Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jon F. Denissen"'
Autor:
H. L. Sham, Kent D. Stewart, Kennan C. Marsh, Chang H. Park, Thomas Herrin, Xiang-Peng Kong, C. Zhao, Dale J. Kempf, David A. Betebenner, J. J. Plattner, Akhter Molla, T. Robins, D. W. Norbeck, Shuqun Lin, Ayda Saldivar, N. Lyons, Darold L. Madigan, W. Jun. Rosenbrook, Edith McDonald, Jon F. Denissen, Norman Wideburg, Suthida Vasavanonda
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a6f00d92d07b9ab95319d0efe6ff86a
https://doi.org/10.1002/chin.199619188
https://doi.org/10.1002/chin.199619188
Autor:
Jon F. Denissen
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 28:1421-1426
Tin mesoporphyrin IX dichloride (Sn-MPCl2) is a heme oxygenase inhibitor of current clinical interest for the treatment of neonatal hyperbilirubinemia. The synthesis of [119mSn]-MPCl2 for drug metabolism and disposition studies is reported. [119mSn]-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a9d1c7bd021ab819f04e17474e0eb6f
https://doi.org/10.1002/jlcr.2580281210
https://doi.org/10.1002/jlcr.2580281210
Autor:
John M. Leonard, Niu P, G R Granneman, Jon F. Denissen, Akhteruzzaman Molla, G Witt, J Smith, Ann Hsu, N. Lyons, J. Girault, J P Decourt, J B Fourtillan, J Valdes, Keith Erdman, Charles Locke
Publikováno v:
Antimicrobial agents and chemotherapy. 41(5)
The multiple-dose pharmacokinetics of ritonavir were investigated in four groups of human immunodeficiency virus-positive male subjects (with 16 subjects per group) under nonfasting conditions; a 3:1 ritonavir:placebo ratio was used. Ritonavir was gi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f1b9807c2e7b355ad178c742e576472
https://pubmed.ncbi.nlm.nih.gov/9145841
https://pubmed.ncbi.nlm.nih.gov/9145841
Autor:
D W Norbeck, Eugene Sun, John M. Leonard, Dale J. Kempf, Jon F. Denissen, A D Rodrigues, Ann Hsu, Gondi N. Kumar, M J Kukulka, Jacob J. Plattner, Kennan C. Marsh, Edith McDonald, D Pizzuti, P A Baroldi, G R Granneman
Coadministration with the human immunodeficiency virus (HIV) protease inhibitor ritonavir was investigated as a method for enhancing the levels of other peptidomimetic HIV protease inhibitors in plasma. In rat and human liver microsomes, ritonavir po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c984778099e6f40f289d8c2b25bf28ea
https://europepmc.org/articles/PMC163767/
https://europepmc.org/articles/PMC163767/
Autor:
Terrel Robins, Norman E. Wideburg, William Rosenbrook, Ayda Saldivar, Suthida Vasavanonda, Hing L. Sham, Kennan C. Marsh, Kent D. Stewart, Chen Zhao, Jacob J. Plattner, Thomas Herrin, Jon F. Denissen, Nicholas Lyons, Dale J. Kempf, Xiang-P. Kong, David A. Betebenner, Darold L. Madigan, Akhter Molla, Shuqun Lin, Edith McDonald, Chang H. Park, Daniel W. Norbeck
Publikováno v:
Journal of medicinal chemistry. 39(2)
The design, synthesis, and molecular modeling studies of a novel series of azacyclic ureas, which are inhibitors of human immunodeficiency virus type 1 (HIV-1) protease that incorporate different ligands for the S1', S2, and S2' substrate-binding sit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc3fd728ccb00809b562d4b4d1353c12
https://pubmed.ncbi.nlm.nih.gov/8558507
https://pubmed.ncbi.nlm.nih.gov/8558507
Autor:
Jon F. Denissen
Publikováno v:
Journal of Chromatography A. 462:454-457
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca7c9d00127f835f0c60a68f048bfdcd
https://doi.org/10.1016/s0021-9673(00)91377-3
https://doi.org/10.1016/s0021-9673(00)91377-3
Autor:
Jon F. Denissen, Hugh N. Nellans, Robert G. Maki, Joseph F. Dellaria, Francis A. J. Kerdesky, Daniel J. Hoffman
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 27:1437-1450
A synthetic method has been developed for the iterative preparation of unlabelled and 3H-polyethylene glycol (PEG) oligomers. The strategy involved alkylating the sodium anion of mono-tritylated ethylene glycol oligomers (Ph3C[OCH2CH2]nOH, n=1−28)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01d8312db8f59214124d44aea162ae85
https://doi.org/10.1002/jlcr.2580271211
https://doi.org/10.1002/jlcr.2580271211
Publikováno v:
The Journal of Organic Chemistry. 53:2186-2192
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5e94eed1534f884f9334825ba38d7db
https://doi.org/10.1021/jo00245a012
https://doi.org/10.1021/jo00245a012
Autor:
Marianne K. Johnson, Sudthida Vasavanonda, Hing L. Sham, Dale J. Kempf, Gondi N. Kumar, Daniel W. Norbeck, John M. Leonard, Akhteruzzaman Molla, Jacob J. Plattner, Brian Grabowski, William E. Kohlbrenner, Jon F. Denissen
Publikováno v:
Virology. (2):255-262
The potency of therapeutic regimens containing human immunodeficiency virus (HIV) protease inhibitors is related to the ability to maintain concentrations of drug in the plasma of patients that are sufficient for blocking viral replication. The estim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49845f7170c92dfffe8bb5a1c7c9bd09
Publikováno v:
Journal of the American Chemical Society. 109:4399-4401
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75b7e05d519957a79cd9cb2b1ab7905e
https://doi.org/10.1021/ja00248a048
https://doi.org/10.1021/ja00248a048