Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jon Gil"'
Autor:
Chiara Bruzzone, Maider Bizkarguenaga, Rubén Gil-Redondo, Tammo Diercks, Eunate Arana, Aitor García de Vicuña, Marisa Seco, Alexandre Bosch, Asís Palazón, Itxaso San Juan, Ana Laín, Jon Gil-Martínez, Ganeko Bernardo-Seisdedos, David Fernández-Ramos, Fernando Lopitz-Otsoa, Nieves Embade, Shelly Lu, José M. Mato, Oscar Millet
Publikováno v:
iScience, Vol 23, Iss 10, Pp 101645- (2020)
Summary: COVID-19 is a systemic infection that exerts significant impact on the metabolism. Yet, there is little information on how SARS-CoV-2 affects metabolism. Using NMR spectroscopy, we measured the metabolomic and lipidomic serum profile from 26
Externí odkaz:
https://doaj.org/article/6c94517cdfc74dbc8bca49abed3a345f
Autor:
Jon Gil-Ranedo, Eleanor Gonzaga, Karolina J. Jaworek, Christian Berger, Torsten Bossing, Claudia S. Barros
Publikováno v:
Cell Reports, Vol 27, Iss 10, Pp 2921-2933.e5 (2019)
Summary: Adult stem cells reactivate from quiescence to maintain tissue homeostasis and in response to injury. How the underlying regulatory signals are integrated is largely unknown. Drosophila neural stem cells (NSCs) also leave quiescence to gener
Externí odkaz:
https://doaj.org/article/09ce47b321fa476997223988634243e7
Autor:
Jon Gil-Ranedo, Eva Hernando, Laura Riolobos, Carlos Domínguez, Michael Kann, José M Almendral
Publikováno v:
PLoS Pathogens, Vol 11, Iss 6, p e1004920 (2015)
It is unknown whether the mammalian cell cycle could impact the assembly of viruses maturing in the nucleus. We addressed this question using MVM, a reference member of the icosahedral ssDNA nuclear parvoviruses, which requires cell proliferation to
Externí odkaz:
https://doaj.org/article/db36b398861445c59fe61c4f0652563c
Autor:
Jon Gil-Ranedo, Marina Mendiburu-Eliçabe, Mercedes García-Villanueva, Diego Medina, Marta del Álamo, Marta Izquierdo
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28753 (2011)
Glioblastomas (GBM) may contain a variable proportion of active cancer stem cells (CSCs) capable of self-renewal, of aggregating into CD133(+) neurospheres, and to develop intracranial tumors that phenocopy the original ones. We hypothesized that nuc
Externí odkaz:
https://doaj.org/article/31be14543c164933b6db7042b1a35167
Autor:
Katherine P. Liao, Pamela Rist, Jon Giles, Leah Santacroce, Margery A. Connelly, Robert J. Glynn, Paul Ridker, Ahmed Tawakol, Joan Bathon, Daniel H. Solomon
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-9 (2024)
Abstract Background Treatments for rheumatoid arthritis (RA) are associated with complex changes in lipids and lipoproteins that may impact cardiovascular (CV) risk. The objective of this study was to examine lipid and lipoprotein changes associated
Externí odkaz:
https://doaj.org/article/1c5c699bc81445dabdab7e0cb72982ed
Publikováno v:
PROTEOMICS. 22:2200222
Rare diseases are most often caused by inherited genetic disorders that, after translation, will result in a protein with altered function. Decreased protein stability is the most frequent mechanism associated with a congenital pathogenic missense mu
Autor:
Jon Gil-Martínez, Maider Bizkarguenaga, David Fernández-Ramos, Oscar Millet, Alexandre Bosch, Eunate Arana, Tammo Diercks, Itxaso San Juan, José M. Mato, Rubén Gil-Redondo, Ganeko Bernardo-Seisdedos, Aitor García de Vicuña, Ana Laín, Chiara Bruzzone, Fernando Lopitz-Otsoa, Nieves Embade, Shelly C. Lu, Marisa Seco, Asis Palazon
Publikováno v:
iScience, Vol 23, Iss 10, Pp 101645-(2020)
iScience
iScience, vol 23, iss 10
iScience
iScience, vol 23, iss 10
COVID-19 is a systemic infection that exerts significant impact on the metabolism. Yet, there is little information on how SARS-CoV-2 affects metabolism. Using NMR spectroscopy, we measured the metabolomic and lipidomic serum profile from 263 (traini
Autor:
Ganeko Bernardo-Seisdedos, Aitor García de Vicuña, Tammo Diercks, Nieves Embade, Itxaso San Juan, Pedro Urquiza, Eunate Arana, Maider Bizkarguenaga, Oscar Millet, Ana Laín, Chiara Bruzzone, Jon Gil-Martínez, Marisa Seco, José M. Mato, Rubén Gil-Redondo
Publikováno v:
British Journal of Haematology
COVID‐19 is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). COVID‐19 is not only a lung disease but rather a systemic syndrome where blood alterations may play a key role (1). Severe cases show a
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Cancer therapy urges targeting of malignant subsets within self-renewing heterogeneous stem cell populations. We dissect the genetic and functional heterogeneity of human glioblastoma stem cells (GSCs) within patients by their innate responses to non
Autor:
José M. Mato, Ganeko Bernardo-Seisdedos, Oscar Millet, Luca Unione, Jon Gil-Martínez, Arantza Sanz-Parra, David Fernández-Ramos, Iratxe Macías, Ana Laín, Fernando Lopitz-Otsoa
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences, Vol 22, Iss 1789, p 1789 (2021)
Volume 22
Issue 4
International Journal of Molecular Sciences, Vol 22, Iss 1789, p 1789 (2021)
Fumarylacetoacetate hydrolase (FAH) is the fifth enzyme in the tyrosine catabolism pathway. A deficiency in human FAH leads to hereditary tyrosinemia type I (HT1), an autosomal recessive disorder that results in the accumulation of toxic metabolites