Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jon E. Chatterton"'
Autor:
Edward F. Boumil, Nileyma Castro, Andrew T. Phillips, Jon E. Chatterton, Sean M. McCauley, Alexey D. Wolfson, Taisia Shmushkovich, Marc Ridilla, Audrey M. Bernstein
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 21, Iss , Pp 1029-1043 (2020)
Ocular scarring after surgery, trauma, or infection leads to vision loss. The transparent cornea is an excellent model system to test anti-scarring therapies. Cholesterol-conjugated fully modified asymmetric small interfering RNAs (siRNAs) (self-deli
Externí odkaz:
https://doaj.org/article/b53eddb735ff48938eba0574994f0165
Autor:
Marc Ridilla, Nileyma Castro, Edward F. Boumil, Alexey D. Wolfson, Jon E. Chatterton, Audrey M Bernstein, Sean M. McCauley, Taisia Shmushkovich, Andrew Phillips
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 21, Iss, Pp 1029-1043 (2020)
Molecular Therapy: Nucleic Acids, Vol 21, Iss, Pp 1029-1043 (2020)
Ocular scarring after surgery, trauma, or infection leads to vision loss. The transparent cornea is an excellent model system to test anti-scarring therapies. Cholesterol-conjugated fully modified asymmetric small interfering RNAs (siRNAs) (self-deli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9351be08091c6d316b7b47a944d53d87
https://doi.org/10.1016/j.omtn.2020.07.032
https://doi.org/10.1016/j.omtn.2020.07.032
Autor:
Bo Yang, Mingliang Qu, Rengang Wang, Jon E Chatterton, Xiao-Bo Liu, Bing Zhu, Sonoko Narisawa, Jose Luis Millan, Nobuki Nakanishi, Kathryn Swoboda, Stuart A Lipton, Dongxian Zhang
Publikováno v:
eLife, Vol 4 (2015)
Hitherto, membralin has been a protein of unknown function. Here, we show that membralin mutant mice manifest a severe and early-onset motor neuron disease in an autosomal recessive manner, dying by postnatal day 5–6. Selective death of lower motor
Externí odkaz:
https://doaj.org/article/6372ba534f6042f3a37c0d0883d048b4
Autor:
Ning Ke, Aaron Albers, Gisela Claassen, De-hua Yu, Jon E. Chatterton, Xiuyuan Hu, Bernd Meyhack, Flossie Wong-Staal, Qi-Xiang Li
Publikováno v:
BioTechniques, Vol 36, Iss 5, Pp 826-833 (2004)
Soft agar growth, used to measure cell anchorage-independent proliferation potential, is one of the most important and most commonly used assays to detect cell transformation. However, the traditional soft agar assay is time-consuming, labor-intensiv
Externí odkaz:
https://doaj.org/article/9fa135bf8e21487ea30e62b1edc78b17
Autor:
Qi-Xiang Li, Ning Ke, John Chionis, Josh Bliesath, Demin Zhou, Jon E. Chatterton, Qiuchen S. He, Cuiying Wang, Flossie Wong-Staal, Jing Zhang
Publikováno v:
RNA. 13:1375-1383
Two types of tetracycline-controlled inducible RNAi expression systems have been developed that generally utilize multiple tetracycline operators (TetOs) or repressor fusion proteins to overcome the siRNA leakiness. Here, we report a novel system tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7a888025c538745afdf66b97339a054
https://doi.org/10.1261/rna.520707
https://doi.org/10.1261/rna.520707
Autor:
Rengang Wang, Mingliang Qu, Bing Zhu, Sonoko Narisawa, Kathryn J. Swoboda, Stuart A. Lipton, Jon E. Chatterton, José Luis Millán, Nobuki Nakanishi, Bo Yang, Dongxian Zhang, Xiao-Bo Liu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53f659cb40139e70d581088607ea7d4d
https://doi.org/10.7554/elife.06500.020
https://doi.org/10.7554/elife.06500.020
Autor:
Kathryn J. Swoboda, Mingliang Qu, Sonoko Narisawa, Xiao-Bo Liu, Rengang Wang, José Luis Millán, Bing Zhu, Stuart A. Lipton, Bo Yang, Dongxian Zhang, Nobuki Nakanishi, Jon E. Chatterton
Publikováno v:
eLife
eLife, Vol 4 (2015)
eLife, Vol 4 (2015)
Hitherto, membralin has been a protein of unknown function. Here, we show that membralin mutant mice manifest a severe and early-onset motor neuron disease in an autosomal recessive manner, dying by postnatal day 5–6. Selective death of lower motor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e367efeefc504808e5f28022cd56f085
http://europepmc.org/articles/PMC4460860
http://europepmc.org/articles/PMC4460860
Autor:
Qi-Xiang Li, Jian-Ping Yang, Cuiying Wang, Cheryl Rogers, Jon E. Chatterton, Flossie Wong-Staal, Wufang Fan, Kristina Rhoades, Ning Ke, Guohong Liu, Joshua Bliesath
Publikováno v:
Genomics. 88(3):282-292
Combinatorial gene inactivation using an RNAi library is a powerful approach to discovering novel functional genes. However, generation of a comprehensive RNAi library remains technically challenging. In this report, we describe a simple and novel ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04196077e008442382e9ce71474bc52
Autor:
Vivian Nguy, Ning Ke, Shilong Long, Arndt Brachat, Qi-Xiang Li, Jon E. Chatterton, Flossie Wong-Staal, Guohong Liu, Dehua Yu, Wufang Fan, Adrian Bruengger, Bernd Meyhack
Publikováno v:
Experimental Cell Research. 312:865-876
HeLaHF is a non-transformed revertant of HeLa cells, likely resulting from the activation of a putative tumor suppressor(s). p53 protein was stabilized in this revertant and reactivated for certain transactivation functions. Although p53 stabilizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e91b3ced5eb93cba3f13fb49d1e02622
https://doi.org/10.1016/j.yexcr.2005.12.006
https://doi.org/10.1016/j.yexcr.2005.12.006
Autor:
Mirta Grifman, Qi-Xiang Li, Jon E. Chatterton, Guohong Liu, Flossie-Wong Staal, Benjamin Keily
Publikováno v:
Biochemical and Biophysical Research Communications. 342:1291-1296
The mineralocorticoid receptor (MR) is expressed in kidney and plays a central role in the control of sodium, homeostatic fluid, and blood pressure. It has also been implicated in other functions in cardiovascular system, central nervous system, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788bf14e4f10aa0010a1dbd1d1dd1e02
https://doi.org/10.1016/j.bbrc.2006.02.065
https://doi.org/10.1016/j.bbrc.2006.02.065