OMEGA-3 MODIFY LONG-TERM CHANGES IN THE ENDOCANNABINOID SYSTEM, CANNABINOID-DEPENDENT SYNAPTIC PLASTICITY, MEMORY AND BEHAVIOR ELICITED IN ADULT MALE MICE AFTER BINGE DRINKING DURING ADOLESCENCE

Autor: Maitane Serrano Murgia, Leire Lekunberri, Miquel Saumell, Amaia Mimenza, Garazi Ocerin, Itziar Bonilla, Inmaculada Gerrikagoitia, Xabier Aretxabala, Jon Egaña, Almudena Ramos, Edgar Soria, Izaskun Elezgarai, Joan Sallés, Nagore Puente, Gontzal García, Irantzu Rico, Pedro Grandes

Publikováno v: IBRO Neuroscience Reports, Vol 15, Iss , Pp S340- (2023)

Externí odkaz: https://doaj.org/article/9559d8c925ca41938467e47ca2f32bfb

Up-regulation of CB1 cannabinoid receptors located at glutamatergic terminals in the medial prefrontal cortex of the obese Zucker rat

Autor: Leyre Echeazarra, Sergio Barrondo, Gontzal García del Caño, Itziar Bonilla-Del Río, Jon Egaña-Huguet, Nagore Puente, Xabier Aretxabala, Mario Montaña, Maider López de Jesús, Imanol González-Burguera, Miquel Saumell-Esnaola, María Aránzazu Goicolea, Pedro Grandes, Joan Sallés

Publikováno v: Frontiers in Neuroanatomy, Vol 16 (2022)

The present study describes a detailed neuroanatomical distribution map of the cannabinoid type 1 (CB1) receptor, along with the biochemical characterization of the expression and functional coupling to their cognate Gi/o proteins in the medial prefr

Externí odkaz: https://doaj.org/article/70efecff7f434c68b2dafd26fc181ffd

The Absence of the Transient Receptor Potential Vanilloid 1 Directly Impacts on the Expression and Localization of the Endocannabinoid System in the Mouse Hippocampus

Autor: Jon Egaña-Huguet, Itziar Bonilla-Del Río, Sonia M. Gómez-Urquijo, Amaia Mimenza, Miquel Saumell-Esnaola, Leire Borrega-Roman, Gontzal García del Caño, Joan Sallés, Nagore Puente, Inmaculada Gerrikagoitia, Izaskun Elezgarai, Pedro Grandes

Publikováno v: Frontiers in Neuroanatomy, Vol 15 (2021)

The transient receptor potential vanilloid 1 (TRPV1) is a non-selective ligand-gated cation channel involved in synaptic transmission, plasticity, and brain pathology. In the hippocampal dentate gyrus, TRPV1 localizes to dendritic spines and dendrite

Externí odkaz: https://doaj.org/article/044de77a0285457c8e1802d58a4f5680

Environmental Enrichment Rescues Endocannabinoid-Dependent Synaptic Plasticity Lost in Young Adult Male Mice after Ethanol Exposure during Adolescence

Autor: Irantzu Rico-Barrio, Sara Peñasco, Leire Lekunberri, Maitane Serrano, Jon Egaña-Huguet, Amaia Mimenza, Edgar Soria-Gomez, Almudena Ramos, Ianire Buceta, Inmaculada Gerrikagoitia, Juan Mendizabal-Zubiaga, Izaskun Elezgarai, Nagore Puente, Pedro Grandes

Publikováno v: Biomedicines, Vol 9, Iss 7, p 825 (2021)

Binge drinking (BD) is a serious health concern in adolescents as high ethanol (EtOH) consumption can have cognitive sequelae later in life. Remarkably, an enriched environment (EE) in adulthood significantly recovers memory in mice after adolescent

Externí odkaz: https://doaj.org/article/4fd7454ca1394755a0c7690b375789e3

The Endocannabinoid System in Glial Cells and Their Profitable Interactions to Treat Epilepsy: Evidence from Animal Models

Autor: Edgar Soria-Gomez, Jon Egaña Huguet, Pedro Grandes

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 13231, p 13231 (2021)
Addi. Archivo Digital para la Docencia y la Investigación
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Epilepsy is one of the most common neurological conditions. Yearly, five million people are diagnosed with epileptic-related disorders. The neuroprotective and therapeutic effect of (endo)cannabinoid compounds has been extensively investigated in sev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee97095cf257cdaeea09e68510d0f32f
https://pubmed.ncbi.nlm.nih.gov/34948035