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Akademický článek

A novel technique for heart-thymus en bloc transplantation in nonhuman primates.

Autor: Nawalaniec, James T.^1,2 (AUTHOR), Landino, Samantha M.^1,2 (AUTHOR), O, Jane M.² (AUTHOR), Miller, Cynthia L.^1,2 (AUTHOR), Dehnadi, Abbas² (AUTHOR), Hanekamp, Isabel² (AUTHOR), Muoio, Jayne Marie² (AUTHOR), Winter, Casey² (AUTHOR), Hays, Nicole^2,3 (AUTHOR), Allan, James S.^2,4 (AUTHOR), Madsen, Joren C.^2,5 (AUTHOR) jcmadsen@mgh.harvard.edu

Publikováno v: Scientific Reports. 12/30/2024, Vol. 14 Issue 1, p1-12. 12p.

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Clonidine Reduces Diarrhea and Sodium Loss in Patients With Proximal Jejunostomy: A Controlled Study

Autor: Karen Zaremba, Sharon Polensky, Alan L. Buchman, Anita Wallin, Chul Ahn, Jon Fryer

Publikováno v: Journal of Parenteral and Enteral Nutrition. 30:487-491

Patients with short bowel syndrome have significant fluid losses. This represents a significant management problem, especially in patients with minimal residual intestine. We determined whether clonidine, an alpha2-adrenergic agonist, is effective in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64f15c0b013eca41b6a4d489d5cfdfc
https://doi.org/10.1177/0148607106030006487

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Quadruple Immunosuppression in a Pig Model of Small Bowel Transplantation

Autor: Sung Kim, Raouf E. Nakhleh, Angelika C. Gruessner, Jon Fryer, John S. Najarian, C. Moon, Christoph Troppmann, Carlos G. Fasola, David S. Beebe, Rainer W.G. Gruessner

Publikováno v: Journal of Surgical Research. 61:260-266

Rejection remains a major obstacle to successful small bowel transplantation in humans, irrespective of the immunosuppressants. Previous large animal studies have not used quadruple immunosuppression (with high-dose intravenous cyclosporine A [CSA])

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffece0a331c9350e35a23d2bb1ee0f7c
https://doi.org/10.1006/jsre.1996.0114

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Macronutrient absorption characteristics in humans with short bowel syndrome and jejunocolonic anastomosis: starch is the most important carbohydrate substrate, although pectin supplementation may modestly enhance short chain fatty acid production and fluid absorption

Autor: Antwan Atia, Fernand Girard-Pipau, Xavier Hébuterne, Chul Ahn, Antonella Guardiola, Fengtian Xue, William G. Spies, Meena Rammohan, Mariquita Sumague, Klaus Englyst, Alan L. Buchman, Jon Fryer

Publikováno v: JPEN. Journal of parenteral and enteral nutrition. 35(2)

Diet may play an important role in the management of patients with short bowel syndrome who have colon in continuity. However, macronutrient absorption has not been well characterized, and the most appropriate dietary constituents have not been well

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60d37c2cf03e1564b2e8ef254aab316f
https://pubmed.ncbi.nlm.nih.gov/21378253

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Comparison of the effect of rapamycin and FK506 on release of prostacyclin and endothelin in vitro

Autor: James A. Thliveris, Jon Fryer, Randall W. Yatscoff

Publikováno v: Clinical Biochemistry. 26:409-414

Alterations in mesangial and endothelial cell production of vasoactive substances may be a contributing factor to the decreased renal blood flow and glomerular thrombosis associated with FK506 nephrotoxicity. In preliminary studies Rapamycin (RAPA) a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd28ea20779315e586ed6efc4fa4b2db
https://doi.org/10.1016/0009-9120(93)90118-p

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THE RELATIONSHIP OF BLOOD CONCENTRATIONS OF RAPAMYCIN AND CYCLOSPORINE TO SUPPRESSION OF ALLOGRAFT REJECTION IN A RABBIT HETEROTOPIC HEART TRANSPLANT MODEL1

Autor: Randall W. Yatscoff, Jon Fryer, Edward Pascoe, James A. Thliveris

Publikováno v: Transplantation. 55:340-345

Heterotopic heart transplants were performed on 50 New Zealand white rabbits. Groups of 5 rabbits were randomly assigned to receive, through an intravenous route, rapamycin (RAPA) or cyclosporine at the following doses: RAPA (0.05, 0.1, 0.5, and 1.0

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ff7559a280ec15967c029a79eac7b5d
https://doi.org/10.1097/00007890-199302000-00021

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