Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jon D. Elsworth"'
Publikováno v:
Org. Biomol. Chem.. 8:751-754
New and simple protocols are described for the conversion of the enzymatically-derived and enantiomerically pure cis-1,2-dihydrocatechol 7 (X = I) and its 6-methylated derivative into either antipodal form of compounds embodying the tricyclic framewo
Publikováno v:
Organic Letters. 8:3319-3322
[Structure: see text] The total synthesis of the marine metabolite clavosolide A is reported which confirms the structure and absolute configuration of the natural product as the symmetrical diolide glycosylated by permethylated D-xylose moieties, 2.
Autor:
Christopher D. Bailey, Sophie J. Edwards, Jon D. Elsworth, Tshepo Pheko, Christine L. Willis, Adam J. Bunt, Benjamin D. Cons
Publikováno v:
Angewandte Chemie (International ed. in English). 51(16)
trans-2,8-Dioxabicyclodecanes were prepared in high yield with the creation of up to three stereocenters in a single pot by the acid-mediated reaction of γ,δ-unsaturated alcohols with aldehydes (see scheme, Bn=benzyl). This versatile reaction enabl
Autor:
Jon D. Elsworth, Christine L. Willis
Publikováno v:
ChemInform. 39
Autor:
Jon D. Elsworth, Christine L. Willis
Publikováno v:
Chemical communications (Cambridge, England). (13)
Methyl (4E,7R)-7-hydroxyoctanoate was prepared in 71% yield from ethyl (R)-3-hydroxybutanoate and on reaction with a series of aldehydes in the presence of TMSOTf gave bicyclic oxygen heterocycles in good yields and with the creation of three new ste
Autor:
Nick Bushby, Conor S. Barry, Jon D. Elsworth, Roger W. Alder, John R. Harding, Christine L. Willis, Peter T. Seden
Publikováno v:
ChemInform. 37
Autor:
Jon D. Elsworth, Conor S. Barry, Jonathan P. H. Charmant, Christine L. Willis, John R. Harding, Nick Bushby
Publikováno v:
ChemInform. 37
Autor:
Conor S. Barry, Jonathan P. H. Charmant, John R. Harding, Nick Bushby, Jon D. Elsworth, Christine L. Willis
Publikováno v:
Chemical communications (Cambridge, England). (40)
The first total synthesis of the reported structure of the sponge metabolite clavosolide A is described using a Prins cyclisation to assemble the tetrahydropyran core followed by manipulation of the side-chain, dimerisation and finally glycosidation.