Zobrazeno 1 - 10 of 163 pro vyhledávání: '"Jon D Simmons"'
1
Akademický článek
Amyloid-β and caspase-1 are indicators of sepsis and organ injury
Autor: Amanda N. Tuckey, Arcole Brandon, Yasaman Eslaamizaad, Waqar Siddiqui, Talha Nawaz, Christopher Clarke, Erica Sutherland, Veronica Williams, Domenico Spadafora, Robert A. Barrington, Diego F. Alvarez, Madhuri S. Mulekar, Jon D. Simmons, Brian W. Fouty, Jonathon P. Audia
Publikováno v: ERJ Open Research, Vol 10, Iss 1 (2024)
Background Sepsis is a life-threatening condition that results from a dysregulated host response to infection, leading to organ dysfunction. Despite the prevalence and associated socioeconomic costs, treatment of sepsis remains limited to antibiotics
Externí odkaz: https://doaj.org/article/0c72f16b14924bceb1769addcd732091
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2
Akademický článek
Survey of venous thromboembolism prophylaxis in trauma patients: current prescribing practices and concordance with clinical practice guidelines
Autor: Elliott R Haut, Allison E Berndtson, Todd W Costantini, David Spain, Matthew E Kutcher, Nathan Polite, Kaitlin M Alexander, Charles Caleb Butts, Yan-Leei Larry Lee, Jon D Simmons
Publikováno v: Trauma Surgery & Acute Care Open, Vol 8, Iss 1 (2023)
Objectives Pharmacological venous thromboembolism (VTE) prophylaxis is recommended in the vast majority of trauma patients. The purpose of this study was to characterize current dosing practices and timing of initiation of pharmacological VTE chemopr
Externí odkaz: https://doaj.org/article/75b4add5d79643b3af41e38efd2cdd99
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4
Akademický článek
ExoU Induces Lung Endothelial Cell Damage and Activates Pro-Inflammatory Caspase-1 during Pseudomonas aeruginosa Infection
Autor: Kierra S. Hardy, Amanda N. Tuckey, Phoibe Renema, Mita Patel, Abu-Bakr Al-Mehdi, Domenico Spadafora, Cody A. Schlumpf, Robert A. Barrington, Mikhail F. Alexeyev, Troy Stevens, Jean-Francois Pittet, Brant M. Wagener, Jon D. Simmons, Diego F. Alvarez, Jonathon P. Audia
Publikováno v: Toxins, Vol 14, Iss 2, p 152 (2022)
The Gram-negative, opportunistic pathogen Pseudomonas aeruginosa utilizes a type III secretion system to inject exoenzyme effectors into a target host cell. Of the four best-studied exoenzymes, ExoU causes rapid cell damage and death. ExoU is a phosp
Externí odkaz: https://doaj.org/article/c9f84dac36d44282a31de0221c698954
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6
Akademický článek
Craniofacial impalement injury: Projectile fragment to the head
Autor: Celia Y Quang, Lindy M Rosal, Scott G Blair, Jon D Simmons, W George Rusyniak, Sidney B Brevard
Publikováno v: Archives of Trauma Research, Vol 7, Iss 1, Pp 30-32 (2018)
Circular saws and angle grinders are two of the most dangerous pieces of electrical equipment on a worksite. Besides the danger that any high-powered, sharp piece of equipment possesses, these pieces use circular saw blades that can splinter into pro
Externí odkaz: https://doaj.org/article/0d93c041713f439ea84a8e713e0e8394
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7
Akademický článek
Plasma mitochondrial DNA is elevated in obese type 2 diabetes mellitus patients and correlates positively with insulin resistance.
Autor: Larysa V Yuzefovych, Viktor M Pastukh, Mykhaylo V Ruchko, Jon D Simmons, William O Richards, Lyudmila I Rachek
Publikováno v: PLoS ONE, Vol 14, Iss 10, p e0222278 (2019)
Cells damaged by mechanical or infectious injury release proinflammatory mitochondrial DNA (mtDNA) fragments into the circulation. We evaluated the relation between plasma levels of mtDNA fragments in obese type 2 diabetes mellitus (T2DM) patients an
Externí odkaz: https://doaj.org/article/e4fdbab1eb4b471b85614f0c42ea8360
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9
Overutilization of Helicopter Emergency Medical Services in Central Gulf Coast Region Results in Unnecessary Expenditure
Autor: M. Victoria P. Miles, Justin R. Beasley, Haylie E. Reed, Daniel T. Miles, Andrew Haiflich, Allison R. Beckett, Yann-Leei Lee, Stephen E. Bowden, Edward A. Panacek, Linda Ding, Sidney B. Brevard, Jon D. Simmons, C. Caleb Butts
Publikováno v: Journal of Surgical Research. 273:211-217
When appropriately used, helicopter emergency medical services (HEMSs) allow for timely delivery of severely injured patients to definitive care. Inappropriate utilization of HEMSs results in increased cost to the patient and trauma system. The purpo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825794ae1b067ec35ebb1f5468ec8fa5
https://doi.org/10.1016/j.jss.2021.12.038
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