunit of the eukaryotic basal transcription factor complex TFIIH. It has two well-established functions: in
Externí odkaz:
https://doaj.org/article/4854c8dabf3346b0a41cc1e7eba6d88b
Autor:
Kristoffer Søberg, Anja C V Larsen, Mandy Diskar, Paul H Backe, Magnar Bjørås, Tore Jahnsen, Jon K Laerdahl, Torbjørn Rognes, Friedrich W Herberg, Bjørn S Skålhegg
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34838 (2012)
The genes PRKACA and PRKACB encode the principal catalytic (C) subunits of protein kinase A (PKA) Cα and Cβ, respectively. Cα is expressed in all eukaryotic tissues examined and studies of Cα knockout mice demonstrate a crucial role for Cα in no
Externí odkaz:
https://doaj.org/article/fc3a73b0237548fa9be1beb718b66b04
Autor:
Hanne Korvald, Anne Margrethe Mølstad Moe, F Henning Cederkvist, Bernd Thiede, Jon K Laerdahl, Magnar Bjørås, Ingrun Alseth
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25188 (2011)
2-Oxoglutarate (2OG) dependent dioxygenases are ubiquitous iron containing enzymes that couple substrate oxidation to the conversion of 2OG to succinate and carbon dioxide. They participate in a wide range of biological processes including collagen b
Externí odkaz:
https://doaj.org/article/ca98e3fbd30341829268c90e61deb7b6
Autor:
Johannes R Hov, Verena Keitel, Jon K Laerdahl, Lina Spomer, Eva Ellinghaus, Abdou ElSharawy, Espen Melum, Kirsten M Boberg, Thomas Manke, Tobias Balschun, Christoph Schramm, Annika Bergquist, Tobias Weismüller, Daniel Gotthardt, Christian Rust, Liesbet Henckaerts, Clive M Onnie, Rinse K Weersma, Martina Sterneck, Andreas Teufel, Heiko Runz, Adolf Stiehl, Cyriel Y Ponsioen, Cisca Wijmenga, Morten H Vatn, IBSEN Study Group, Pieter C F Stokkers, Severine Vermeire, Christopher G Mathew, Benedicte A Lie, Ulrich Beuers, Michael P Manns, Stefan Schreiber, Erik Schrumpf, Dieter Häussinger, Andre Franke, Tom H Karlsen
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12403 (2010)
TGR5, the G protein-coupled bile acid receptor 1 (GPBAR1), has been linked to inflammatory pathways as well as bile homeostasis, and could therefore be involved in primary sclerosing cholangitis (PSC) a chronic inflammatory bile duct disease. We aime
Externí odkaz:
https://doaj.org/article/c775ed01a0f746309d30d3ac848ea89e
Autor:
Arne Klungland, Richard William Doughty, Jon K. Laerdahl, Michael S. Neuberger, Gaute J. Nesse, Guro F. Lien, Cesilie G. Castellanos, Christina Rada, Leonardo A. Meza-Zepeda, Trine J. Meza, Liv Kleppa, Elisabeth Larsen
Flap endonuclease 1 (FEN1) processes Okazaki fragments in lagging strand DNA synthesis, and FEN1 is involved in several DNA repair pathways. The interaction of FEN1 with the proliferating cell nuclear antigen (PCNA) processivity factor is central to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a76120b96c64ed916395715a5e1e33a
https://doi.org/10.1158/0008-5472.c.6496521.v1
https://doi.org/10.1158/0008-5472.c.6496521.v1
Autor:
Arne Klungland, Richard William Doughty, Jon K. Laerdahl, Michael S. Neuberger, Gaute J. Nesse, Guro F. Lien, Cesilie G. Castellanos, Christina Rada, Leonardo A. Meza-Zepeda, Trine J. Meza, Liv Kleppa, Elisabeth Larsen
Supplementary Materials, Figures 1-5, Tables 1-4 from Early-Onset Lymphoma and Extensive Embryonic Apoptosis in Two Domain-Specific Fen1 Mice Mutants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d4aee0ecd0f3b1c49ac1de6e19c61eb
https://doi.org/10.1158/0008-5472.22370754.v1
https://doi.org/10.1158/0008-5472.22370754.v1