Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Jon D Larson"'
Autor:
Mara E Robu, Jon D Larson, Aidas Nasevicius, Soraya Beiraghi, Charles Brenner, Steven A Farber, Stephen C Ekker
Publikováno v:
PLoS Genetics, Vol 3, Iss 5, p e78 (2007)
Morpholino phosphorodiamidate antisense oligonucleotides (MOs) and short interfering RNAs (siRNAs) are commonly used platforms to study gene function by sequence-specific knockdown. Both technologies, however, can elicit undesirable off-target effect
Externí odkaz:
https://doaj.org/article/7a76f464ccd845ad8bc0f250bb3941db
Autor:
Michael A Pickart, Eric W Klee, Aubrey L Nielsen, Sridhar Sivasubbu, Eric M Mendenhall, Brent R Bill, Eleanor Chen, Craig E Eckfeldt, Michelle Knowlton, Mara E Robu, Jon D Larson, Yun Deng, Lisa A Schimmenti, Lynda B M Ellis, Catherine M Verfaillie, Matthias Hammerschmidt, Steven A Farber, Stephen C Ekker
Publikováno v:
PLoS ONE, Vol 1, p e104 (2006)
Understanding the functional role(s) of the more than 20,000 proteins of the vertebrate genome is a major next step in the post-genome era. The approximately 4,000 co-translationally translocated (CTT) proteins - representing the vertebrate secretome
Externí odkaz:
https://doaj.org/article/ad4f62a2c075436ba76f59bb8bffea77
Autor:
Duygu Kuzuoglu-Ozturk, Ozlem Aksoy, Christin Schmidt, Robin Lea, Jon D. Larson, Ryan R.L. Phelps, Nicole Nasholm, Megan Holt, Adrian Contreras, Miller Huang, Shannon Wong-Michalak, Hao Shao, Robert Wechsler-Reya, Joanna J. Phillips, Jason E. Gestwicki, Davide Ruggero, William A. Weiss
Publikováno v:
Cancer Res
Deregulation of neuroblastoma-derived myc (N-myc) is a leading cause of malignant brain tumors in children. To target N-myc-driven medulloblastoma, most research has focused on identifying genomic alterations or on the analysis of the medulloblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3a2a42fff3def40fd356464b7546a97
https://doi.org/10.1158/0008-5472.can-22-0945
https://doi.org/10.1158/0008-5472.can-22-0945
Autor:
Suzanne J. Baker, David W. Ellison, Jinghui Zhang, Chunxu Qu, Lionel M.L. Chow, Xiaoyan Zhu, Jon D. Larson, Sherri L. Rankin, Guo Zhu
Pten deletion caused a massive increase in tumor vasculature in Pten;Tp53 dKO medulloblastomas compared to Tp53 cKO medulloblastomas.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132bfcb1916885b7411ce8dbb5c85abf
https://doi.org/10.1158/0008-5472.22413045
https://doi.org/10.1158/0008-5472.22413045
Autor:
William A. Weiss, Davide Ruggero, Jason E. Gestwicki, Joanna J. Phillips, Robert Wechsler-Reya, Hao Shao, Shannon Wong-Michalak, Miller Huang, Adrian Contreras, Megan Holt, Nicole Nasholm, Ryan R.L. Phelps, Jon D. Larson, Robin Lea, Christin Schmidt, Ozlem Aksoy, Duygu Kuzuoglu-Ozturk
Translation efficiency in Rapalink-1 and Rapamycin treated samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::377742b45975aa50a20cf91cead747f6
https://doi.org/10.1158/0008-5472.22432715
https://doi.org/10.1158/0008-5472.22432715
Autor:
David A. Largaespada, Aaron L. Sarver, Michael D. Taylor, Annie Huang, David J. Odde, Robert J. Wechsler-Reya, Robert B. Jenkins, Charles G. Eberhart, Stephen C. Schmechel, Anthony E. Rizzardi, Michelle M. Frees, Addison M. Demer, Amy M. Molan, Ryan D. Krebs, Quincy Rosemarie, Fausto J. Rodriguez, Xiaochong Wu, Daniel Picard, Branden S. Moriarity, Adrian M. Dubuc, Paramita Das, Barbara R. Tschida, Catherine Lee, Jun Wang, Rory L. Williams, George M. Otto, Ghaidan A. Shamsan, Eric P. Rahrmann, Sandra Wagner, Jason P. Ostergaard, Alex T. Larsson, Jon D. Larson, Pauline J. Beckmann
Medulloblastoma and central nervous system primitive neuroectodermal tumors (CNS-PNET) are aggressive, poorly differentiated brain tumors with limited effective therapies. Using Sleeping Beauty (SB) transposon mutagenesis, we identified novel genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebcfc7720d1848ea19440c3e7a8f431f
https://doi.org/10.1158/0008-5472.c.6511413.v1
https://doi.org/10.1158/0008-5472.c.6511413.v1
Autor:
William A. Weiss, Davide Ruggero, Jason E. Gestwicki, Joanna J. Phillips, Robert Wechsler-Reya, Hao Shao, Shannon Wong-Michalak, Miller Huang, Adrian Contreras, Megan Holt, Nicole Nasholm, Ryan R.L. Phelps, Jon D. Larson, Robin Lea, Christin Schmidt, Ozlem Aksoy, Duygu Kuzuoglu-Ozturk
Deregulation of neuroblastoma-derived myc (N-myc) is a leading cause of malignant brain tumors in children. To target N-myc-driven medulloblastoma, most research has focused on identifying genomic alterations or on the analysis of the medulloblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1befd784d6d0f3aafa60a803f1fc6010
https://doi.org/10.1158/0008-5472.c.6514226
https://doi.org/10.1158/0008-5472.c.6514226
Autor:
David A. Largaespada, Aaron L. Sarver, Michael D. Taylor, Annie Huang, David J. Odde, Robert J. Wechsler-Reya, Robert B. Jenkins, Charles G. Eberhart, Stephen C. Schmechel, Anthony E. Rizzardi, Michelle M. Frees, Addison M. Demer, Amy M. Molan, Ryan D. Krebs, Quincy Rosemarie, Fausto J. Rodriguez, Xiaochong Wu, Daniel Picard, Branden S. Moriarity, Adrian M. Dubuc, Paramita Das, Barbara R. Tschida, Catherine Lee, Jun Wang, Rory L. Williams, George M. Otto, Ghaidan A. Shamsan, Eric P. Rahrmann, Sandra Wagner, Jason P. Ostergaard, Alex T. Larsson, Jon D. Larson, Pauline J. Beckmann
Figure S4. Shows ARHGAP36 expression in mouse and human neural tissue. Figure S5. Shows characterization of ARHGAP36 and Megf10 in C17.2 cells Figures S6-S7 show mechanistic analysis of FOXR2 in C17.2 and HSC1L cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c88fb8090e9d0f93c8d64bec0f20df6
https://doi.org/10.1158/0008-5472.22423053
https://doi.org/10.1158/0008-5472.22423053
Autor:
David A. Largaespada, Aaron L. Sarver, Michael D. Taylor, Annie Huang, David J. Odde, Robert J. Wechsler-Reya, Robert B. Jenkins, Charles G. Eberhart, Stephen C. Schmechel, Anthony E. Rizzardi, Michelle M. Frees, Addison M. Demer, Amy M. Molan, Ryan D. Krebs, Quincy Rosemarie, Fausto J. Rodriguez, Xiaochong Wu, Daniel Picard, Branden S. Moriarity, Adrian M. Dubuc, Paramita Das, Barbara R. Tschida, Catherine Lee, Jun Wang, Rory L. Williams, George M. Otto, Ghaidan A. Shamsan, Eric P. Rahrmann, Sandra Wagner, Jason P. Ostergaard, Alex T. Larsson, Jon D. Larson, Pauline J. Beckmann
Characterization of SB-induced medulloblastomas and CNS-PNETs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bcf71417a72492031f7dbb0484851a0
https://doi.org/10.1158/0008-5472.22423056.v1
https://doi.org/10.1158/0008-5472.22423056.v1
Autor:
William A. Weiss, Davide Ruggero, Jason E. Gestwicki, Joanna J. Phillips, Robert Wechsler-Reya, Hao Shao, Shannon Wong-Michalak, Miller Huang, Adrian Contreras, Megan Holt, Nicole Nasholm, Ryan R.L. Phelps, Jon D. Larson, Robin Lea, Christin Schmidt, Ozlem Aksoy, Duygu Kuzuoglu-Ozturk
RNA abundance of Rapalink-1 and Rapamycin treated samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f8cdbc01c977e46aa93a5950f34ead3
https://doi.org/10.1158/0008-5472.22432721
https://doi.org/10.1158/0008-5472.22432721