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pro vyhledávání: '"Jon D. Lenn"'
Several in vitro models have been designed as test systems for inflammatory skin conditions, commonly using cell-culture or reconstructed human epidermis approaches. However, these systems poorly recapitulate the physiology and, importantly, the meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701490086edb5b4b65ec0c82568db40f
Publikováno v:
International journal of pharmaceutics. 618
Although animal models have been extensively used to evaluate human topical therapeutics, they exhibit marked physiological differences to human skin. Our objective was to develop a human ex vivo skin culture model to explore the pathophysiology of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9097b73002d5f4f8569a324a27e54d2f
https://pubmed.ncbi.nlm.nih.gov/35276230
https://pubmed.ncbi.nlm.nih.gov/35276230
Autor:
Jessica Neil, Caitlin Vestal Tibbetts, Kellie Marie Demock, Susan H. Smith, Christine Patricia Donahue, Jon D. Lenn, Javier Cote-Sierra, P. Shannon Pendergrast, Jason R. Killough, Adrian C. Williams, Marc B. Brown, Jean-Philippe Therrien, David Rubenstein
Publikováno v:
The Journal of investigative dermatology. 138(2)
It is generally recognized that only relatively small molecular weight (typically∼ 500 Da) drugs can effectively permeate through intact stratum corneum. Here, we challenge this orthodoxy using a 62-nucleotide (molecular weight = 20,395 Da) RNA-bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::437fa4840700bc645675651ea77dc7e5
https://pubmed.ncbi.nlm.nih.gov/28942363
https://pubmed.ncbi.nlm.nih.gov/28942363
Autor:
Marc B. Brown, Sian Lim, Ryan F. Donnelly, Thakur Raghu Raj Singh, Charles Rodney Greenaway Evans, Jon D. Lenn
Publikováno v:
Novel Delivery Systems for Transdermal and Intradermal Drug Delivery ISBN: 9781118734506
Novel Delivery Systems for Transdermal and Intradermal Drug Delivery
Novel Delivery Systems for Transdermal and Intradermal Drug Delivery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::753ce201b40485c9ad9278f13a79fc67
https://doi.org/10.1002/9781118734506.ch11
https://doi.org/10.1002/9781118734506.ch11